Regulation of Ribosomal Protein Synthesis in Prokaryotes

2021 ◽  
Vol 55 (1) ◽  
pp. 16-36
Author(s):  
A. O. Mikhaylina ◽  
E. Y. Nikonova ◽  
O. S. Kostareva ◽  
S. V. Tishchenko
Keyword(s):  
Protein Synthesis ◽  
Ribosomal Protein ◽  
Ribosomal Protein Synthesis

Translational regulation of ribosomal protein synthesis during xenopus development

1989 ◽  
Vol 27 ◽  
pp. 219
Author(s):  
B. Cardinali ◽  
C. Bagni ◽  
F. Amaldi ◽  
N. Campioni ◽  
P. Mariottini ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Ribosomal Protein ◽  
Translational Regulation ◽  
Xenopus Development ◽  
Ribosomal Protein Synthesis

scholarly journals Somatic uniparental disomy with a rare EFL1 variant causes Shwachman-Diamond syndrome through dysregulating ribosomal protein synthesis

2018 ◽  
Author(s):  
Sangmoon Lee ◽  
Chang Hoon Shin ◽  
Che Ry Hong ◽  
Jun-Dae Kim ◽  
Ah-Ra Kim ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Protein Synthesis ◽  
Ribosomal Protein ◽  
Rare Variant ◽  
Translational Control ◽  
Uniparental Disomy ◽  
Chromosome 15 ◽  
East Asians ◽  
Shwachman Diamond Syndrome ◽  
Ribosomal Protein Synthesis

We present three unrelated Korean Shwachman-Diamond syndrome (SDS) patients that carry an incomplete but identical homozygous EFL1 p.Thr1069Ala variant due to a bone marrow-specific mosaic uniparental disomy (UPD) in chromosome 15. This rare variant is found in 0.017% of East Asians and is asymptomatic in a heterozygous status, but harbors a hypomorphic effect, leading to 80S assembly of ribosomal protein (RP) transcripts. We propose a novel somatically-induced pathogenesis mechanism and EFL1 dysfunction that eventually leads to aberrant translational control and ribosomopathy.

Lodish model and regulation of ribosomal protein synthesis by insulin-deficient chick embryo fibroblasts

Biochemistry ◽  
1981 ◽  
Vol 20 (9) ◽  
pp. 2550-2558 ◽  
Author(s):  
George G. Ignotz ◽  
Shigeru Hokari ◽  
Robert M. DePhilip ◽  
Kinji Tsukada ◽  
Irving Lieberman
Keyword(s):  
Protein Synthesis ◽  
Chick Embryo ◽  
Ribosomal Protein ◽  
Embryo Fibroblasts ◽  
Ribosomal Protein Synthesis
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