BLOCKADE OF THE SURGE OF PROLACTIN AT PRO-OESTRUS BY ADMINISTRATION OF ANTI-OESTROGENIC SUBSTANCE, MER-25

1973 ◽  
Vol 74 (4) ◽  
pp. 769-774 ◽  
Author(s):  
Akira Yokoyama ◽  
Hiroshi Tomogane ◽  
Katuaki Ôta
Keyword(s):  

ABSTRACT A non-steroidal oestrogen antagonist, MER-25, was administered to cycling rats for elucidating the role of oestrogen in the surge of prolactin observed on the afternoon of pro-oestrus (POe). In animals injected with 20 mg of MER-25 intramuscularly on the afternoon (16.30 h) of the first day of dioestrus (D-1), the surge of prolactin was blocked while the level of prolactin on the afternoon of POe of these animals was significantly higher than that of the corresponding controls injected with oil. Ovulation was also blocked in these animals treated with the drug on the afternoon of D-l. On the other hand, treatment on the morning (10.30 h) of the 2nd day of dioestrus failed to prevent not only the surge of prolactin but also ovulation. These observations provide strong evidence for the view that oestrogen is responsible for the surge of prolactin on the afternoon of POe, and that the surge is accompanied by that of LH.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 171-174
Author(s):  
Tarare Toshida ◽  
Chaple Jagruti

The covid-19 resulted in broad range of spread throughout the world in which India has also became a prey of it and in this situation the means of media is extensively inϑluencing the mentality of the people. Media always played a role of loop between society and sources of information. In this epidemic also media is playing a vital role in shaping the reaction in ϑirst place for both good and ill by providing important facts regarding symptoms of Corona virus, preventive measures against the virus and also how to deal with any suspect of disease to overcome covid-19. On the other hand, there are endless people who spread endless rumours overs social media and are adversely affecting life of people but we always count on media because they provide us with valuable answers to our questions, facts and everything in need. Media always remains on top of the line when it comes to stop the out spread of rumours which are surely dangerous kind of information for society. So on our side we should react fairly and maturely to handle the situation to keep it in the favour of humanity and help government not only to ϑight this pandemic but also the info emic.


1992 ◽  
Vol 5 (1) ◽  
pp. 53-67
Author(s):  
D.S. Nava

The EEC Treaty contains no specific provisions for the control of concentrations. Only the competition rules. Articles 85 and 86 EEC, could be considered as possible legal instruments for regulating concentrations. The Commission has had to examine whether and to what extent these provisions could be used to this end.The Commission's view has been that Article 85 does not apply to operations resulting in structural change, as is the case of concentrations and concentrative joint ventures. Cooperative operations, such as cooperative joint ventures, on the other hand fall to be assessed under Article 85. The Philip Morris case has made this position uncertain. According to the extensive interpretation of this judgement Article 85 is now applicable to certain concentrations and thus to concentrative joint ventures.There is no such uncertainty regarding the role of Article 86 in controlling concentrative joint ventures, for the Court has established in the Continental Can case that concentrations can be caught by Article 86.With the adoption in 1989 of the Regulation on concentration control the Commission finally has a legal instrument specifically designed to regulate concentrations. However, only concentrations and concentrative joint ventures which comply with certain turnover thresholds (the so-called concentrations or concentrative joint ventures with a Community dimension) can be assessed by the Commission under the Regulation. This means that the provisions of the Regulation can not be applied to concentrative joint ventures beneath the threshold.Because of the difficulty in distinguishing concentrative operations from cooperative ones, the Commission published the Notice regarding the concentrative and cooperative operations under the Regulation on the control of concentrations.


2014 ◽  
Vol 108 (2) ◽  
pp. iii-ix

We introduce this issue with a thought. There has been much made of the need for our discipline to be “policy relevant,” and much ridicule has been directed at the Review recently that comments how little the Review offers that is relevant for decision makers. But what does it mean to be policy relevant? Generally, scholarly journals publish the best in basic research, which hopefully can be used by those in positions of authority to good effect. This often means that there are no catchy titles, nor opinion-editorial pieces that are so often portrayed as the model of policy relevant work. In our view, the role of the Review is to expand knowledge on important scholarly questions, not only to publish work that is currently popular or somehow ordained as useful by pundits. There is certainly a place for such work, but not in the pages of the Review. On the other hand, we as the editors of the Review understand the need to make the Review accessible to as broad an audience as possible, and we have made great efforts to do just that.


2009 ◽  
Vol 37 (6) ◽  
pp. 805-810
Author(s):  
Baoshan Zhang ◽  
Jun-Yan Zhao ◽  
Guoliang Yu

An examination was carried out of the influences of concealing academic achievement on self-esteem in an academically relevant social interaction based on the assumption that concealing socially devalued characteristics should influence individuals' self-esteem during social interactions. An interview paradigm called for school-aged adolescents who either were or were not low (academic) achievers to play the role of students who were or were not low achievers while answering academically relevant questions. The data suggest that the performance self-esteem of low achievers who played the role of good students was more positive than that of low achievers who played the role of low achievers. On the other hand, participants who played the role of good students had more positive performance self-esteem than did participants who played the role of low achievers.


