scholarly journals P236 Is annual cervical cytology in HIV positive women justified in the era of HPV testing? a 2-year study in a district general hospital:

2015 ◽  
Vol 91 (Suppl 1) ◽  
pp. A93.3-A94
Author(s):  
Nisha Pal ◽  
Mamatha Odhuru ◽  
Noreen Desmond
Keyword(s):  
General Hospital ◽  
District General Hospital ◽  
Cervical Cytology ◽  
Hiv Positive ◽  
Hpv Testing ◽  
Hiv Positive Women

scholarly journals Prevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive women

2019 ◽  
Vol 8 (9) ◽  
pp. 3649
Author(s):  
Sunita Malik ◽  
Supriti Kumari ◽  
Harsha S. Gaikwad ◽  
Archana Mishra ◽  
Mausumi Bharadwaj
Keyword(s):  
Hpv Infection ◽  
Cervical Cytology ◽  
Hiv Positive ◽  
Abnormal Cytology ◽  
Cross Sectional ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Abnormal Cervical Cytology ◽  
Hiv Positive Women ◽  
Relationship Of

Background: The relationship among HIV, HPV, and development of CIN is complex and incompletely understood. Present study is undertaken to find out the prevalence and relationship of abnormal cervical cytology and HPV infection in HIV positive women.Methods: This was a cross-sectional, case control study conducted on 95 HIV seropositive and 95 seronegative women. Specimen was collected from the cervix for HPV DNA testing, subtyping and cytology.Results: HPV DNA positivity was higher in seropositive group (18.6% vs. 7.4%). Premalignant conditions were found only in seropositive group. At CD4 count <249 HPV DNA positivity was 53%, at 250-499 the percentage of HPV DNA positivity was 31% and at >500 HPV DNA positivity was 19%.Conclusions: Prevalence of abnormal cytology and HPV DNA positivity is higher amongst HIV positive women and there is an association between HPV DNA positivity with lower CD4 counts. 

Human Papillomavirus Co-Testing Results Effectively Triage Normal Cervical Cytology in HIV-Positive Women Aged 30 Years and Older

2017 ◽  
Vol 21 (2) ◽  
pp. 125-128 ◽  
Author(s):  
Rachel O. Alade ◽  
Olivera Vragovic ◽  
Conor Duffy ◽  
Howard J. Cabral ◽  
Elizabeth A. Stier
Keyword(s):  
Human Papillomavirus ◽  
Cervical Cytology ◽  
Hiv Positive ◽  
Hiv Positive Women ◽  
Normal Cervical Cytology

scholarly journals Abnormal cervical cytology amongst women infected with human immunodeficiency virus in Limpopo province, South Africa

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Samuel T. Ntuli ◽  
Eric Maimela ◽  
Linda Skaal ◽  
Mabina Mogale ◽  
Provia Lekota
Keyword(s):  
South Africa ◽  
Cervical Cancer ◽  
Human Immunodeficiency Virus ◽  
Limpopo Province ◽  
Cervical Cytology ◽  
Hiv Positive ◽  
Abnormal Cytology ◽  
Abnormal Cervical Cytology ◽  
Hiv Positive Women ◽  
Immunodeficiency Virus

Background: Cervical cancer remains the major public problem worldwide and the most common gynaecological malignancy in the developing world, particularly in sub-Saharan Africa.Aim: To determine the prevalence of abnormal cervical cytology amongst women with and without human immunodeficiency virus (HIV) and examine the association between HIV and histological grading.Setting: The study was conducted in Limpopo province, which is the northernmost province of South Africa. The province has five district municipalities with one tertiary, five regional and thirty four district hospitals.Methods: We retrospectively reviewed cervical cancer cases in Limpopo province (LP) of South Africa, using data collected routinely by the National Health Laboratory Services (NHLS). The data on smears submitted for cytology between 2013 and 2015 were extracted from the Central Data Warehouse (CDW) database.Results: A total of 84 466 women were screened for cervical cytology smears. Their mean age was 39.8 ± 13.6 years, with range from 15 to 113 years; 77.2% were in the age group 30 years and older and 19.6% had an abnormal cervical cytology result. Overall, 46.4% of the women screened for cervical cancer were HIV infected. A significantly higher proportion of HIV-positive women had abnormal cytology than HIV-negative women (31.8% vs. 9.2%).Conclusion: The prevalence of abnormal cytology amongst HIV-positive women is relatively high, and the risk appears to be significantly greater in all age groups. This finding highlights the need to ascertain HIV status of all women presenting with cervical cancer.

Abnormal cervical cytology among HIV-positive women in Nigeria

2014 ◽  
Vol 125 (2) ◽  
pp. 103-106 ◽  
Author(s):  
Goddy Bassey ◽  
Israel Jeremiah ◽  
John I. Ikimalo ◽  
Preye O. Fiebai ◽  
Boma P. Athanasius
Keyword(s):  
Cervical Cytology ◽  
Hiv Positive ◽  
Abnormal Cervical Cytology ◽  
Hiv Positive Women

scholarly journals Performance of vaginal self-sampling for human papillomavirus testing among women living with HIV in Botswana

2019 ◽  
Vol 30 (12) ◽  
pp. 1169-1176 ◽  
Author(s):  
Tamara Elliott ◽  
Racquel E Kohler ◽  
Barati Monare ◽  
Neo Moshashane ◽  
Kehumile Ramontshonyana ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Hiv Positive ◽  
Hpv Testing ◽  
High Coverage ◽  
Screening Programs ◽  
Women Living With Hiv ◽  
Hiv Positive Women ◽  
Immunodeficiency Virus ◽  
High Cervical ◽  
Living With Hiv

In Botswana, where human immunodeficiency virus (HIV) prevalence remains high, cervical cancer is the leading cause of cancer deaths in women. Multiple organizations recommend high-risk human papillomavirus (hr-HPV) testing as a screening tool; however, high coverage may not be feasible with provider-collected samples. We conducted the first assessment of self- versus provider-collected samples for hr-HPV testing in HIV-positive women in Botswana and report prevalence of hr-HPV and histological outcomes. We recruited HIV-positive women ≥25 years attending an HIV clinic in Gaborone. Self- and provider-collected samples from participants were tested for hr-HPV using Cepheid GeneXpert. Women testing positive for any hr-HPV returned for colposcopy. We used unweighted κ statistics to determine hr-HPV agreement. We report that 31 (30%) of 103 women tested positive for any hr-HPV. The most common genotypes were HPV 31/33/35/52/58. Overall agreement between self- and provider-collected samples for any hr-HPV was 92% with a κ of 0.80. Ten of the 30 hr-HPV-positive women attending colposcopy had CIN2+ (33%). In conclusion, in this HIV-positive population, there was excellent agreement between self and provider samples, and self-sampling may play an important role in screening programs in high HIV burden settings with limited resources like Botswana.

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