Mesoscopic Models of Liquid/Solid Phase Transitions

1998 ◽  
Vol 09 (08) ◽  
pp. 1405-1415 ◽  
Author(s):  
G. de Fabritiis ◽  
A. Mancini ◽  
D. Mansutti ◽  
S. Succi
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Mushy Zone ◽  
Lattice Boltzmann ◽  
Solid Phase ◽  
Chaotic Motions ◽  
Computational Costs ◽  
Mesoscopic Models ◽  
Lattice Boltzmann Models ◽  
Solid Liquid

A generalization of mesoscopic Lattice-Boltzmann models aimed at describing flows with solid/liquid phase transitions is presented. It exhibits lower computational costs with respect to the numerical schemes resulting from differential models. Moreover it is suitable to describe chaotic motions in the mushy zone.

scholarly journals Prion-Like Proteins in Phase Separation and Their Link to Disease

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1014
Author(s):  
Macy L. Sprunger ◽  
Meredith E. Jackrel
Keyword(s):  
Protein Folding ◽  
Phase Transitions ◽  
Phase Separation ◽  
Liquid Phase ◽  
Protein Misfolding ◽  
Solid Phase ◽  
Liquid Phase Separation ◽  
Therapeutic Approaches ◽  
Important Physiological Process ◽  
Liquid Liquid Phase Separation

Aberrant protein folding underpins many neurodegenerative diseases as well as certain myopathies and cancers. Protein misfolding can be driven by the presence of distinctive prion and prion-like regions within certain proteins. These prion and prion-like regions have also been found to drive liquid-liquid phase separation. Liquid-liquid phase separation is thought to be an important physiological process, but one that is prone to malfunction. Thus, aberrant liquid-to-solid phase transitions may drive protein aggregation and fibrillization, which could give rise to pathological inclusions. Here, we review prions and prion-like proteins, their roles in phase separation and disease, as well as potential therapeutic approaches to counter aberrant phase transitions.

From the bulk to clusters: Solid-liquid phase transitions and precursor effects

1990 ◽  
Vol 24-26 (1) ◽  
pp. 283-342 ◽  
Author(s):  
R. Kofman ◽  
P. Cheyssac ◽  
R. Garrigos
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Precursor Effects ◽  
Solid Liquid
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