Author(s):  
Sukini Sukini ◽  
Hilma Pami Putri

This research was designed to find out and analyze of the collaborative learning application in reading material at ninth grade of SMPN 7 Kinali Pasaman Barat. This research conducted due to several problems found in the field which were students make a fuss when working in groups, students do not listen to given the assignment by the teacher. It can be seen that there were students who work on group assignments that care and others were just busy talking with others. This research was done in order to answer the research question “What were the role of student and what were the role of teacher in collaborative learning at the ninth grade of SMPN 7 Kinali Pasaman Barat?” This research was a qualitative research using collaborative learning strategy. The purpose of this research was to find out and analyze the collaborative learning applicationin reading material at the ninth grade of SMPN 7 KinaliPasaman Barat by analyzing the teacher’s and students’ role in the collaborative learning. The researcher used interview and observation as the instrument of the research. The interview was directed to both students and teacher, which for the students contained 12 questions and for the teacher contained 7 questions. The researcher took 2 classes namely IX1 and IX2 as the observation object.                    Based on the finding from interview and observation of the collaborative learning in SMPN 7 Kinali Pasaman Barat, it was found that the teacher already fulfilled her role in the collaborative learning effectively, in the other hand the students still lack of the role as the cheer leader. They still laughed at their friends mistake. Besides that, the other roles that the students supposed to have were already done effectively. As the conclusion, the collaborative learning in SMPN 7 Kinali Pasaman Barat was good since the students and the teacher were doing their role effectively


2021 ◽  
Author(s):  
Afarin Rajaei ◽  
Saeideh Heshmati

The present study draws attention to the significance of considering mindfulness and spiritual well-being on cancer-related distress among couples with cancer during the pandemic. Dyadic data was analyzed among couples with cancer (80 couples; N=160) to examine the within-person (actor effects) and between-partner (partner effects) associations among links between mindfulness, spiritual well-being, and cancer-related distress through the use of the actor-partner interdependence model (APIM; Kashy & Kenny, 2000). Significant actor and/or partner effects were found for mindfulness and spiritual well-being in couples with cancer, a factor that predicted cancer-related distress. Spirituality seemed to only play an important role in patients’ own cancer-related distress (actor effect), with patients’ higher levels of spiritual well-being predicting patients’ lower levels of distress. On the other hand, mindfulness was not only significantly related to the cancer patient and partner’s own distress (actor effect), partner’s mindfulness was also significantly associated with the patient’s distress (partner effect). The findings underscore the need to adopt a systemic perspective that accounts for multiple, simultaneous adaptive processes including mindfulness and spiritual well-being as influences on cancer-related distress in the time of COVID-19.


Author(s):  
James Brassett

The chapter engages the outpouring of Brexit comedy as an important case study of the politics of humor. On one hand, the literature on comedy and politics has identified the subversive potential of jokes as a form of everyday resistance. On the other hand, sociological approaches have emphasized the role of stereotype and humiliation in jokes as part of a disciplinary function of humor. Building on these insights, the chapter reads prominent debates within comedy about Brexit as a vernacular form of politics. Jokes and satire perform and reperform discourses of identity. The chapter argues we should rephrase “Brexit comedy” or “the comedy of Brexit” as a socially consequential practice that teases at the (changing) social and political consensus.


2020 ◽  
Vol 31 (1) ◽  
pp. 98-107
Author(s):  
Srdjan Maras

This paper emphasizes the place and the role of the aesthetic quality and the role of the erotic in Levinas?s project that deals with ethical an-archaeology. Despite Levinas?s categorical statements that there are irreconcilable differences between ethics and aesthetics, i.e. between ethics and the erotic, above all, it is emphasized here that these differences do not represent a stark or sharp contrast, but quite contrary, they often constitute a subversive ontological element. On the other hand, somewhat unexpectedly, with its ethical anti-aestheticism Levinas?s ?noncontemporary? thought appears to be, at the same time, both significant and critical, elementary, emancipatory and contemporary in relation to present-day reactionary reactualization and revitalization of the aesthetic quality which mechanically proceeds to develop on the margins of Levinas?s emancipatory past.


Author(s):  
Vadim Markovich Rozin

The article covers the two main topics: the characteristics of three key stages of studying art by the author, and a brief summary of the original concept of art proposed as a result of this study. Leaning on the concept of art of L. S. Vygotsky, the author offers the own approach towards studying art. Firstly, art is viewed in comparison with dreams, communication and play, analyzing the role of these processes and semiotic means played in relation to ordinary life. The article introduces the idea of artistic reality, which manifests as a continuation of ordinary life, allowing to realize in a semiotic form the desires (psychic programs) that are blocked in ordinary life; and such realization suggest living through the events set by the specific semiosis of art and conditionality. Secondly, the author describes the results of the genesis of art. In the course of analysis, emphasis is place on the three central topics:: 1) establishment of the semiosis of art based on the semiosis formed in ordinary life; 2) formation of recreation sphere, within which art is being formed; 3) philosophical “conceptualization” of art in the antique culture, which characterizes art as an independent sphere of life, unlike other spheres. Thirdly, art and artistic reality are viewed as a peculiar type of communication. The author believes that both, the artist (writer, composer) and the viewer (reader, listener), on the one hand, create and reconstruct artistic reality (and there is not always a coincidence), while on the other hand, to one or another extent, they take into account each other's communicative abilities and competencies. The conclusion is made that art is determined by conceptual space, the coordinates of which indicate the representations of artistic reality, artistic communication, life patterns in art, conceptualization of art and its development.


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