EyeXplain Autism: Interactive System for Eye Tracking Data Analysis and Deep Neural Network Interpretation for Autism Spectrum Disorder Diagnosis

2021 ◽  
Author(s):  
Ryan Anthony Jalova de Belen ◽  
Tomasz Bednarz ◽  
Arcot Sowmya
Keyword(s):  
Neural Network ◽  
Autism Spectrum Disorder ◽  
Data Analysis ◽  
Eye Tracking ◽  
Deep Neural Network ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Interactive System ◽  
Tracking Data ◽  
Autism Spectrum Disorder Diagnosis

scholarly journals Computer-Aided Screening of Autism Spectrum Disorder Using Eye-Tracking, Data Visualization and Deep Learning (Preprint)

10.2196/27706 ◽  
2021 ◽  
Author(s):  
Federica Cilia ◽  
Romuald Carette ◽  
Mahmoud Elbattah ◽  
Gilles Dequen ◽  
Jean-Luc Guérin ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Deep Learning ◽  
Eye Tracking ◽  
Data Visualization ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Tracking Data ◽  
Computer Aided

scholarly journals ASD-SAENet: A Sparse Autoencoder, and Deep-Neural Network Model for Detecting Autism Spectrum Disorder (ASD) Using fMRI Data

2021 ◽  
Vol 15 ◽  
Author(s):  
Fahad Almuqhim ◽  
Fahad Saeed
Keyword(s):  
Neural Network ◽  
Autism Spectrum Disorder ◽  
Deep Learning ◽  
Deep Neural Network ◽  
Learning Model ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Fmri Data ◽  
Sparse Autoencoder ◽  
Deep Learning Model

Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder which is characterized by impaired communication, and limited social interactions. The shortcomings of current clinical approaches which are based exclusively on behavioral observation of symptomology, and poor understanding of the neurological mechanisms underlying ASD necessitates the identification of new biomarkers that can aid in study of brain development, and functioning, and can lead to accurate and early detection of ASD. In this paper, we developed a deep-learning model called ASD-SAENet for classifying patients with ASD from typical control subjects using fMRI data. We designed and implemented a sparse autoencoder (SAE) which results in optimized extraction of features that can be used for classification. These features are then fed into a deep neural network (DNN) which results in superior classification of fMRI brain scans more prone to ASD. Our proposed model is trained to optimize the classifier while improving extracted features based on both reconstructed data error and the classifier error. We evaluated our proposed deep-learning model using publicly available Autism Brain Imaging Data Exchange (ABIDE) dataset collected from 17 different research centers, and include more than 1,035 subjects. Our extensive experimentation demonstrate that ASD-SAENet exhibits comparable accuracy (70.8%), and superior specificity (79.1%) for the whole dataset as compared to other methods. Further, our experiments demonstrate superior results as compared to other state-of-the-art methods on 12 out of the 17 imaging centers exhibiting superior generalizability across different data acquisition sites and protocols. The implemented code is available on GitHub portal of our lab at: https://github.com/pcdslab/ASD-SAENet.

Computer-Aided Screening of Autism Spectrum Disorder: Eye-Tracking Study Using Data Visualization and Deep Learning (Preprint)

2021 ◽  
Author(s):  
Federica Cilia ◽  
Romuald Carette ◽  
Mahmoud Elbattah ◽  
Gilles Dequen ◽  
Jean-Luc Guérin ◽  
...  
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Autism Spectrum Disorder ◽  
Eye Tracking ◽  
Convolutional Neural Network ◽  
Visual Representation ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Computer Assisted ◽  
Maximal Information Coefficient

BACKGROUND The early diagnosis of autism spectrum disorder (ASD) is highly desirable but remains a challenging task, which requires a set of cognitive tests and hours of clinical examinations. In addition, variations of such symptoms exist, which can make the identification of ASD even more difficult. Although diagnosis tests are largely developed by experts, they are still subject to human bias. In this respect, computer-assisted technologies can play a key role in supporting the screening process. OBJECTIVE This paper follows on the path of using eye tracking as an integrated part of screening assessment in ASD based on the characteristic elements of the eye gaze. This study adds to the mounting efforts in using eye tracking technology to support the process of ASD screening METHODS The proposed approach basically aims to integrate eye tracking with visualization and machine learning. A group of 59 school-aged participants took part in the study. The participants were invited to watch a set of age-appropriate photographs and videos related to social cognition. Initially, eye-tracking scanpaths were transformed into a visual representation as a set of images. Subsequently, a convolutional neural network was trained to perform the image classification task. RESULTS The experimental results demonstrated that the visual representation could simplify the diagnostic task and also attained high accuracy. Specifically, the convolutional neural network model could achieve a promising classification accuracy. This largely suggests that visualizations could successfully encode the information of gaze motion and its underlying dynamics. Further, we explored possible correlations between the autism severity and the dynamics of eye movement based on the maximal information coefficient. The findings primarily show that the combination of eye tracking, visualization, and machine learning have strong potential in developing an objective tool to assist in the screening of ASD. CONCLUSIONS Broadly speaking, the approach we propose could be transferable to screening for other disorders, particularly neurodevelopmental disorders.

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