scholarly journals Retinoblastoma in an adult: a diagnostic dilemma

2019 ◽  
Vol 12 (10) ◽  
pp. e230537
Author(s):  
Ritika Mukhija ◽  
Neiwete Lomi ◽  
Saumya Kumar ◽  
Seema Sen
Keyword(s):  
Choroidal Melanoma ◽  
Emission Tomography ◽  
Positron Emission Tomography Scan ◽  
Provisional Diagnosis ◽  
Diagnostic Dilemma ◽  
Positron Emission ◽  
Poorly Differentiated ◽  
Anterior Choroidal ◽  
The Right ◽  
Tomography Scan

We report a case of a man aged 35 years who presented with the chief complaint of painless diminution of vision in the right eye for 4 months. Examination revealed a large inferior retinochoroidal mass along with retinal detachment. An anterior choroidal mass with moderate internal reflectivity was seen on B-scan ocular ultrasonography and MRI and CT scan were indicative of a mitotic aetiology. Fluorodeoxyglucose-positron emission tomography scan ruled out any other systemic foci of involvement. Based on the above findings, a provisional diagnosis of amelanotic choroidal melanoma was made and he was taken up for choroidal aspiration biopsy, wherein the cytopathology report revealed hypercellularity with no identifiable pigments. In view of the above, a diagnosticandtherapeutic enucleation was performed; however, the histopathology report of the enucleated specimen revealed poorly differentiated retinoblastoma. This case highlights that the diagnosis of retinoblastoma should be kept in mind even in adult patients.

Cording in Disseminated Mycobacterium chelonae Infection in an Immunocompromised Patient

2020 ◽  
Author(s):  
Gregory Olson ◽  
Moira C McNulty ◽  
Kathleen Mullane ◽  
Kathleen G Beavis ◽  
Vera Tesic
Keyword(s):  
Positron Emission Tomography ◽  
Immunocompromised Patient ◽  
Left Lung ◽  
Emission Tomography ◽  
Positron Emission Tomography Scan ◽  
Mycobacterium Chelonae ◽  
Positron Emission ◽  
Lung Biopsies ◽  
The Right ◽  
Tomography Scan

Abstract Cording is a phenomenon in which acid fast bacilli grow in parallel and was previously used as a means of presumptive microscopic identification of Mycobacterium tuberculosis (TB). However, this process has been shown in multiple other nontuberculous mycobacterial (NTM) species. Here we present the case of an immunocompromised adult who presented with wrist pain, weight loss, and cough. A positron emission tomography scan showed uptake in the right ulna, multiple soft tissue sites, and the left lung. Biopsies and cultures were obtained from multiple sites, and the patient was ultimately diagnosed with disseminated Mycobacterium chelonae infection. The organism showed cording in culture. As seen in this patient, cording may occur in multiple NTM species and is not reliable as the sole indicator of the presence of TB.

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