PTH-046 Comparison of Outcomes of Co-Therapy Allopurinol with Low Dose Thiopurines with and Without Metabolite Profiling in Inflammatory Bowel Disease

Gut ◽  
2016 ◽  
Vol 65 (Suppl 1) ◽  
pp. A241.2-A242
Author(s):  
A Taylor Gonzalez ◽  
P Kerr ◽  
A Ansari
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Metabolite Profiling ◽  
Low Dose ◽  
Inflammatory Bowel

scholarly journals Su1862 – Low-Dose Methotrexate is Equally Effective As High-Dose in Combination with Anti-TNF Therapy in Inflammatory Bowel Disease

2019 ◽  
Vol 156 (6) ◽  
pp. S-639-S-640
Author(s):  
Nienke Z. Borren ◽  
Jay Luther ◽  
Francis Colizzo ◽  
John J. Garber ◽  
Hamed Khalili ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Low Dose ◽  
High Dose ◽  
Dose Methotrexate ◽  
Inflammatory Bowel

P-132 YI Experience with Low-Dose Mycophenolate for the Inflammatory Bowel Disease Population

2013 ◽  
Vol 19 ◽  
pp. S76-S77
Author(s):  
Benjamin Hall ◽  
Rinjal Brahmbhatt ◽  
Terrence Frick ◽  
Mark Reichelderfer ◽  
Sumona Saha
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Low Dose ◽  
Inflammatory Bowel

Low-dose thiopurine with allopurinol co-therapy overcomes thiopurine intolerance and allows thiopurine continuation in inflammatory bowel disease

2018 ◽  
Vol 50 (7) ◽  
pp. 682-688 ◽  
Author(s):  
Abhinav Vasudevan ◽  
Lauren Beswick ◽  
Antony B. Friedman ◽  
Alicia Moltzen ◽  
James Haridy ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Low Dose ◽  
Inflammatory Bowel

scholarly journals A comparative analysis of tioguanine versus low-dose thiopurines combined with allopurinol in inflammatory bowel disease patients

2020 ◽  
Vol 51 (11) ◽  
pp. 1076-1086
Author(s):  
Vince B. C. Biemans ◽  
Edo Savelkoul ◽  
Ruben Y. Gabriëls ◽  
Melek Simsek ◽  
Gerard Dijkstra ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Comparative Analysis ◽  
Bowel Disease ◽  
Low Dose ◽  
Inflammatory Bowel

scholarly journals A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood

2020 ◽  
Vol 319 (3) ◽  
pp. G361-G374 ◽  
Author(s):  
Eloisa Salvo ◽  
Patricia Stokes ◽  
Ciara E. Keogh ◽  
Ingrid Brust-Mascher ◽  
Carly Hennessey ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Early Life ◽  
Low Dose ◽  
Behavioral Deficits ◽  
Colonic Inflammation ◽  
Gut Dysbiosis ◽  
Pediatric Inflammatory Bowel Disease ◽  
Adult Mice ◽  
Inflammatory Bowel

Here we describe long-lasting impacts on the microbiota-gut-brain (MGB) axis following administration of low-dose dextran sodium sulfate (DSS) to weaning mice (P21), including gut dysbiosis, colonic inflammation, and brain/behavioral deficits in adulthood (P56). Early-life DSS leads to acute colonic inflammation, similar to adult mice; however, it results in long-lasting deficits in the MGB axis in adulthood (P56), in contrast to the transient deficits seen in adult DSS. This model highlights the unique features of pediatric inflammatory bowel disease.

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