Idiopathic spontaneous haemoperitoneum at 4 weeks gestation

2021 ◽  
Vol 14 (9) ◽  
pp. e244470
Author(s):  
Emily O'Brien ◽  
Rehan Feroz ◽  
Sona Jasani

A 20-year-old nulliparous patient with acute-onset abdominal pain and imaging suggestive of haemoperitoneum was admitted for observation. Though, initially, haemodynamically stable, her clinical picture worsened throughout her hospitalisation and warranted two separate laparoscopies that revealed 1200 mL and 50 mL of haemoperitoneum, respectively, without an identifiable bleeding source. After serial β-human chorionic gonadotropin levels and ultrasound confirmation of a viable pregnancy 23 days later, the patient underwent a normal antenatal course and delivered a healthy infant at 37 weeks gestation. This unusual case highlights the need to consider spontaneous haemoperitoneum in pregnancy as a diagnosis, particularly in the setting of pregnancy of unknown location, even at an early stage of pregnancy.

Neurosurgery ◽  
1989 ◽  
Vol 24 (4) ◽  
pp. 579-583 ◽  
Author(s):  
Tatsuya Kobayashi ◽  
Jun Yoshida ◽  
Yoshihisa Kida

ABSTRACT Two cases of a human chorionic gonadotropin-producing germ cell tumor originating bilaterally in the basal ganglia and thalamus are reported. The biological behavior and clinical characteristics were similar to those of unilateral germinomas involving the basal ganglia and thalamus. Common clinical features were slowly progressive unilateral pyramidal signs and bilateral and/or unilateral extrapyramidal signs which occurred either concomitantly or sequentially. Bilateral symmetrical lesions were demonstrated by computed tomography and/or magnetic resonance imaging at an early stage of illness. Serum and cerebrospinal fluid human chorionic gonadotropin levels were elevated (116 and 141 mIU/ml, respectively) but decreased and remained within normal limits after radiation therapy alone. Radiosensitivity was confirmed by repeated computed tomographic scans and tumor marker measurements. Multiple concomitant germ cell tumors is a rare, but interesting lesion, especially considering its pathogenesis and oncogenesis.


2011 ◽  
Vol 412 (17-18) ◽  
pp. 1515-1520 ◽  
Author(s):  
Martina Montagnana ◽  
Tommaso Trenti ◽  
Rosalia Aloe ◽  
Gianfranco Cervellin ◽  
Giuseppe Lippi

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