Antibiotic prophylaxis of endocarditis: new recommendations

1990 ◽  
Vol 28 (23) ◽  
pp. 90-91
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Prophylaxis ◽  
Antimicrobial Chemotherapy ◽  
Working Party ◽  
British Society ◽  
General Anaesthetic ◽  
Oral Doses ◽  
Erythromycin Stearate ◽  
Gram Positive Cocci ◽  
Dental Work

The Endocarditis Working Party of the British Society for Antimicrobial Chemotherapy has recently updated its recommendations for the antibiotic prophylaxis of infective endocarditis (Endocarditis Working Party, BSAC, Lancet 1990; 335: 88–89). This follows reports of nausea after large oral doses of erythromycin stearate, previously recommended for patients allergic to penicillin who are having dental work without a general anaesthetic. An alternative, clindamycin is now introduced. This antibiotic is very active against Gram-positive cocci, the most important organisms. These are the new recommendations.

Antibiotic treatment of bacterial endocarditis

1987 ◽  
Vol 25 (13) ◽  
pp. 49-51
Keyword(s):  
Infective Endocarditis ◽  
Antibiotic Therapy ◽  
Antibiotic Treatment ◽  
Antimicrobial Chemotherapy ◽  
Older Patients ◽  
Working Party ◽  
Bacterial Endocarditis ◽  
British Society

Infective endocarditis is at least as common today as it was 50 years ago but now affects rather older patients. Despite modern antibiotic therapy 15 to 30% of patients still die. A working party of the British Society of Antimicrobial Chemotherapy (BSAC) has recently made recommendations1 for the antibiotic treatment of streptococcal and staphylococcal endocarditis on which this article is based; advice from other specialists is also included.

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