Coproduction of KPC-18 and VIM-1 Carbapenemases by Enterobacter cloacae: Implications for Newer β-Lactam–β-Lactamase Inhibitor Combinations
2015 ◽
Vol 54
(3)
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pp. 791-794
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Keyword(s):
Enterobacter cloacaestrain G6809 with reduced susceptibility to carbapenems was identified from a patient in a long-term acute care hospital in Kentucky. G6809 belonged to sequence type (ST) 88 and carried two carbapenemase genes,blaKPC-18andblaVIM-1. Whole-genome sequencing localizedblaKPC-18to the chromosome andblaVIM-1to a 58-kb plasmid. The strain was highly resistant to ceftazidime-avibactam. Insidious coproduction of metallo-β-lactamase with KPC-type carbapenemase has implications for the use of next-generation β-lactam–β-lactamase inhibitor combinations.
2019 ◽
Vol 69
(10)
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pp. 1801-1804
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2012 ◽
Vol 185
(1)
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pp. 53-57
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Keyword(s):
2018 ◽
Vol 35
(8)
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pp. 745-754
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