Intractable hiccup and nausea in neuromyelitis optica with anti-aquaporin-4 antibody: a herald of acute exacerbations

2008 ◽  
Vol 79 (9) ◽  
pp. 1075-1078 ◽  
Author(s):  
T Takahashi ◽  
I Miyazawa ◽  
T Misu ◽  
R Takano ◽  
I Nakashima ◽  
...  
2011 ◽  
Vol 18 (2) ◽  
pp. 244-247 ◽  
Author(s):  
Sung-Min Kim ◽  
Ji-Soo Kim ◽  
Young Eun Heo ◽  
Hye-Ran Yang ◽  
Kyung Seok Park

Neuromyelitis optica (NMO), mainly affecting optic nerve and spinal cord, can also manifest diverse ocular symptoms due to brain abnormalities. We present a cortical oscillopsia without nystagmus or head tremor in a patient with neuromyelitis optica spectrum disorder (NMOSD) with anti-aquaporin 4 antibody. This rare ocular manifestation, which is easily underestimated owing to absence of the typical nystagmus, can be an initial manifestation of NMOSD.


2012 ◽  
Vol 18 (2) ◽  
pp. 76-79 ◽  
Author(s):  
Kotaro Ogaki ◽  
Takashi Hirayama ◽  
Karina Chijiiwa ◽  
Jiro Fukae ◽  
Tsuyoshi Furuya ◽  
...  

2011 ◽  
Vol 18 (7) ◽  
pp. 997-998 ◽  
Author(s):  
Ichiro Nakashima ◽  
Toshiyuki Takahashi ◽  
Bruce A.C. Cree ◽  
Ho Jin Kim ◽  
Chihiro Suzuki ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
pp. 40-44
Author(s):  
Enrique Gomez‐Figueroa ◽  
Christian Garcia‐Estrada ◽  
Adriana Casallas-Vanegas ◽  
Indhira Zabala-Angeles ◽  
Ramon Lopez-Martinez ◽  
...  

2017 ◽  
Vol 309 ◽  
pp. 38-40 ◽  
Author(s):  
Tomoya Kon ◽  
Tatsuya Ueno ◽  
Chieko Suzuki ◽  
Jinichi Nunomura ◽  
Shohei Igarashi ◽  
...  

2018 ◽  
Vol 103 (6) ◽  
pp. 789-796 ◽  
Author(s):  
Yongheng Huang ◽  
Lei Zhou ◽  
Jingzi ZhangBao ◽  
Tongjia Cai ◽  
Bei Wang ◽  
...  

Background/aimsCurrent understanding of the alterations in the retinal vascular network in neuromyelitis optica spectrum disorders (NMOSDs) is limited. We aim to assess the peripapillary and parafoveal vessel density in aquaporin-4 antibody-positive NMOSD patients by optical coherence tomography (OCT) angiography.MethodsA total of 55 aquaporin-4 antibody-positive NMOSD patients with or without a history of optic neuritis (ON) and 33 healthy controls underwent spectral domain OCT and OCT angiography. Clinical histories, Expanded Disability Status Scale score, visual functional system score (VFSS) and disease duration were collected.ResultsPeripapillary and parafoveal vessel density was significantly decreased in NMOSD eyes with or without a history of ON. The decrease in retinal vessel density could occur before ON and retinal nerve fibre layer (RNFL) atrophy. Peripapillary vessel density correlated well with the spectral domain OCT measurements and VFSS in NMOSD eyes with a history of ON.ConclusionSubclinical primary retinal vasculopathy may occur in NMOSD prior to ON and RNFL atrophy. Peripapillary vessel density might be a sensitive predictor of visual outcomes in NMOSD patients with ON.


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