scholarly journals Benchmarking: the five year outcome of rheumatoid arthritis assessed using a pain score, the Health Assessment Questionnaire, and the Short Form-36 (SF-36) in a community and a clinic based sample

2001 ◽  
Vol 60 (10) ◽  
pp. 956-961 ◽  
Author(s):  
N J Wiles
Keyword(s):  
Rheumatoid Arthritis ◽  
Pain Score ◽  
Health Assessment Questionnaire ◽  
Short Form ◽  
Health Assessment ◽  
Short Form 36 ◽  
Sf 36 ◽  
Assessment Questionnaire

scholarly journals Qualidade de vida e capacidade funcional em pacientes com úlcera arterial

2016 ◽  
Vol 34 (2) ◽  
Author(s):  
Márcia Maria Renó Moreira ◽  
Fabiana Da Silva Augusto ◽  
Leila Blanes ◽  
Alfredo Gragnani ◽  
Lydia Masako Ferreira
Keyword(s):  
Health Survey ◽  
Health Assessment Questionnaire ◽  
Short Form ◽  
Health Assessment ◽  
Minas Gerais ◽  
Short Form 36 ◽  
Sf 36 ◽  
Assessment Questionnaire

Objetivo: Avaliar a Qualidade de Vida (qv) e a capacidade funcional em pacientes com Doença Arterial Periférica (dap) e Úlceras Arteriais (ua).Metodologia: Estudo clínico descritivo e transversal, realizado no Sul de Minas Gerais, Brasil. Sessenta pacientes adultos alocados em três grupos —grupo dap com ua, grupo dap sem ua e grupo controle, sem dap e sem ua— foram entrevistados,utilizando-se os questionários Health Assessment Questionnaire (haq) e o Short Form-36 Health Survey (sf-36) para medir a capacidade funcional e a qv, respectivamente. Para a comparação entre os grupos, foi utilizado o teste de Kruskal-Wallis.Resultados: Quarenta e dois participantes (70%) são mulheres e a idade média foi de 63 anos. Os pacientes com dap, com ou sem ua, apresentaram incapacidade funcional significativamente maior que pacientes sem dap (p < 0,01) nos componentes relacionados a deambulação, uso de utensílios domésticos, higiene e apreensão/sustentação de objetos. Os pacientes com dap, com ou sem lesões, apresentaram sf-36 escores significativamente mais baixos —menor qv— nos domínios Capacidade funcional, Aspectos físicos, Dorcorporal, Vitalidade, Aspectos sociais e Aspecto emocional do sf-36 em relação ao grupo controle (p < 0,001). Também foram observadas diferenças significativas (p < 0,001) entre o grupo controle e o grupo com dap e ua nos domínios Estado geral desaúde e Saúde mental.Conclusão: Os pacientes com dap, com ou sem úlcera, apresentaram redução na capacidade de realização de algumas atividades cotidianas, além de baixos níveis de qv quandocomparados aos pacientes sem a doença.

scholarly journals Validating and Assessing the Sensitivity of the Health Assessment Questionnaire-Disability Index-derived Short Form-6D in Patients with Early Aggressive Rheumatoid Arthritis

2009 ◽  
Vol 36 (6) ◽  
pp. 1150-1157 ◽  
Author(s):  
SOGOL S. AMJADI ◽  
PAUL M. MARANIAN ◽  
HAROLD E. PAULUS ◽  
ROBERT M. KAPLAN ◽  
VEENA K. RANGANATH ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Construct Validity ◽  
Health Assessment Questionnaire ◽  
Short Form ◽  
Health Assessment ◽  
Correlation Coefficients ◽  
Patient Reported ◽  
Clinical Measures ◽  
Assessment Questionnaire ◽  
Questionnaire Disability

Objective.New methodologies allow the scores for the Health Assessment Questionnaire-Disability Index (HAQ-DI) to be translated into preferences/utility scores. We evaluated the construct validity of the HAQ-DI-derived Short Form-6D (SF-6D) score and assessed its responsiveness to change over 6- and 12-month followup periods in patients with early aggressive rheumatoid arthritis (RA).Methods.Patients (n = 277) participating in an RA observational study completed self-reported measures of symptoms and the HAQ-DI at baseline and at 6 and 12 months. Total Sharp scores, C-reactive protein, and erythrocyte sedimentation rate were assessed along with clinical data. Construct validity was assessed by examining the association between SF-6D score and patient-reported and clinical measures using Spearman correlation coefficients. The responsiveness of SF-6D to change was assessed using patient and physician assessments of the disease as clinical anchors. The magnitude of responsiveness was calculated using SF-6D effect size (ES).Result.Mean SF-6D scores were 0.690, 0.720, and 0.723 at baseline and 6 and 12-month followup, respectively. Baseline patient-reported measures had moderate to high correlations with baseline SF-6D (r = 0.43 to 0.52); whereas clinical measures had negligible to low correlations with SF-6D (r = 0.001 to 0.32). ES was moderate for the groups that were deemed to have improved (ES 0.63–0.75) but negligible to small for those that did not (ES 0.13–0.46).Conclusion.Our data support the validity and responsiveness of the HAQ-DI derived SF-6D score in an early RA cohort. These results support the use of the HAQ-DI derived SF-6D in RA cohorts and clinical trials lacking preference-based measures.

