Intratumoral blood flow in cervical cancer as assessed by transvaginal color doppler ultrasonography: Correlation with tumor characteristics

The objective of this study was to evaluate whether intratumoral blood flow as assessed by transvaginal color Doppler ultrasonography (TVCD) correlates with some tumor features in cervical cancer. Clinical, sonographic, and histologic data on 49 women (mean age: 50.3 years, range: 25–85 years) diagnosed as having a carcinoma from the uterine cervix were reviewed. Intratumoral blood flow was assessed by TVCD in all cases. Subjective impression of the amount of flow (scanty, moderate, or abundant) as well as the lowest resistance index (RI) and highest peak systolic velocity (PSV, cm/s) were used for analysis. These data were correlated with some tumoral features such as histologic type, histologic grade, tumor volume, and tumor stage. Intratumoral blood flow was found in all cases. Abundant blood flow was found more frequently in squamous carcinoma, moderately or poorly differentiated tumors, tumors with larger volume, and advanced stage tumors (P < 0.0001). Significantly lower RI was found in moderately or poorly differentiated tumors and advanced stage tumors (P < 0.01) and significantly higher PSV was found in moderately or poorly differentiated tumors, tumors with larger volume, and advanced stage tumors (P < 0.01). No correlation was found between RI and PSV and histologic type. Our data indicate that intratumoral blood flow as assessed by TVCD correlates well with some tumor features in cervical cancer.

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P21.11: Intratumoral blood flow in cervical cancer as assessed by transvaginal color Doppler ultrasonography. Corellation with tumor characteristics.

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.7306 ◽

2009 ◽

Vol 34 (S1) ◽

pp. 262-262

Author(s):

D. Diamantopoulos ◽

J. Kosmas ◽

S. Mesogitis ◽

A. Rodolakis ◽

A. Antsaklis

Keyword(s):

Cervical Cancer ◽

Blood Flow ◽

Doppler Ultrasonography ◽

Color Doppler ◽

Color Doppler Ultrasonography ◽

Tumor Characteristics

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Intratumoral blood flow in cervical cancer as assessed by transvaginal color doppler ultrasonography: Correlation with tumor characteristics

International Journal of Gynecological Cancer ◽

10.1046/j.1525-1438.2003.13302.x ◽

2003 ◽

Vol 13 (4) ◽

pp. 510-514 ◽

Cited By ~ 22

Author(s):

J. L. Alcazar ◽

G. Castillo ◽

M. Jurado ◽

G. Lopez-Garcia

Keyword(s):

Cervical Cancer ◽

Blood Flow ◽

Doppler Ultrasonography ◽

Color Doppler ◽

Color Doppler Ultrasonography ◽

Tumor Characteristics

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Vascular Waveform Analysis of Flap-Feeding Vessels Using Color Doppler Ultrasonography

Plastic Surgery International ◽

10.1155/2014/249670 ◽

2014 ◽

Vol 2014 ◽

pp. 1-8 ◽

Cited By ~ 3

Author(s):

Akihiro Ogino ◽

Kiyoshi Onishi

Keyword(s):

Blood Flow ◽

Flow Velocity ◽

Doppler Ultrasonography ◽

Color Doppler ◽

Resistance Index ◽

Color Doppler Ultrasonography ◽

Waveform Analysis ◽

Flow Volume ◽

Arterial Waveform ◽

Feeding Vessels

We performed vascular waveform analysis of flap-feeding vessels using color Doppler ultrasonography and evaluated the blood flow in the flaps prior to surgery. Vascular waveform analysis was performed in 19 patients. The analyzed parameters included the vascular diameter, flow volume, flow velocity, resistance index, pulsatility index, and acceleration time. The arterial waveform was classified into 5 types based on the partially modified blood flow waveform classification reported by Hirai et al.; in particular, D-1a, D-1b, and D-2 were considered as normal waveforms. They were 4 patients which observed abnormal vascular waveform among 19 patients (D-4 : 1, D-3 : 1, and Poor detect : 2). The case which presented D-4 waveform changed the surgical procedure, and a favorable outcome was achieved. Muscle flap of the case which presented D-3 waveform was partially necrosed. The case which detected blood flow poorly was judged to be the vascular obstruction of the internal thoracic artery. In the evaluation of blood flow in flaps using color Doppler ultrasonography, determination of not only basic blood flow information, such as the vascular distribution and diameter and flow velocity, but also the flow volume, vascular resistance, and arterial waveform is essential to elucidate the hemodynamics of the flap.

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