scholarly journals A Review of Integration Strategies to Support Gene Regulatory Network Construction

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Hailin Chen ◽  
Vincent VanBuren
Keyword(s):  
Gene Regulatory Network ◽  
Regulatory Network ◽  
Data Sources ◽  
Second Phase ◽  
Network Construction ◽  
Structural Integration ◽  
Analytic Integration ◽  
Gene Regulatory ◽  
Two Phases ◽  
Integration Strategies

Gene regulatory network (GRN) construction is a central task of systems biology. Integration of different data sources to infer and construct GRNs is an important consideration for the success of this effort. In this paper, we will discuss distinctive strategies of data integration for GRN construction. Basically, the process of integration of different data sources is divided into two phases: the first phase is collection of the required data and the second phase is data processing with advanced algorithms to infer the GRNs. In this paper these two phases are called “structural integration” and “analytic integration,” respectively. Compared with the nonintegration strategies, the integration strategies perform quite well and have better agreement with the experimental evidence.

scholarly journals Experimental approaches for gene regulatory network construction: The chick as a model system

genesis ◽  
2012 ◽  
Vol 51 (5) ◽  
pp. 296-310 ◽  
Author(s):  
Andrea Streit ◽  
Monica Tambalo ◽  
Jingchen Chen ◽  
Timothy Grocott ◽  
Maryam Anwar ◽  
...  
Keyword(s):  
Gene Regulatory Network ◽  
Regulatory Network ◽  
Model System ◽  
Network Construction ◽  
Experimental Approaches ◽  
Gene Regulatory

A review on the computational approaches for gene regulatory network construction

2014 ◽  
Vol 48 ◽  
pp. 55-65 ◽  
Author(s):  
Lian En Chai ◽  
Swee Kuan Loh ◽  
Swee Thing Low ◽  
Mohd Saberi Mohamad ◽  
Safaai Deris ◽  
...  
Keyword(s):  
Gene Regulatory Network ◽  
Regulatory Network ◽  
Network Construction ◽  
Computational Approaches ◽  
Gene Regulatory

scholarly journals Efficient Reverse-Engineering of a Developmental Gene Regulatory Network

2012 ◽  
Vol 8 (7) ◽  
pp. e1002589 ◽  
Author(s):  
Anton Crombach ◽  
Karl R. Wotton ◽  
Damjan Cicin-Sain ◽  
Maksat Ashyraliyev ◽  
Johannes Jaeger
Keyword(s):  
Reverse Engineering ◽  
Gene Regulatory Network ◽  
Regulatory Network ◽  
Developmental Gene ◽  
Gene Regulatory
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