Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carcinoma

2021 ◽  
Vol 14 (12) ◽  
pp. e245746
Author(s):  
Barbara Verro ◽  
Carmelo Saraniti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Basaloid Squamous Cell Carcinoma ◽  
Neck Node ◽  
History Of ◽  
Node Metastases ◽  
Basaloid Squamous

A 71-year-old man presented to our otolaryngology clinic with dysphagia and dyspnoea. He had a history of smoking for 40 years. Laryngoscopy showed an exophytic, round mass on the left aryepiglottic fold that was entirely excised by transoral laser CO2 microsurgery. Histological assessment revealed a pT1 basaloid squamous cell carcinoma (BSCC) with free-margin resection. He underwent close follow-up and after 3-year follow-up, the patient was free from disease. Laryngeal BSCC is a rare cancer with poor prognosis due to its late diagnosis and early neck node metastases. We report a rare case of early tumour treated by endoscopic surgery without complications or recurrence of disease. However, knowing this type of cancer and making a correct differential diagnosis are important to guarantee the best therapy and prognosis.

Unusual metastatic localization to the kidney of basaloid squamous cell carcinoma of the oropharynx

2018 ◽  
Vol 85 (4) ◽  
pp. 182-185
Author(s):  
Costantino Ricci ◽  
Martina S Rossi ◽  
Roberta De Stefano ◽  
Michelangelo Fiorentino ◽  
Francesco Vasuri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Surgical Excision ◽  
Renal Lesion ◽  
Basaloid Squamous Cell Carcinoma ◽  
Case Presentation ◽  
History Of ◽  
Node Metastases ◽  
Basaloid Squamous

Case presentation: A 55-year-old man with a history of basaloid squamous cell carcinoma of the oropharynx with laterocervical lymph node metastases 6 years before (and treated with chemoradiation) presented with flank pain and hematuria. Computed tomography scan found a renal lesion, with radiological features more suspicious for primitive renal neoplasia. Histopathological and immunohistochemical examination after surgical excision revealed a basaloid squamous cell carcinoma involving renal parenchyma. Conclusion: Basaloid squamous cell carcinoma is a rare tumor but with a high percentage of distant metastasis, and it is mandatory, also for a general pathologist, to know this disease. Moreover, in a patient with renal metastases, any type of cancer should be taken into account, and this case is emblematic of why the previous medical history is crucial for differential diagnosis.

Basaloid Squamous Cell Carcinoma of the Larynx and Hypopharynx

1997 ◽  
Vol 106 (12) ◽  
pp. 1024-1035 ◽  
Author(s):  
Alfio Ferlito ◽  
Alessandra Rinaldo ◽  
Giuseppe Altavilla ◽  
Claudio Doglioni
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Lymph Node ◽  
Basaloid Squamous Cell Carcinoma ◽  
Cervical Lymph Node Metastases ◽  
Node Metastases ◽  
Basaloid Squamous

Basaloid squamous cell carcinoma (BSCC) is a recently described bimorphic variant of squamous cell carcinoma with distinct morphological and biological features. We describe the clinicopathological findings, along with immunohistochemical and ultrastructural investigations, in 15 new cases of BSCC of the larynx or hypopharynx observed and treated at the otolaryngology department of the University of Padua between 1989 and 1995. The world literature is also reviewed in order to develop a more accurate clinicopathological profile of the tumor. Patient records and histologic slides were reviewed in all of our 15 cases. The patient group consisted of 13 men (86.67%) and 2 women with a mean age of 63.33 years (median 69 years; range 44 to 84 years). Nine patients presented with cervical lymph node metastases. Surgical treatment was the therapy of choice; radiotherapy and chemotherapy have been applied in different combinations. Follow-up was available on all 15 cases. Local recurrence was described in 3 cases. Five of the 9 patients with cervical lymph node metastases developed distant metastases. Distant spread of the tumor without lymph node involvement was observed during follow-up in 4 cases. Nine patients died of disease, 2 are alive with widespread metastases, 2 are alive with no evidence of disease, and 2 have died of other causes. The determined 5-year survival was estimated to be 17.5% by the Kaplan-Meier method. In conclusion, BSCC is a distinctive carcinoma that is important to recognize, because it has a more aggressive biological behavior than conventional squamous cell carcinoma.

scholarly journals A Case of Basaloid Squamous Cell Carcinoma of Polypoid Type in the Esophagus

