Advanced Hemodynamic Monitoring before and after Transjugular Intrahepatic Portosystemic Shunt: Implications for Selection of Patients—A Prospective Study

Radiology ◽  
2012 ◽  
Vol 262 (1) ◽  
pp. 343-352 ◽  
Author(s):  
Bernd Saugel ◽  
Veit Phillip ◽  
Jochen Gaa ◽  
Hermann Berger ◽  
Christian Lersch ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Jiaxiang Meng ◽  
Qing Wang ◽  
Kai Liu ◽  
Shuofei Yang ◽  
Xinxin Fan ◽  
...  

Lipopolysaccharide (LPS) and endothelin- (ET-) 1 may aggravate portal hypertension by increasing intrahepatic resistance and splanchnic blood flow. In the portal vein, after TIPS shunting, LPS and ET-1 were significantly decreased. Our study suggests that TIPS can benefit cirrhotic patients not only in high hemodynamics related variceal bleeding but also in intestinal bacterial translocation associated complications such as endotoxemia.


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