48 Iron deficiency in heart failure: a retrospective review of current practice and patient outcomes in a district general hospital

Author(s):  
Nikhil Chatrath ◽  
Suman Kundu ◽  
Jayesh Makan
Author(s):  
Joanna Sophia J Vinke ◽  
Marith I Francke ◽  
Michele F Eisenga ◽  
Dennis A Hesselink ◽  
Martin H de Borst

Abstract Iron deficiency (ID) is highly prevalent in kidney transplant recipients (KTRs) and has been independently associated with an excess mortality risk in this population. Several causes lead to ID in KTRs, including inflammation, medication and an increased iron need after transplantation. Although many studies in other populations indicate a pivotal role for iron as a regulator of the immune system, little is known about the impact of ID on the immune system in KTRs. Moreover, clinical trials in patients with chronic kidney disease or heart failure have shown that correction of ID, with or without anaemia, improves exercise capacity and quality of life, and may improve survival. ID could therefore be a modifiable risk factor to improve graft and patient outcomes in KTRs; prospective studies are warranted to substantiate this hypothesis.


Heart ◽  
2016 ◽  
Vol 102 (Suppl 6) ◽  
pp. A12.1-A12
Author(s):  
Clare Coyle ◽  
Baltazar Nyathi ◽  
Simon Woldman ◽  
Mihir Sanghvi ◽  
Lindsey Iles ◽  
...  

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