Correction: Maternal smoking during pregnancy and offspring body composition in adulthood: results from two birth cohort studies

ObjectiveTo evaluate the association of maternal smoking during pregnancy with offspring body composition in adulthood and explore the causality of this association.DesignBirth cohort.SettingPopulation-based study in Pelotas, Brazil.ParticipantsAll newborn infants in the city’s hospitals were enrolled in 1982 and 1993. At a mean age of 30.2 and 22.6 years, the 1982 and 1993 cohorts, respectively, followed the subjects and 7222 subjects were evaluated.Primary outcome measuresBody mass index (BMI), fat mass index, android to gynoid fat ratio, waist circumference, waist to height ratio, lean mass index and height.ResultsPrevalence of maternal smoking during pregnancy was 35.1% and 32.6%, in 1982 and 1993 cohorts, respectively. Offspring of smoking mothers showed higher mean BMI (β: 0.84; 95% CI: 0.55 to 1.12 kg/m2), fat mass index (β: 0.44; 95% CI: 0.23 to 0.64 kg/m2), android to gynoid fat ratio (β: 0.016; 95% CI: 0.010 to 0.023), waist circumference (β: 1.74; 95% CI: 1.15 to 2.33 cm), waist to height ratio (β: 0.013; 95% CI: 0.010 to 0.017) and lean mass index (β: 0.33; 95% CI: 0.24 to 0.42 kg/m2), whereas height was lower (β: −0.95; −1.26 to −0.65). Weight gain in the first 2 years captured most of the association of maternal smoking with BMI (96.2%), waist circumference (86.1%) and fat mass index (71.7%).ConclusionsMaternal smoking in pregnancy was associated with offspring body composition measures in adulthood.

Download Full-text

Intrauterine exposure to smoking and wheezing in adolescence: the 1993 Pelotas Birth Cohort

Journal of Developmental Origins of Health and Disease ◽

10.1017/s2040174414000555 ◽

2014 ◽

Vol 6 (3) ◽

pp. 217-224 ◽

Cited By ~ 2

Author(s):

F. C. Werhmeister ◽

B. P. Nunes ◽

C. Loret de Mola ◽

N. Gómez-Cofré ◽

P. D. de Oliveira ◽

...

Keyword(s):

Birth Cohort ◽

Maternal Smoking ◽

Demographic Variables ◽

Respiratory Morbidity ◽

Asthma Diagnosis ◽

Smoking During Pregnancy ◽

Live Births ◽

Asthma Symptoms ◽

High Prevalence ◽

Maternal Smoking During Pregnancy

Previous studies have suggested an association between maternal smoking during pregnancy and asthma symptoms such as wheezing during childhood. However, few have evaluated this association in adolescence, especially in populations with high prevalence of wheezing as in Brazil. Using the 1993 Pelotas birth cohort, a longitudinal study set in southern Brazil of 5249 urban live births, we aimed to evaluate the association between maternal and the partner’s smoking during pregnancy and wheezing at 11 and 15 years of age. We evaluated smoking during pregnancy using number of cigarettes/day, and our main outcomes were as follows: wheezing in the last year and number of wheezing crises, at both 11 and 15 years of age, as well as persistent wheezing (having crises at 11 and 15 years of age) and medical asthma diagnosis at age 15. In addition, other socio-demographic variables were included as possible confounders and mediators of this association. We used Poisson regression models to evaluate crude and adjusted associations. Of the 5249 live births in 1993, 87.5% and 85.7% were followed-up to 11 and 15 years of age, respectively. Maternal smoking during pregnancy showed a dose-response association with number of wheezing crises at age 15 (P=0.023), presence of persistent wheezing (P=0.034) and asthma diagnosis (P=0.023). Partner’s smoking was not associated with any wheezing variables. Maternal smoking during pregnancy appears to exert an effect on respiratory morbidity of adolescents, evaluated by wheezing symptoms.

Download Full-text

Does maternal smoking during pregnancy predict the smoking patterns of young adult offspring? A birth cohort study

Tobacco Control ◽

10.1136/tc.2006.016790 ◽

2006 ◽

Vol 15 (6) ◽

pp. 452-457 ◽

Cited By ~ 60

Author(s):

A. Al Mamun ◽

F. V O'Callaghan ◽

R. Alati ◽

M. O'Callaghan ◽

J. M Najman ◽

...

Keyword(s):

Cohort Study ◽

Young Adult ◽

Birth Cohort ◽

Maternal Smoking ◽

Birth Cohort Study ◽

Adult Offspring ◽

Smoking During Pregnancy ◽

Smoking Patterns ◽

Maternal Smoking During Pregnancy

Download Full-text

Effects of maternal smoking during pregnancy on body composition in offspring

Pediatrics International ◽

10.1111/j.1442-200x.2011.03383.x ◽

2011 ◽

Vol 53 (6) ◽

pp. 851-857 ◽

Cited By ~ 15

Author(s):

Toshihiro Ino ◽

Tomoyuki Shibuya ◽

Kota Saito ◽

Tetsuya Ohtani

Keyword(s):

Body Composition ◽

Maternal Smoking ◽

Smoking During Pregnancy ◽

Maternal Smoking During Pregnancy

Download Full-text

Maternal Smoking During Pregnancy and ADHD: Results From a Systematic Review and Meta-Analysis of Prospective Cohort Studies

Journal of Attention Disorders ◽

10.1177/1087054717696766 ◽

2017 ◽

Vol 24 (12) ◽

pp. 1637-1647 ◽

Cited By ~ 14

Author(s):

Yan He ◽

Jian Chen ◽

Li-Hua Zhu ◽

Ling-Ling Hua ◽

Fang-Fang Ke

Keyword(s):

Cohort Studies ◽

Prospective Cohort ◽

Maternal Smoking ◽

Meta Analysis ◽

Smoking During Pregnancy ◽

Prospective Cohort Studies ◽

Relative Risks ◽

Increased Risk ◽

Quitting Smoking ◽

Maternal Smoking During Pregnancy

Objective: Findings on maternal smoking during pregnancy and ADHD risk in children are inconsistent. A meta-analysis was performed to summarize effects of exposure to maternal smoking during pregnancy on ADHD risk in children. Method: We conducted a systematic literature search to select articles up to June 2016. Only prospective cohort studies were included. Summary relative risks (RRs) with 95% confidence intervals (CIs) were calculated. Results: Pooled RR estimates based on 12 cohort studies including 17,304 pregnant women suggested that maternal smoking during pregnancy was associated with an increased risk of ADHD (pooled RR = 1.58, 95% CI = [1.33, 1.88]). Conclusion: Results from this study indicate that maternal smoking during pregnancy is related to an increased risk of ADHD in children. There is an urgent need to increase maternal awareness of smoking risk and quitting smoking to mitigate the ADHD risk in children.

Download Full-text