Primary physical mechanism of the biological effects of weak magnetic fields

Biological systems are constantly exposed to electromagnetic fields (EMFs) in the form of natural geomagnetic fields and EMFs emitted from technology. While strong magnetic fields are known to change chemical reaction rates and free radical concentrations, the debate remains about whether static weak magnetic fields (WMFs; <1 mT) also produce biological effects. Using the planarian regeneration model, we show that WMFs altered stem cell proliferation and subsequent differentiation via changes in reactive oxygen species (ROS) accumulation and downstream heat shock protein 70 (Hsp70) expression. These data reveal that on the basis of field strength, WMF exposure can increase or decrease new tissue formation in vivo, suggesting WMFs as a potential therapeutic tool to manipulate mitotic activity.

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Electric Relaxation Processes in Lipid-Bilayers after Exposure to Weak Magnetic Pulses

Zeitschrift für Naturforschung C ◽

10.1515/znc-2001-9-1025 ◽

2001 ◽

Vol 56 (9-10) ◽

pp. 831-837 ◽

Cited By ~ 1

Author(s):

Alexander Pazur

Keyword(s):

Magnetic Fields ◽

Lipid Bilayers ◽

Lipid Membranes ◽

Magnetic Particles ◽

Biological Effects ◽

Electrical Conductance ◽

Relaxation Processes ◽

Magnetic Pulse ◽

Frequency Spectra ◽

Weak Magnetic Fields

AbstractBiological effects of weak magnetic fields are widespread, but poorly understood. Besides magnetic particles, which have been shown to be involved in only few cases, membranes are discussed as the site of perception. However, the mechanism is unknown. We have subjected pure lipid membranes to weak magnetic pulses, and found, that their electric properties are modified.Black lipid membranes were prepared from purified asolectin on a teflon septum separating electrically the two chambers of a teflon cuvette, using the technique of Mueller et al. (1962). Single magnetic pulses were applied for 10 μs, whose intensity could be varied from 0 to 100 G (0 to 10 mT) at the membrane. Directly after the pulse decay, the conductance of the bilayers was scanned with 10 periods of a 1 kHz triangle alternating voltage (eg. a measurement time window of 10 ms). Frequency spectra of the bilayer current rose by a frequency dependent factor ≤ 2 in a broad region around 80 kHz, when the amplitude of the preceding magnetic pulse was increased from 0 to 100 G. The data show, that weak magnetic fields can significantly change the electrical conductance of lipid films. The relaxation of electrons in a two-dimensional quantum state (“quantum hollow”) will be discussed as a possible origin of these effects.

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Analysis of biological effects and limits of exposure to weak magnetic fields

2010 Fifth International Conference on Information and Automation for Sustainability ◽

10.1109/iciafs.2010.5715697 ◽

2010 ◽

Cited By ~ 1

Author(s):

D A Chathurika ◽

M F Peter ◽

N H Malka

Keyword(s):

Magnetic Fields ◽

Biological Effects ◽

Weak Magnetic Fields

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Mechanism of Action of Extremely Low Frequency or Static Magnetic Fields on Cells: Role of Oxidative Activation of TRPM2

10.20944/preprints201901.0168.v1 ◽

2019 ◽

Author(s):

Bernardo Mantovani

Keyword(s):

Magnetic Fields ◽

Mechanism Of Action ◽

Biological Effects ◽

Low Frequency ◽

Isolated Cells ◽

Static Magnetic Fields ◽

Calcium Dependent ◽

Weak Magnetic Fields ◽

Oxidative Activation

There have been a great number of investigations about the influence of weak magnetic fields on biological systems, such as isolated cells and whole organisms. This is also a subject of considerable medical concern since old epidemiologic observations have indicated a possible tumorigenic effect of these fields. Their mechanism of action, however, is not firmly established. A large number of biological effects of electromagnetic fields have been attributed either to the production of reactive oxygen species (ROS) or to the entrance Ca2+ in the cell. A new biochemical pathway is proposed that covers these two possibilities: the primary effect of the magnetic field would be by the mechanism of radical pairs resulting in the production of ROS; these could activate the ion channels TRPM2 producing cellular inflow of Ca2+, which would induce the calcium dependent effects. Thus, a large number of biological effects observed up to the present could be explained.

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Tuning the Magnetic Alignment of Cellulose Nanocrystals from Perpendicular to Parallel Using Lepidocrocite Nanoparticles

10.26434/chemrxiv.8061839.v2 ◽

2019 ◽

Author(s):

Valentina Guccini ◽

Sugam Kumar ◽

Yulia Trushkina ◽

Gergely Nagy ◽

Christina Schütz ◽

...

Keyword(s):

Magnetic Field ◽

Magnetic Fields ◽

Cellulose Nanocrystals ◽

Small Angle Neutron Scattering ◽

Lower Amount ◽

Magnetic Alignment ◽

Polarized Optical Microscopy ◽

Parallel Orientation ◽

Weak Magnetic Fields

The magnetic alignment of cellulose nanocrystals (CNC) and lepidocrocite nanorods (LpN), pristine and in hybrid suspensions has been investigated using contrast-matched small-angle neutron scattering (SANS) under in situ magnetic fields (0 – 6.8 T) and polarized optical microscopy. The pristine CNC (diamagnetic) and pristine LpN (paramagnetic) align perpendicular and parallel to the direction of field, respectively. The alignment of both the nanoparticles in their hybrid suspensions depends on the relative amount of the two components (CNC and LpN) and strength of the applied magnetic field. In the presence of 10 wt% LpN and fields < 1.0 T, the CNC align parallel to the field. In the hybrid containing lower amount of LpN (1 wt%), the ordering of CNC is partially frustrated in all range of magnetic field. At the same time, the LpN shows both perpendicular and parallel orientation, in the presence of CNC. This study highlights that the natural perpendicular ordering of CNC can be switched to parallel by weak magnetic fields and the incorporation of paramagnetic nanoparticle as LpN, as well it gives a method to influence the orientation of LpN.<br>

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Dynamical mass generation in QED with weak magnetic fields

10.1063/1.2359274 ◽

2006 ◽

Author(s):

A. Ayala ◽

A. Bashir ◽

A. Raya ◽

E. Rojas

Keyword(s):

Magnetic Fields ◽

Mass Generation ◽

Dynamical Mass ◽

Weak Magnetic Fields ◽

Dynamical Mass Generation

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Sensitivity of PS/CoPd Janus particles to an external magnetic field

RSC Advances ◽

10.1039/d1ra02410h ◽

2021 ◽

Vol 11 (28) ◽

pp. 17051-17057

Author(s):

Anna Eichler-Volf ◽

Yara Alsaadawi ◽

Fernando Vazquez Luna ◽

Qaiser Ali Khan ◽

Simon Stierle ◽

...

Keyword(s):

Magnetic Field ◽

Magnetic Properties ◽

External Magnetic Field ◽

Magnetic Fields ◽

Janus Particles ◽

Weak Magnetic Fields

PS/CoPd Janus particles respond very sensitively to application of low external magnetic fields. Owing to the magnetic properties, the PS/CoPd particles may be used, for example, to sense the presence of weak magnetic fields as micro-magnetometers.

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