c-fos proto-oncogene expression in the nervous system during mouse development

1989 ◽  
Vol 9 (5) ◽  
pp. 2269-2272
Author(s):  
J F Caubet
Keyword(s):  
Spinal Cord ◽  
Nervous System ◽  
In Situ Hybridization ◽  
Dorsal Root ◽  
Olfactory Lobe ◽  
Mouse Development ◽  
Fos Protein ◽  
Spinal Cord Dorsal ◽  
Late Stages

I show, by in situ hybridization, that c-fos is expressed in the nervous system during mouse development. This expression was found to be restricted to specific regions at late stages of development (day 16 postcoitum), particularly to the spinal cord, dorsal root ganglia, and olfactory lobe. The c-fos protein may play a role in the maturation of these structures by activating specific genes.

scholarly journals c-fos proto-oncogene expression in the nervous system during mouse development.

1989 ◽  
Vol 9 (5) ◽  
pp. 2269-2272 ◽  
Author(s):  
J F Caubet
Keyword(s):  
Spinal Cord ◽  
Nervous System ◽  
In Situ Hybridization ◽  
Dorsal Root ◽  
Olfactory Lobe ◽  
Mouse Development ◽  
Fos Protein ◽  
Spinal Cord Dorsal ◽  
Late Stages

I show, by in situ hybridization, that c-fos is expressed in the nervous system during mouse development. This expression was found to be restricted to specific regions at late stages of development (day 16 postcoitum), particularly to the spinal cord, dorsal root ganglia, and olfactory lobe. The c-fos protein may play a role in the maturation of these structures by activating specific genes.

In situ hybridization study of μ- and κ-opioid receptor mRNAs in the rat spinal cord and dorsal root ganglia

1994 ◽  
Vol 168 (1-2) ◽  
pp. 97-100 ◽  
Author(s):  
Keiko Maekawa ◽  
Masabumi Minami ◽  
Kazuki Yabuuchi ◽  
Takashi Toya ◽  
Yoshikazu Katao ◽  
...  
Keyword(s):  
Spinal Cord ◽  
In Situ Hybridization ◽  
Opioid Receptor ◽  
Dorsal Root Ganglia ◽  
Dorsal Root ◽  
Hybridization Study ◽  
Rat Spinal Cord ◽  
Receptor Mrnas

scholarly journals Apoptotic Cells, Including Macrophages, Are Prominent in Theiler's Virus-Induced Inflammatory, Demyelinating Lesions

2003 ◽  
Vol 77 (7) ◽  
pp. 4383-4388 ◽  
Author(s):  
Brian P. Schlitt ◽  
Matthew Felrice ◽  
Mary Lou Jelachich ◽  
Howard L. Lipton
Keyword(s):  
Central Nervous System ◽  
T Cells ◽  
Nervous System ◽  
In Situ Hybridization ◽  
Apoptotic Cells ◽  
Theiler's Virus ◽  
Demyelinating Lesions ◽  
Encephalomyelitis Virus ◽  
Mouse Central Nervous System

ABSTRACT Theiler's murine encephalomyelitis virus (TMEV) persists in the mouse central nervous system principally in macrophages, and infected macrophages in culture undergo apoptosis. We have detected abundant apoptotic cells in perivascular cuffs and inflammatory, demyelinating lesions of SJL mice chronically infected with TMEV. T cells comprised 74% of apoptotic cells, while 8% were macrophages, 0.6% were astrocytes, and ∼17% remained unidentified. In situ hybridization revealed viral RNA in ∼1% of apoptotic cells.

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