MELANIN PIGMENTATION IN BOVINE PINEAL GLAND AND ITS POSSIBLE CORRELATION WITH GONADAL FUNCTION

1958 ◽  
Vol 36 (2) ◽  
pp. 227-235 ◽  
Author(s):  
Enrique Santamarina
Keyword(s):  
Pineal Gland ◽  
Strong Evidence ◽  
Spectrophotometric Analysis ◽  
Black Pigment ◽  
Gonadal Function ◽  
Melanin Pigmentation ◽  
Degenerative Process ◽  
Aging Phenomenon ◽  
Bovine Pineal Gland

The incidence of melanin in the bovine pineal gland was studied in 880 glands. Spectrophotometric analysis and chemical and cytochemical methods identified the black pigment present in the bovine pineal gland as melanin. No melanin was found in bulls 4 and 5 years of age nor in heifers of about 18 months. In pregnant cows over 5 years of age melanin was found in 5.4% of the pineal glands. Non-pregnant cows of the same age exhibited melanin in 8.5% of the pineal glands. Castrated male cattle between 18 and 24 months of age showed 49.6% of the pineal glands with macroscopical signs of melanization. As much as 67% of the pineal glands of steers from some herds contained melanin. In intact cattle melanin in the pineal appears to be mainly an aging phenomenon. The fact that castration in male cattle causes hypertrophy of the pineal gland followed by a degenerative process in which melanin is involved seems to give strong evidence of a pineal gonadal interrelationship. The possible role of the hormones in the phenomenon of melanin formation is discussed.

MELANIN PIGMENTATION IN BOVINE PINEAL GLAND AND ITS POSSIBLE CORRELATION WITH GONADAL FUNCTION

1958 ◽  
Vol 36 (1) ◽  
pp. 227-235 ◽  
Author(s):  
Enrique Santamarina
Keyword(s):  
Pineal Gland ◽  
Strong Evidence ◽  
Spectrophotometric Analysis ◽  
Black Pigment ◽  
Gonadal Function ◽  
Melanin Pigmentation ◽  
Degenerative Process ◽  
Aging Phenomenon ◽  
Bovine Pineal Gland

The incidence of melanin in the bovine pineal gland was studied in 880 glands. Spectrophotometric analysis and chemical and cytochemical methods identified the black pigment present in the bovine pineal gland as melanin. No melanin was found in bulls 4 and 5 years of age nor in heifers of about 18 months. In pregnant cows over 5 years of age melanin was found in 5.4% of the pineal glands. Non-pregnant cows of the same age exhibited melanin in 8.5% of the pineal glands. Castrated male cattle between 18 and 24 months of age showed 49.6% of the pineal glands with macroscopical signs of melanization. As much as 67% of the pineal glands of steers from some herds contained melanin. In intact cattle melanin in the pineal appears to be mainly an aging phenomenon. The fact that castration in male cattle causes hypertrophy of the pineal gland followed by a degenerative process in which melanin is involved seems to give strong evidence of a pineal gonadal interrelationship. The possible role of the hormones in the phenomenon of melanin formation is discussed.

Concurrent Electrodermal and Eyeblink Conditioning With Masked and Unmasked Stimuli

2021 ◽  
Vol 35 (1) ◽  
pp. 35-42
Author(s):  
José Luis Marcos ◽  
Azahara Marcos
Keyword(s):  
Unconditioned Stimulus ◽  
Strong Evidence ◽  
Eyeblink Conditioning ◽  
Noise Burst ◽  
Conditioning Phase ◽  
Contingency Awareness ◽  
Blank Screen ◽  
Neutral Face ◽  
Fearful Face

Abstract. The aim of this study was to determine if contingency awareness between the conditioned (CS) and unconditioned stimulus (US) is necessary for concurrent electrodermal and eyeblink conditioning to masked stimuli. An angry woman’s face (CS+) and a fearful face (CS−) were presented for 23 milliseconds (ms) and followed by a neutral face as a mask. A 98 dB noise burst (US) was administered 477 ms after CS+ offset to elicit both electrodermal and eyeblink responses. For the unmasking conditioning a 176 ms blank screen was inserted between the CS and the mask. Contingency awareness was assessed using trial-by-trial ratings of US-expectancy in a post-conditioning phase. The results showed acquisition of differential electrodermal and eyeblink conditioning in aware, but not in unaware participants. Acquisition of differential eyeblink conditioning required more trials than electrodermal conditioning. These results provided strong evidence of the causal role of contingency awareness on differential eyeblink and electrodermal conditioning.