2017 ◽  
Vol 11 (3) ◽  
pp. 559-563
Author(s):  
Ki Hun Lee ◽  
Sang Jin Lee ◽  
Hak Soo Kim ◽  
Sung Eun Kim ◽  
Soo Yong Choi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Endoscopic Examination ◽  
Basaloid Squamous Cell Carcinoma ◽  
Polypoid Mass ◽  
Carcinoma Of The Esophagus ◽  
Ivor Lewis ◽  
Basaloid Squamous

Basaloid squamous cell carcinoma of the esophagus is very rare. Further, polypoid type of esophageal cancer is also rare. We have recently treated a case of basaloid squamous cell carcinoma which presented as a 1.3-cm esophageal polyp. A 48-year-old woman was referred to our hospital because of a polypoid mass at 36 cm distance from the upper incisor on endoscopic examination, and the result of the biopsy was basaloid squamous cell carcinoma. The patient underwent Ivor Lewis operation with lymph node dissection. Two basaloid squamous cell carcinomas, of 1.3 and 0.4 cm, were diagnosed in the final pathologic examination. Regular periodic follow-up showed no evidence of recurrence or metastasis in the 5-month postoperative period.

scholarly journals Coexistence of Basaloid Squamous Cell Carcinoma and Large Cell Neuroendocrine Carcinoma in the Larynx: A Case Report and Literature Review

2020 ◽  
pp. 014556132095647
Author(s):  
Sanchun Wang ◽  
Hongyan Fang ◽  
Weifang Tong ◽  
Hongyan Wang ◽  
Bo Teng
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neuroendocrine Carcinoma ◽  
Squamous Cell ◽  
Large Cell ◽  
Large Cell Neuroendocrine Carcinoma ◽  
Basaloid Squamous Cell Carcinoma ◽  
Transoral Microsurgery ◽  
Basaloid Squamous

Basaloid squamous cell carcinoma and large cell neuroendocrine carcinoma are not common in head and neck, these tumors rarely occur in the larynx but both have highly aggressive clinical behavior and a high mortality rate. The diagnosis is complicated by these tumors’ atypical clinical and pathological features. This case details a coexistence of basaloid squamous cell carcinoma and large cell neuroendocrine carcinoma of a woman in the larynx. The patient underwent endoscopy- and coblation-assisted transoral microsurgery to achieve hyoid horizontal epiglottidectomy and has no recurrence after 12 months of follow-up.

Subcutaneous metastasis from recurrent basaloid squamous cell carcinoma of the esophagus

2017 ◽  
Vol 25 (2) ◽  
pp. 492-496
Author(s):  
Sonam Puri ◽  
Lisa M Holle ◽  
Faripour A Forouhar ◽  
Jessica M Clement
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Recurrent Disease ◽  
Basaloid Squamous Cell Carcinoma ◽  
Carcinoma Of The Esophagus ◽  
Subcutaneous Nodules ◽  
History Of ◽  
Basaloid Squamous

Background Esophageal cancer is the 11th most common cause of cancer mortality in the United States. It is aggressive in nature and has an ability to spread rapidly through direct extension, lymphatic spread, or hematogenously. With an estimated incidence of 1%, cutaneous metastases from esophageal cancer are extremely rare. Case presentation In this case study and review, we describe a case of recurrent esophageal basaloid squamous cell carcinoma presenting as multiple, rapidly progressing and tender subcutaneous nodules. A 69-year-old male with history of basaloid squamous cell carcinoma of the esophagus treated with concurrent chemoradiation, presented to his oncologist with complaints of a large, painful nodule at the nape of his neck approximately two years after completing treatment. On further examination, he was noted to have multiple, well circumscribed, solid, tender nodules on his abdominal wall along with a painful nodule on the pulp of his index finger. Histopathology from all sites revealed skin infiltration by high-grade invasive basaloid subtype of squamous cell carcinoma, similar to patient’s prior known and treated primary esophageal cancer. Further imaging work up showed extensive metastatic disease involving lung, liver, and brain. Conclusion Esophageal squamous cell carcinoma rarely metastasize to the skin. Subcutaneous nodules can be the first presentation of recurrent disease. The lesions are commonly confused with skin infections and treated inappropriately with antibiotics, leading to delay in diagnosis of recurrent disease. Early biopsy of suspicious lesions should be performed, especially in patients with history of cancer, such that prompt diagnosis and treatment can occur to maximize patient outcomes.

scholarly journals Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Kumiko Sekiguchi ◽  
Takeshi Matsutani ◽  
Tsutomu Nomura ◽  
Nobutoshi Hagiwara ◽  
Akihisa Matsuda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Pulmonary Metastasectomy ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous
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