scholarly journals Massive pulmonary embolism following recovery from COVID-19 infection: inflammation, thrombosis and the role of extended thromboprophylaxis

2020 ◽  
Vol 13 (9) ◽  
pp. e238168
Author(s):  
Prakash Vadukul ◽  
Deepak S Sharma ◽  
Paul Vincent

COVID-19 is the infectious disease caused by a recently discovered SARS-CoV-2. Following an initial outbreak in December 2019 in Wuhan, China, the virus has spread globally culminating in the WHO declaring a pandemic on 11 March 2020. We present the case of a patient with an initial presentation of COVID-19 pneumonitis requiring mechanical ventilation for nearly 2 weeks and total admission time of 3 weeks. She was given prophylactic dose anticoagulation according to hospital protocol during this time. Following a week at home, she was readmitted with acute massive pulmonary embolism with severe respiratory and cardiac failure, representing the first such case in the literature.

2018 ◽  
Vol 19 ◽  
pp. 1541-1545
Author(s):  
Anam M. Elarabi ◽  
Eman Mosleh ◽  
Laith I. Alamlih ◽  
Mutaz M. Albakri ◽  
Wanis H. Ibrahim

1997 ◽  
Vol 14 (3) ◽  
pp. 277-281 ◽  
Author(s):  
KEVIN M. HARRIS ◽  
J. CAMERON MUIR ◽  
MICHAEL F. HANEY ◽  
JONATHAN F. PLEHN

1975 ◽  
Vol 89 (4) ◽  
pp. 413-418 ◽  
Author(s):  
Joseph S. Alpert ◽  
Roger E. Smith ◽  
Ira S. Ockene ◽  
Joseph Askenazi ◽  
Lewis Dexter ◽  
...  

2015 ◽  
Vol 3 (4) ◽  
Author(s):  
Lexin Wang

Pulmonary embolism is a common disease that is associated with significant mobility and mortality. Thrombolysis is potentially life saving when used in conjunction with anticoagulant therapy. Indications for thrombolysis for pulmonary embolism are not well defined. In patients with acute massive pulmonary embolism and hypotension, thrombolytic therapy offers some benefits in terms of mortality reduction. The use of thrombolysis in patients with stable haemodynamics has been controversial for more than two decades. Recent clinical studies have indicated that thrombolytic treatment in conjunction with heparin in patients with submassive pulmonary embolism and normal blood pressure can prevent deterioration of the disease and diminish the need for more intensive therapies during hospitalisation. The role of prehospital thrombolytic therapy for acute pulmonary embolism is unclear and further clinical studies are warranted.


2010 ◽  
Vol 5 (6) ◽  
pp. 716-721 ◽  
Author(s):  
Dabit Arzamendi ◽  
Luc Bilodeau ◽  
Reda Ibrahim ◽  
Stephane Noble ◽  
Richard Gallo ◽  
...  

2012 ◽  
Vol 15 (1) ◽  
pp. 56
Author(s):  
Michael S. Firstenberg ◽  
Erik Abel ◽  
Robert S. D. Higgins ◽  
John H. Sirak ◽  
Chittoor B. Sai-Sudhakar ◽  
...  

We present a case of a patient who underwent successful concomitant surgical management of his massive pulmonary embolism and severe multivessel coronary disease. His presentation with shortness of breath prompted a comprehensive evaluation, which revealed both problems. This experience emphasizes the importance of considering both problems, because treating one but not the other could be catastrophic.


2004 ◽  
Vol 27 (3) ◽  
pp. 175-178
Author(s):  
Andrew D. Sumner ◽  
Rick Henderson ◽  
Deena Martin ◽  
Vincent L. Sorrell

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