Radiation therapy in malignant spinal cord compression: what is the current knowledge on fractionation schedules? A systematic literature review

2012 ◽  
Vol 2 (1) ◽  
pp. 51-56
Author(s):  
Erik Torbjørn Løhre ◽  
Jo-Åsmund Lund ◽  
Stein Kaasa
2019 ◽  
Vol 28 (17) ◽  
pp. S24-S29
Author(s):  
Rebecca Troke ◽  
Tanya Andrewes

Background: metastatic spinal cord compression (MSCC) is an oncology emergency. Prevalence is increasing. Treatment and care are complex and those diagnosed may be faced with life-changing challenges. Aims: to review the impact and management of MSCC in patients with cancer, in order to analyse nursing considerations for supporting patients. Methods: a literature review and thematic analysis of five primary research papers, published between 2009 and 2014. Findings: two themes of prognosis/survival time and independence versus dependence were discovered. Conclusions: the onset of MSCC may result in paralysis and associated loss of independence, impacting on a patient's quality of life. Understanding individuals' prognosis and treatment/care preferences is fundamental for the sensitive, individualised support of patients with MSCC. The findings reinforce the nurses' role in health education, in order to raise awareness of MSCC and promote early diagnosis so that patients maintain function and independence as long as possible. The findings support the need for nurses to be equipped with appropriate communication skills to initiate and engage in sensitive, difficult and proactive conversations with patients and their families, supporting the delivery of humanised care.


2020 ◽  
Vol 106 (4) ◽  
pp. 780-789 ◽  
Author(s):  
Dirk Rades ◽  
Jon Cacicedo ◽  
Antonio J. Conde-Moreno ◽  
Barbara Segedin ◽  
Jasna But-Hadzic ◽  
...  

2019 ◽  
Vol 9 (1_suppl) ◽  
pp. 98S-107S ◽  
Author(s):  
Ori Barzilai ◽  
Stefano Boriani ◽  
Charles G. Fisher ◽  
Arjun Sahgal ◽  
Jorrit Jan Verlaan ◽  
...  

Study Design: Literature review. Objective: To provide an overview of the recent advances in spinal oncology, emphasizing the key role of the surgeon in the treatment of patients with spinal metastatic tumors. Methods: Literature review. Results: Therapeutic advances led to longer survival times among cancer patients, placing significant emphasis on durable local control, optimization of quality of life, and daily function for patients with spinal metastatic tumors. Recent integration of modern diagnostic tools, precision oncologic treatment, and widespread use of new technologies has transformed the treatment of spinal metastases. Currently, multidisciplinary spinal oncology teams include spinal surgeons, radiation and medical oncologists, pain and rehabilitation specialists, and interventional radiologists. Consistent use of common language facilitates communication, definition of treatment indications and outcomes, alongside comparative clinical research. The main parameters used to characterize patients with spinal metastases include functional status and health-related quality of life, the spinal instability neoplastic score, the epidural spinal cord compression scale, tumor histology, and genomic profile. Conclusions: Stereotactic body radiotherapy revolutionized spinal oncology through delivery of durable local tumor control regardless of tumor histology. Currently, the major surgical indications include mechanical instability and high-grade spinal cord compression, when applicable, with surgery providing notable improvement in the quality of life and functional status for appropriately selected patients. Surgical trends include less invasive surgery with emphasis on durable local control and spinal stabilization.


2018 ◽  
Vol 115 ◽  
pp. e681-e687 ◽  
Author(s):  
Federico Pessina ◽  
Pierina Navarria ◽  
Giulio Alberto Carta ◽  
Giuseppe Roberto D'Agostino ◽  
Elena Clerici ◽  
...  

2020 ◽  
Vol 9 (4) ◽  
pp. 1370-1374
Author(s):  
James E. Han ◽  
Robert H. Press ◽  
Shaakir Hasan ◽  
J. Isabelle Choi ◽  
Charles B. Simone II

Spine ◽  
2012 ◽  
Vol 37 (1) ◽  
pp. 78-84 ◽  
Author(s):  
Jaehon M. Kim ◽  
Elena Losina ◽  
Christopher M. Bono ◽  
Andrew J. Schoenfeld ◽  
Jamie E. Collins ◽  
...  

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