scholarly journals Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database

2013 ◽  
Vol 31 (3) ◽  
pp. 201-206 ◽  
Author(s):  
Hirotaka Chikuda ◽  
Hideo Yasunaga ◽  
Katsushi Takeshita ◽  
Hiromasa Horiguchi ◽  
Hiroshi Kawaguchi ◽  
...  
2013 ◽  
Vol 2 (1) ◽  
pp. 81-85
Author(s):  
Abdul Qodir

Acute spinal cord injury is a devastating condition typically affecting young people, mostly males. High-Dose Methylprednisolone treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient’s life. The aim To review randomized trials of High-Dose Methylprednisolone in Acute Spinal Cord Injuries. All randomized controlled trials of steroid treatment for acute spinal cord injury in any language. Data have been extracted from original trial reports. For the NASCIS, Japanese and French trials, additional data (e.g. SDs) have been obtained from the original authors. The evidence produced by this systematic review support the use of high dose methylprednisolone in acute spinal cord injury to improve neurological recovery. Patients who received high-dose methylprednisolone therapy should be observed with intensive in order to reduce complications from such therapy.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1057
Author(s):  
Riccardo Bravi ◽  
Stefano Caputo ◽  
Sara Jayousi ◽  
Alessio Martinelli ◽  
Lorenzo Biotti ◽  
...  

Residual motion of upper limbs in individuals who experienced cervical spinal cord injury (CSCI) is vital to achieve functional independence. Several interventions were developed to restore shoulder range of motion (ROM) in CSCI patients. However, shoulder ROM assessment in clinical practice is commonly limited to use of a simple goniometer. Conventional goniometric measurements are operator-dependent and require significant time and effort. Therefore, innovative technology for supporting medical personnel in objectively and reliably measuring the efficacy of treatments for shoulder ROM in CSCI patients would be extremely desirable. This study evaluated the validity of a customized wireless wearable sensors (Inertial Measurement Units—IMUs) system for shoulder ROM assessment in CSCI patients in clinical setting. Eight CSCI patients and eight healthy controls performed four shoulder movements (forward flexion, abduction, and internal and external rotation) with dominant arm. Every movement was evaluated with a goniometer by different testers and with the IMU system at the same time. Validity was evaluated by comparing IMUs and goniometer measurements using Intraclass Correlation Coefficient (ICC) and Limits of Agreement (LOA). inter-tester reliability of IMUs and goniometer measurements was also investigated. Preliminary results provide essential information on the accuracy of the proposed wireless wearable sensors system in acquiring objective measurements of the shoulder movements in CSCI patients.


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