scholarly journals Routine Induction of Labour by Amniotomy and Simultaneous Syntocinon (Synthetic Oxytocin) Infusion

BMJ ◽  
1970 ◽  
Vol 3 (5716) ◽  
pp. 191-193 ◽  
Author(s):  
M. E. Pawson ◽  
S. C. Simmons
Keyword(s):  
Induction Of Labour ◽  
Oxytocin Infusion ◽  
Synthetic Oxytocin

Prolonged pregnancy

2020 ◽  
pp. 389-394
Author(s):  
Kate F. Walker ◽  
Jim G. Thornton
Keyword(s):  
Caesarean Section ◽  
Pregnancy Loss ◽  
Expectant Management ◽  
Induction Of Labour ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Increased Risk ◽  
Oxytocin Infusion ◽  
Prolonged Pregnancy ◽  
Overall Risk

Prolongation of gestation beyond 42+0 weeks (or 294 days) affects about 6% of pregnancies. It is associated with an increased risk of perinatal morbidity and mortality; the overall risk of pregnancy loss (stillbirth plus death occurring up to the age of 1 year) increases eightfold between 37 weeks and 43 weeks. Since trials comparing induction of labour with expectant management suggest that induction does not increase the rate of caesarean section, many clinicians offer it for pregnancies beyond 41 weeks. Induction of labour is usually performed using prostaglandin ripening followed, if necessary, by amniotomy and oxytocin infusion.

What is best practice for oxytocin infusion for induction of labour?

2001 ◽  
Vol 175 (6) ◽  
pp. 336-337
Author(s):  
Elizabeth Burrows ◽  
Jeremy N Anderson ◽  
Kerrie Papacostas
Keyword(s):  
Best Practice ◽  
Induction Of Labour ◽  
Oxytocin Infusion

The effect of oxytocin administration upon the pulsatile secretion of luteinizing hormone in humans

1989 ◽  
Vol 121 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Janet A. Amico ◽  
Donald W. Richardson ◽  
Stephen J. Winters
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Follicular Phase ◽  
The Other ◽  
Healthy Men ◽  
Pulsatile Secretion ◽  
Oxytocin Infusion ◽  
Double Blinded ◽  
Lh Secretion ◽  
Synthetic Oxytocin

Abstract. The effect of iv administration of synthetic oxytocin upon the pulsatile pattern of LH secretion was studied in 5 healthy men and 10 healthy women. Five of the women were studied in the follicular phase of a menstrual cycle and the other 5 were studied in the luteal phase of a cycle. Synthetic oxytocin in 0.9% saline or saline alone was administered via continuous iv infusion for 8 h on 2 consecutive days. Infusions were administered using a double-blinded and radomized schedule. The rate of the oxytocin infusion commenced at 1 mU/min and was increased 1 mU/min every 40 min to a final rate of 12 mU/min. The plasma oxytocin concentration during oxytocin infusion ranged from 2–70 fmol/l. Blood for LH determination was sampled every 20 min in the 5 follicular phase women and every 10 min in the 5 men and 5 luteal phase women. The detect algorithm was used to analyze LH pulsatile secretion. Oxytocin infusion was without significant effect on mean LH, number of LH pulses, or area under the LH curve in men or women studied for the period of observation. Thus it is unlikely that increases in plasma oxytocin regulate the pulsatile secretion of LH in humans.

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