BLOCKADE OF THE SURGE OF PROLACTIN AT PRO-OESTRUS BY ADMINISTRATION OF ANTI-OESTROGENIC SUBSTANCE, MER-25

1973 ◽  
Vol 74 (4) ◽  
pp. 769-774 ◽  
Author(s):  
Akira Yokoyama ◽  
Hiroshi Tomogane ◽  
Katuaki Ôta
Keyword(s):  
Strong Evidence ◽  
The Other ◽  
Other Hand

ABSTRACT A non-steroidal oestrogen antagonist, MER-25, was administered to cycling rats for elucidating the role of oestrogen in the surge of prolactin observed on the afternoon of pro-oestrus (POe). In animals injected with 20 mg of MER-25 intramuscularly on the afternoon (16.30 h) of the first day of dioestrus (D-1), the surge of prolactin was blocked while the level of prolactin on the afternoon of POe of these animals was significantly higher than that of the corresponding controls injected with oil. Ovulation was also blocked in these animals treated with the drug on the afternoon of D-l. On the other hand, treatment on the morning (10.30 h) of the 2nd day of dioestrus failed to prevent not only the surge of prolactin but also ovulation. These observations provide strong evidence for the view that oestrogen is responsible for the surge of prolactin on the afternoon of POe, and that the surge is accompanied by that of LH.

scholarly journals Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland

2019 ◽  
Vol 68 (2) ◽  
Author(s):  
Mikkel B. Carstensen ◽  
Henrik Hertz ◽  
Tenna Bering ◽  
Morten Møller ◽  
Kristian Rohde ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Homeobox Gene ◽  
Circadian Regulation

Seasonal changes of SP and NKA in frontal cortex, striatum and testes in the rat. Role of maternal pineal gland

Peptides ◽  
2004 ◽  
Vol 25 (6) ◽  
pp. 997-1004 ◽  
Author(s):  
N Vázquez Moreno ◽  
L Debeljuk ◽  
E Dı́az Rodrı́guez ◽  
C Fernández Alvarez ◽  
B Dı́az López
Keyword(s):  
Pineal Gland ◽  
Frontal Cortex ◽  
Seasonal Changes

Characterization of a Cytosol Progesterone Receptor in Bovine Pineal Gland

1979 ◽  
Vol 29 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Maria I. Vacas ◽  
Pedro R. Lowenstein ◽  
Daniel P. Cardinali
Keyword(s):  
Progesterone Receptor ◽  
Pineal Gland ◽  
Bovine Pineal Gland

scholarly journals Some Regions within Broca's Area Do Respond More Strongly to Sentences than to Linguistically Degraded Stimuli: A Comment on Rogalsky and Hickok ()

2011 ◽  
Vol 23 (10) ◽  
pp. 2632-2635 ◽  
Author(s):  
Evelina Fedorenko ◽  
Nancy Kanwisher
Keyword(s):  
Random Effects ◽  
Language Processing ◽  
Cognitive Neuroscience ◽  
Strong Evidence ◽  
Sentence Comprehension ◽  
Broca’S Area ◽  
Broca's Area ◽  
Review Of The Literature

On the basis of their review of the literature, Rogalsky and Hickok [Rogalsky, C., & Hickok, G. The role of Broca's area in sentence comprehension. Journal of Cognitive Neuroscience, 23, 1664–1680, 2011] conclude that there is currently no strong evidence for the existence of “sentence-specific processing regions within Broca's area” (p. 1664). Their argument is based, in part, on the observation that many previous studies have failed to detect an effect in the left inferior frontal regions for contrasts between sentences and linguistically degraded control conditions (e.g., lists of unconnected words, lists of nonwords, or acoustically degraded sentence stimuli). Our data largely replicate this lack of activation in inferior frontal regions when traditional random-effects group analyses are conducted but crucially show robust activations in the same data for the same contrasts in almost every subject individually. Thus, it is the use of group analyses in studies of language processing, not the idea that sentences robustly activate frontal regions, that needs to be reconsidered. This reconsideration has important methodological and theoretical implications.

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