Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome

2012 ◽  
Vol 71 (12) ◽  
pp. 2035-2043 ◽  
Author(s):  
Laura J Dickie ◽  
Azad M Aziz ◽  
Sinisa Savic ◽  
Orso M Lucherini ◽  
Luca Cantarini ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Binding Protein ◽  
Reactive Oxygen ◽  
Tumour Necrosis Factor Receptor ◽  
Periodic Syndrome ◽  
Oxygen Species ◽  
Necrosis Factor

scholarly journals Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α

1989 ◽  
Vol 263 (2) ◽  
pp. 539-545 ◽  
Author(s):  
B Meier ◽  
H H Radeke ◽  
S Selle ◽  
M Younes ◽  
H Sies ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Interleukin 1 ◽  
Human Fibroblasts ◽  
Spectral Characteristics ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Necrosis Factor Alpha ◽  
Necrosis Factor

Human fibroblasts in primary culture released reactive oxygen species upon stimulation with cytokines such as interleukin-1 alpha (IL-1) or tumour necrosis factor-alpha (TNF). The primary radical produced was O2.- as determined by e.s.r. spin trapping and cytochrome c reduction. In contrast to the oxidative burst in granulocytes and monocytes, radical formation took place continuously for at least 4 h. Low-level chemiluminescence was increased by stimulation with IL-1 and TNF. Spectral characteristics and tests with azide led to the conclusion that the photoemissive species were excited carbonyls and not singlet oxygen. Further, there was a liberation of ethane from the cells. Radical production and light emission were not altered by either xanthine or allopurinol, nor by azide, cyanide or rotenone. O2.- production increased in the presence of NADH or NADPH, making an NAD(P)H oxidase a likely source.

scholarly journals Intra-abdominal abscess in a patient with tumour necrosis factor receptor-associated periodic syndrome

2006 ◽  
Vol 259 (2) ◽  
pp. 209-213
Author(s):  
S. STJERNBERG-SALMELA ◽  
A. KIVISAARI ◽  
P. PUOLAKKAINEN ◽  
M. FARKKILA ◽  
E. KEMPPAINEN ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Receptor ◽  
Periodic Syndrome ◽  
Abdominal Abscess ◽  
Necrosis Factor

scholarly journals Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome

2015 ◽  
Vol 45 (10) ◽  
pp. 2937-2944 ◽  
Author(s):  
Lucy C. Fairclough ◽  
A. Allart Stoop ◽  
Ola H. Negm ◽  
Paul M. Radford ◽  
Patrick J. Tighe ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Receptor ◽  
Periodic Syndrome ◽  
Tnf Receptor ◽  
Necrosis Factor

Recurrent limb and facial oedema with R92Q mutation: A non-febrile late-onset tumour necrosis factor receptor-associated periodic syndrome (TRAPS)?

2013 ◽  
Vol 42 (5) ◽  
pp. 905-906
Author(s):  
Hélène Maillard-Lefebvre ◽  
Hilaire Charlanne ◽  
Pierre-Yves Hatron ◽  
Catherine Dodé ◽  
Eric Hachulla
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Late Onset ◽  
Facial Oedema ◽  
Tumour Necrosis Factor Receptor ◽  
Periodic Syndrome ◽  
Necrosis Factor
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