scholarly journals Passage of molecules through the wall of the gastrointestinal tract. II. Application of low-molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man.

Gut ◽  
1980 ◽  
Vol 21 (3) ◽  
pp. 208-214 ◽  
Author(s):  
T Sundqvist ◽  
K E Magnusson ◽  
R Sjodahl ◽  
I Stjernstrom ◽  
C Tagesson
Keyword(s):  
Mathematical Model ◽  
Molecular Weight ◽  
Gastrointestinal Tract ◽  
Intestinal Permeability ◽  
Low Molecular Weight

Intestinal Permeability to Proteins in the Newborn Herbivore

1957 ◽  
Vol 191 (2) ◽  
pp. 271-276 ◽  
Author(s):  
H. F. Deutsch ◽  
Vearl R. Smith
Keyword(s):  
Molecular Weight ◽  
Intestinal Permeability ◽  
Whey Proteins ◽  
Biological Agents ◽  
Low Molecular Weight ◽  
Milk Whey ◽  
Protein Molecules ◽  
Ready Access

The permeability of the gut of the newborn herbivore to the protein molecules of milk whey is largely lost within 24 hours following birth. All of the colostrum whey proteins, not only the antibody fraction, are absorbed during this stage of intestinal permeability. The nonantibody proteins are molecules of relatively low molecular weight. These are rapidly lost through the kidney, the antibodies being largely retained. Crystalline ß-lactoglobulin may be prepared from urine during the proteinuric stage which is very pronounced during the first 24 hours of postpartum life in calves that have had ready access to milk. Unsuccessful attempts were made to maintain the intestinal permeability beyond the first 24 hours of postpartum life. Hormonal and milk factors did not appear to be responsible for the discussed change. Transfusing with the blood of the mother and other biological agents were also ineffective.

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