scholarly journals Bilateral empyema and purulent pericarditis due to Haemophilus influenzae capsular type b.

Thorax ◽  
1988 ◽  
Vol 43 (7) ◽  
pp. 582-583 ◽  
Author(s):  
R Iggo ◽  
R Higgins
1988 ◽  
Vol 100 (2) ◽  
pp. 193-203 ◽  
Author(s):  
A. J. Howard ◽  
K. T. Dunkin ◽  
G. W. Millar

SUMMARYAn investigation was undertaken to determine the isolation rate and antibiotic resistance ofHaemophilus influenzaefrom the nasopharynx of young children. The 996 subjects studied were up to 6 years of age.H. influenzaewas isolated from 304 (30·5%) and strains of capsular type b from 11 (1·1%). Age, sibling status, season, respiratory infection and antibiotic therapy all influenced isolation rates. The overall prevalence of antibiotic resistance in the strains isolated was ampicillin 5·4% (all β-lactamase producers), cefaclor 0·3%, chloramphenicol 1·3%, erythromycin 38·2%, tetracycline 1·3%, trimethoprim 5·4% and sulphamethoxazole 0%. Ampicillin resistance was more common in type b than non-capsulated strains.


1981 ◽  
Vol 3 (4) ◽  
pp. 105-130

Haemophilus influenzae type b can cause pneumonia. Although the frequency has not been accurately assessed, this etiology is not rare and may represent as much as one third of hospitalized patients with bacterial pneumonia. Approximately half have pleural involvement. The majority of patients have associated manifestations including otitis, meningitis, purulent pericarditis and epiglottitis. Cultures from the blood and localized areas (pleural fluid, etc) are usually positive and establish the diagnosis. Countercurrent immunoelectrophoresis (CIE) may be helpful in the partially treated child. Comment: H influenzae b can cause a variety of diseases including, obviously more commonly than heretofore believed, pneumonia. Treatment of this illness depends upon the B lactamase production by the isolated Haemophilus.


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