scholarly journals Making an objective diagnosis of tetanus—utility of a simple neurophysiological test

2019 ◽  
Vol 12 (12) ◽  
pp. e232344 ◽  
Author(s):  
Hina Imtiaz ◽  
Haris Hakeem ◽  
Anusha Alam ◽  
Dureshahwar Kanwar

Tetanus remains a significant cause of mortality especially in the developing world. Early diagnosis and institution of treatment is critical to prevent fatal complications. The diagnosis is made on clinical grounds, which may sometimes be difficult, especially in case of localised tetanus. Being able to diagnose tetanus objectively is invaluable in such cases. In this regard, masseter inhibitory reflex (MIR) is a simple neurophysiological test that can be performed at the bedside. Herein, we report a case of craniocervical tetanus that was objectively diagnosed using MIR and adequately treated.

2022 ◽  
Vol 1 ◽  
pp. 21-23
Author(s):  
K. S. Lakshmi Srividya ◽  
Vidyasagar P

Angioedema is a transient, non-pitting oedema that involves subcutaneous or submucosal tissue. Angioedema in children can have varied aetiology and clinical manifestations, unlike that in adults. We report a case of angioedema of penis in a child resulting from insect bite and treated successfully with anti-histamine and leukotriene inhibitor. Penile angioedema should be kept in mind as a differential diagnosis of penile swelling, as early diagnosis and management may prevent fatal complications.


2016 ◽  
Vol 23 (3) ◽  
pp. 63-70
Author(s):  
L. K Mikhailova ◽  
T. V Sokolova ◽  
O. A Polyakova

Mucopolysaccharidosis (MPS) is an orphan pathology characterized by polymorphism of clinical manifestations and development of typical skeletal changes. However in early childhood the clinical picture is not clear that leads to misdiagnosis and results in inadequate management of patients including unjustified surgical intervention. Early clinical and roentgenologic changes specific to mucopolysaccharidosis IV and VI that enable to suspect the pathology development, to perform required examination with compulsory confirmation by DNA testing results and prescribe vital enzyme replacement therapy as soon as possible are presented. Early diagnosis and initiation of etiotropic treatment and timely correction of the occurring pathology ensure prevention of fatal complications.


1992 ◽  
Vol 74 (6) ◽  
pp. 727-732 ◽  
Author(s):  
R.H. Groot ◽  
B.W. Ongerboer de Visser ◽  
J.P.R. van Merkesteyn ◽  
J.D. Speelman ◽  
J. Bras

2003 ◽  
Vol 114 (7) ◽  
pp. 1253-1258 ◽  
Author(s):  
E Gastaldo ◽  
A Graziani ◽  
M Paiardi ◽  
R Quatrale ◽  
R Eleopra ◽  
...  

2013 ◽  
Vol 24 (2) ◽  
pp. 692-694
Author(s):  
Enrico Nastro Siniscalchi ◽  
Luciano Catalfamo ◽  
Salvatore Crimi ◽  
Francesca Rinaldo ◽  
Vincenzo Rizzo ◽  
...  

Brain ◽  
1990 ◽  
Vol 113 (3) ◽  
pp. 781-792 ◽  
Author(s):  
B. W. ONGERBOER DE VISSER ◽  
G. CRUCCU ◽  
M. MANFREDI ◽  
J. H. TH. M. KOELMAN

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