Characterization of patients with chronic refractory gout who do and do not have clinically apparent tophi and their response to pegloticase

Rheumatology ◽  
2019 ◽  
Vol 58 (8) ◽  
pp. 1422-1431 ◽  
Author(s):  
N Lawrence Edwards ◽  
Jasvinder A Singh ◽  
Orrin Troum ◽  
Anthony E Yeo ◽  
Peter E Lipsky
Keyword(s):  
Health Assessment Questionnaire ◽  
Global Assessment ◽  
Short Form ◽  
Bodily Pain ◽  
Health Assessment ◽  
Serum Urate ◽  
Patient Global Assessment ◽  
Short Form 36 ◽  
Assessment Questionnaire ◽  
Questionnaire Disability

Abstract Objective To determine the characteristics and response to pegloticase of patients with chronic refractory gout with and without clinically apparent tophi. Methods Results from two randomized controlled trials of pegloticase in patients with chronic refractory gout with clinically apparent tophi or without tophi were used to assess baseline and on-treatment between-group differences. Results Patients with tophi were significantly older than those without tophi, had a significantly longer duration of disease, higher numbers of tender and swollen joints, higher Patient Global Assessment scores and Health Assessment Questionnaire-Disability Index scores, and lower Arthritis-Specific Health Index scores. Patients with tophaceous gout also had significantly lower scores for physical functioning, role physical, social functioning, and the physical component summary scores of the Short Form 36 vs patients without tophi. In addition, subjects with clinically apparent tophi had a significantly lower mean estimated glomerular filtration rate. Pegloticase treatment of tophaceous patients caused significant reductions in serum urate, flares, Patient Global Assessment, tender joints, swollen joints, Health Assessment Questionnaire-Disability Index, visual analogue scale pain and Short Form 36 Bodily Pain, whereas patients without tophi had significant improvement in serum urate, flares, Patient Global Assessment, tender joints, and Short Form 36 Bodily Pain, but not swollen joints, Health Assessment Questionnaire-Disability Index functional score or pain visual analogue scale. Treatment with pegloticase had no effect on estimated glomerular filtration rate despite significant lowering of the urinary uric acid: creatinine ratio. Conclusion Patients with chronic refractory gout and clinically apparent tophi have more severe disease as well as reduced renal function. Both groups experienced significant clinical benefit with pegloticase treatment, although no change in renal function was noted.

scholarly journals Improvement of Inflammation and Pain after Three Months’ Exclusion Diet in Rheumatoid Arthritis Patients

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3535
Author(s):  
Maria Teresa Guagnano ◽  
Chiara D’Angelo ◽  
Daniela Caniglia ◽  
Pamela Di Giovanni ◽  
Eleonora Celletti ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Short Form ◽  
Health Assessment ◽  
Systemic Autoimmune Disease ◽  
Physical And Mental Health ◽  
Reactive Protein ◽  
Balanced Diet ◽  
Sf 36 ◽  
Assessment Questionnaire

Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease affecting the synovial joints and causing severe disability. Environmental and lifestyle factors, including diet, have been proposed to play a role in the onset and severity of RA. Dietary manipulation may help to manage the symptoms of RA by lowering inflammation and potentially decreasing pain. Methods: In 40 patients with long-standing RA with stable symptoms and treated with conventional (c-) and biological (b-) disease modifying anti-rheumatic drugs (DMARDs), the effect of a 3-month diet avoiding meat, gluten, and lactose (and all dairy products; privative diet) was evaluated in comparison with a control balanced diet including those foods. Both diets were designed to reduce weight since all patients were overweight or obese. Patients were randomly assigned to one of the diets, and RA was clinically assessed at Time 0 (T0), through the Visual Analogue Scale (VAS), for pain, and the Disease Activity Score of 28 joints (DAS 28) for RA activity. Patients were also administered the Short Form Health survey (SF-36) and the Health Assessment Questionnaire (HAQ). At T0, a blood sample was collected for laboratory tests and adipokines measurements, and anthropometric measurements were compared. These evaluations were repeated at the end of the 3 months’ dietary regimens. Results: A significant decrease in VAS and the improvement of the overall state of physical and mental health, assessed through SF-36, was observed in patients assigned to the privative diet. Both dietary regimens resulted in the improvement of quality of life compared to baseline values; however, the change was significant only for the privative diet. With either diet, patients showed significant decreases in body weight and body mass index, with a reduction in waist and hips circumference and lower basal glucose and circulating leptin levels. A privative diet was also able to significantly reduce systolic (p = 0.003) and diastolic (p = 0.025) arterial pressure. The number of circulating leukocytes and neutrophils, and the level of hs-C-Reactive Protein also decreased after 3 months of the meat-, lactose-, and gluten-free diet. Conclusions: Our results suggest that a privative diet can result in a better control of inflammation in RA patients under stable optimized drug treatment.

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