scholarly journals Review of Trillat, Dejour and Couette on ‘Diagnosis and treatment of recurrent dislocations of the patella’

Author(s):  
Ricardo Bastos ◽  
Daniel Wascher ◽  
Charles Fiquet ◽  
John P Fulkerson ◽  
João Espregueira-Mendes ◽  
...  

‘Numerous operations have been described for correction of recurrent dislocation of the patella. The number in itself predicates that the problem has not been solved’.This classic discusses the original publication ‘Diagnosis and treatment of recurrent dislocations of the patella’ from Trillat A, Dejour H, Couette A. Published in 1964 at the Revue de Chirurgie Orthopedique et Reparatrice de L'appareil Moteur, where the authors described a surgical procedure modifying Elmslie’s original surgery for patients with objective patellar dislocations and also for patients with anterior knee pain who had the sign of the ‘baïonnette’. Medialisation of the anterior tibial tubercle (ATT) has been known worldwide as the Elmslie-Trillat procedure, but the history of procedure has its roots going back to 1888. The history of the publications of the Elmslie-Trillat technique is really something special. César Roux published in 1888 the original technique that is similar to Elmislie’s procedure. In 1944 in London, Trillat met Selddon and became aware about Elmslie’s procedure for the ATT medialisation. Back to France, Trillat published and named it as the Elmslie’s technique. Later, after the ‘Journées du Genou’, the technique was disseminated as ‘The Elmslie-Trillat’ procedure. Nowadays, isolated ATT medialisation, the ‘true’ Elmslie-Trillat operation, is still occasionally performed. Too few surgeons use these elegant operations largely because the details of the techniques are not taught routinely. This classic section has the objective to encourage young surgeons to learn tibial tubercle transfer operations and the benefits they bring to patients when performed for proper indications.

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Angelo V. Vasiliadis ◽  
Alexandros Maris ◽  
Srinivas Gadikoppula

Tibia vara is an asymmetrical disorder of the proximal tibia that produces a three-dimensional deformity, which was first described by Blount in 1937. A 6-year-old boy presented with a history of anterior knee pain with progressive bowing of his right leg over the last 1 year after having a fall while playing soccer. An early diagnosis and treatment of this disease can have a great functional impact and lead to very good health outcomes.


1997 ◽  
Vol 25 (3) ◽  
pp. 375-381 ◽  
Author(s):  
Johan Bellemans ◽  
Frank Cauwenberghs ◽  
Eric Witvrouw ◽  
Peter Brys ◽  
Jan Victor

Author(s):  
John Mukhopadhaya ◽  
Arvind Gupta ◽  
Amit K. Sinha ◽  
Janki S. Bhadani

<p><strong>Background</strong>-Chronic patellar instability (subluxation and dislocation) and pain is a debilitating knee condition that frequently involves young, active patients. Bony malalignment and soft tissue injury (torn or stretched MPFL) is considered as a surgical indication for distal realignment in the form of Anteromedial tibial tubercle transfer(Fulkerson osteotomy) with or without MPFL reconstruction that effectively prevents the patella from tracking laterally and thus unloads the lateral patella while making the patellofemoral joint more congruous , stable and pain free.</p><p><strong>Materials and method</strong> - It is a prospective study of 22 patients of chronic patellar instability and pain. Follow up ranged from 24 to 36(average 30) months. Preoperative assessment included clinical examination, Lysholm, IKDC score and Radiological examination (X-ray, CT scan and MRI). 18 patients with history of dislocation and pain having bony malalignment and torn MPFL were treated with Fulkerson osteotomy and MPFL reconstruction and 4 patients with history of subluxation and pain having bony malalignment only were treated with Fulkerson osteotomy alone. Patients were followed up with the help of X-rays at regular interval and the clinical outcome was measured using scoring system.</p><p><strong> </strong><strong>Results</strong>-There was a significant improvement in postoperative assessment with regards to scoring system (Lysholm and IKDC) and knee pain. Union at osteotomy site for all patients was seen. None of the patients had further episode of dislocation or subluxation. Pain at femoral site of MPFL reconstruction in 2 cases persisted for 3 months followed by resolution of their symptoms. One of our patients had profuse swelling at the site of operation postoperatively which was treated with Rest, Ice Pack, Compression and Limb elevation. Out of 22 patients undertaken infection at osteotomy site was seen in 1 patient for which implant removal was done from osteotomy site after union.</p><p> <strong>Conclusion</strong>-Anteromedial Tibial tuberosity osteotomy and MPFL reconstruction is a successful procedure to treat patellofemoral pain and instability.</p>


Author(s):  
Mirazkar D. Pandareesh ◽  
Vivek Hamse Kameshwar ◽  
Kullaiah K. Byrappa

: Prostate cancer is a multifactorial disease that mainly occurs due to the accumulation of somatic, genetic and epigenetic changes, resulting in the inactivation of tumor-suppressor genes and activation of oncogenes. Mutations in genes, specifically those that control cell growth and division or the repair of damaged DNA, make the cells grow and divide uncontrollably to form a tumor. The risk of developing prostate cancer depends upon the gene that has undergone the mutation. Identifying such genetic risk factors for prostate cancer pose a challenge for the researchers. Besides genetic mutations, many epigenetic alterations including DNA methylation, histone modifications (methylation, acetylation, ubiquitylation, sumoylation, and phosphorylation) nucleosomal remodelling, and chromosomal looping, have been significantly contributed to the onset of prostate cancer as well as the prognosis, diagnosis, and treatment of prostate cancer. Chronic inflammation also plays a major role in the onset and progression of human cancer, via. modifications in the tumor microenvironment by initiating epithelial-mesenchymal transition and remodelling the extracellular matrix. In this article, the authors present a brief history of the mechanisms and potential links between the genetic aberrations, epigenetic changes, inflammation and inflammasomes that are known to contribute to the prognosis of prostate cancer. Furthermore, the authors examine and discuss clinical potential of prostate carcinogenesis in relation to epigenetics and inflammation for its diagnosis and treatment.


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