A collaborative optimized genetic algorithm based on regulation mechanism of neuroendocrine-immune system

The immune genetic algorithm is a kind of heuristic algorithm which simulates the biological immune system and introduces the genetic operator to its immune operator. Conquering the inherent defects of genetic algorithm that the convergence direction can not be easily controlled so as to result in the prematureness；it is characterized by a better global search and memory ability. The basic principles and solving steps of the immune genetic algorithm are briefly introduced in this paper. The immune genetic algorithm is applied to the survey data processing and experimental results show that this method can be practicably and effectively applied to the survey data processing.

Download Full-text

A Path-Oriented Test Data Generation Approach Hybridizing Genetic Algorithm and Artificial Immune System

Advances in Intelligent Systems and Computing - Computational Intelligence in Data Mining ◽

10.1007/978-981-10-8055-5_58 ◽

2018 ◽

pp. 649-658

Author(s):

Gargi Bhattacharjee ◽

Ashish Singh Saluja

Keyword(s):

Genetic Algorithm ◽

Immune System ◽

Test Data ◽

Artificial Immune System ◽

Test Data Generation ◽

Data Generation ◽

Artificial Immune

Download Full-text

A method of multiobjective optimization using a genetic algorithm and an artificial immune system

Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science ◽

10.1243/09544062jmes1313 ◽

2009 ◽

Vol 223 (5) ◽

pp. 1243-1252 ◽

Cited By ~ 3

Author(s):

H Park ◽

N-S Kwak ◽

J Lee

Keyword(s):

Genetic Algorithm ◽

Pattern Recognition ◽

Immune System ◽

Artificial Immune System ◽

Affinity Maturation ◽

Pareto Optimal ◽

Mathematical Function ◽

Pareto Optimal Solutions ◽

Optimal Solutions ◽

Artificial Immune

The immune system has pattern recognition capabilities based on reinforced learning, memory, and affinity maturation interacting between antigens (Ags) and antibodies (Abs). This article deals with an adaptation of artificial immune system (AIS) into genetic-algorithm (GA)-based multi-objective optimization. The present study utilizes the pattern recognition from an AIS and the evolution from a GA. Using affinity measures between Ags and Abs, GA-based immune simulation discovers a generalist Ab that represents the common pattern among Ags. Non-dominated Pareto-optimal solutions are obtained via GA-based immune simulation in which dominated designs are considered as Ags, whereas non-dominated designs are assigned to Abs. This article discusses the procedure of identifying Pareto-optimal solutions through the immune system-based pattern recognition. A number of mathematical function problems that are described by discontinuity or disconnection in the shape of Pareto surface are first examined as test examples. Subsequently, engineering optimization problems such as rotating flywheel disc and ten-bar planar truss are explored to support the present study.

Download Full-text

Improved protein structural class prediction using genetic algorithm and artificial immune system

2009 World Congress on Nature & Biologically Inspired Computing (NaBIC) ◽

10.1109/nabic.2009.5393488 ◽

2009 ◽

Cited By ~ 1

Author(s):

Sitanshu Sekhar Sahu ◽

Ganapati Panda ◽

Satyasai Jagannath Nanda

Keyword(s):

Genetic Algorithm ◽

Immune System ◽

Artificial Immune System ◽

Artificial Immune ◽

Class Prediction ◽

Structural Class ◽

Protein Structural Class

Download Full-text

Partial imputation of unseen records to improve classification using a hybrid multi-layered artificial immune system and genetic algorithm

Applied Soft Computing ◽

10.1016/j.asoc.2013.08.005 ◽

2013 ◽

Vol 13 (12) ◽

pp. 4461-4480 ◽

Cited By ~ 18

Author(s):

Mlungisi Duma ◽

Tshilidzi Marwala ◽

Bhekisipho Twala ◽

Fulufhelo Nelwamondo

Keyword(s):

Genetic Algorithm ◽

Immune System ◽

Artificial Immune System ◽

Artificial Immune

Download Full-text

Distributed Autonomous Robotic System based on Artificial Immune system and Distributed Genetic Algorithm

Journal of Korean institute of intelligent systems ◽

10.5391/jkiis.2004.14.2.164 ◽

2004 ◽

Vol 14 (2) ◽

pp. 164-170 ◽

Cited By ~ 1

Author(s):

Kwee-Bo Sim ◽

Chul-Min Hwang

Keyword(s):

Genetic Algorithm ◽

Immune System ◽

Artificial Immune System ◽

Robotic System ◽

Artificial Immune ◽

Distributed Genetic Algorithm

Download Full-text

An analysis of Artificial Immune System and Genetic Algorithm in urban path planning

IECON 2010 - 36th Annual Conference on IEEE Industrial Electronics Society ◽

10.1109/iecon.2010.5675516 ◽

2010 ◽

Cited By ~ 4

Author(s):

Unnati Ojha ◽

Mo-Yuen Chow

Keyword(s):

Genetic Algorithm ◽

Immune System ◽

Path Planning ◽

Artificial Immune System ◽

Artificial Immune

Download Full-text

Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis

BMC Microbiology ◽

10.1186/s12866-020-01782-y ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Qingqing Guo ◽

Decheng Bi ◽

Mingcan Wu ◽

Boming Yu ◽

Lang Hu ◽

...

Keyword(s):

Nitric Oxide ◽

Immune System ◽

Signaling Pathways ◽

Euglena Gracilis ◽

Mapk Signaling ◽

Regulation Mechanism ◽

Dependent Manner ◽

Raw264.7 Macrophages ◽

Therapeutic Benefits ◽

Mapk Signaling Pathways

Abstract Background Euglena is a new super health food resource that is rich in the natural polysaccharide paramylon, a linear β-1,3-glucan with various biological activities including activity on the immune system in different cell lines and animals. Despite these reports, the immune regulation mechanism of paramylon is still unclear. Results We investigate the signaling pathways paramylon impacts in immune macrophages. In RAW264.7 macrophages, sonicated and alkalized paramylon oligomers up-regulated inducible nitric oxide synthase (iNOS) and increased secretion of nitric oxide (NO), interleukin (IL)-6 and tumor necrosis factor (TNF)-α, in a concentration-dependent manner. In addition, paramylon activated the nuclear factor-κB(NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways and inhibiting these pathways attenuated the paramylon-induced secretion of the above immune-mediators. Conclusions These results demonstrate that Euglena gracilis paramylon modulates the immune system via activation of the NF-κB and MAPK signaling pathways and thus has potential therapeutic benefits.

Download Full-text