Benign and malignant breast lesions: differentiation with echo-planar MR imaging.

Radiology ◽  
1995 ◽  
Vol 197 (1) ◽  
pp. 33-38 ◽  
Author(s):  
C A Hulka ◽  
B L Smith ◽  
D C Sgroi ◽  
L Tan ◽  
W B Edmister ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast ◽  
Echo Planar

Differentiation between benign and malignant breast lesions with MR imaging and scintimammography.

Radiology ◽  
1997 ◽  
Vol 205 (1) ◽  
pp. 283-283
Author(s):  
F Servais ◽  
D C Blocklet ◽  
A E Seret ◽  
A Lenaers ◽  
A C Schoutens
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast

Differentiation between benign and malignant breast lesions with MR imaging and scintimammography.

Radiology ◽  
1997 ◽  
Vol 205 (1) ◽  
pp. 283-284
Author(s):  
E S Delpassand ◽  
E F Jackson
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast

Value of ductal obstruction sign in the differentiation of benign and malignant breast lesions at MR imaging

2010 ◽  
Vol 75 (2) ◽  
pp. e18-e21 ◽  
Author(s):  
P.A.T. Baltzer ◽  
C.G.N. Kaiser ◽  
M. Dietzel ◽  
T. Vag ◽  
A.B. Herzog ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast

Time-resolved gadolinium-enhanced MR imaging of the breast: Impact on accuracy of diagnosis of breast carcinoma.

2013 ◽  
Vol 31 (26_suppl) ◽  
pp. 33-33
Author(s):  
Hanan Sherif ◽  
Amal Al-Obaidly ◽  
Issam Albosom ◽  
Ahmed-Emad Mahfouz
Keyword(s):  
Breast Carcinoma ◽  
Mr Imaging ◽  
Predictive Value ◽  
Maximum Intensity Projection ◽  
Breast Lesions ◽  
Mr Images ◽  
Time Resolved ◽  
Malignant Breast ◽  
Projection Images ◽  
Malignant Lesions

33 Background: The purpose of the study is to differentiate benign and malignant breast lesions based on very early enhancement of the lesion on time-resolved gadolinium-enhanced MR imaging. Methods: 100 women with breast lesions were examined at 1.5 T (Siemens, Erlangen, Germany), by fast T1-weighted GRE images every 5 s for 1 min after injection of Gd-DOTA (Dotarem, Guerbet, France), followed by 5 spacially-resolved MR image series every 30 s. Images were subtracted; maximum-intensity-projection images were obtained; and images were randomized and reviewed by two blinded readers, who reviewed only the spacially-resolved MR images and gave BIRADS diagnosis. After one month, they evaluated only the time-resolved MR images and noted the time of first appearance of enhancement. Results: The patients had 249 enhancing lesions: 66 malignant on histopathology and 183 benign on basis of histopathology or 1-year imaging follow-up. On time-resolved MR imaging, 15 lesions enhanced at 0-5 s (all malignant), 23 at 5-10 s (21 malignant, 2 benign), 34 at 10-15 s (28 malignant, 6 benign), and 117 at 15-20 s (2 malignant, 115 benign). All malignant lesions enhanced before 20 s. Taking 15s as the cut-off point, early enhancement had sensitivity of 96.9%, specificity of 95.6%, positive predictive value of 88.8%, negative predictive value of 98.8%, and accuracy of 95.9% for diagnosis of carcinoma. Enhancement before 15 s corrected BIRADS diagnosis of the spacially-resolved MR imaging in 14 lesions (5.6%). Conclusions: Lesion enhancement in the first 15s on time-resolved MR imaging is a useful sign for the diagnosis of breast carcinoma.

Mechanism of contrast enhancement in breast lesions at MR imaging

1998 ◽  
Vol 39 (5) ◽  
pp. 494-500 ◽  
Author(s):  
B. Boné ◽  
M. Kristoffersen Wiberg ◽  
C. Parrado ◽  
U. Falkmer ◽  
P. Aspelin ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Contrast Enhancement ◽  
General Mechanism ◽  
Breast Lesions ◽  
Breast Carcinomas ◽  
Malignant Breast ◽  
Nuclear Ploidy ◽  
Invasive Breast Carcinomas ◽  
Benign Tumours ◽  
Parenchymal Cells

Purpose: the aim of the study was to explain why breast lesions are enhanced by contrast medium at MR imaging and to elucidate the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions Material and Methods: Ten invasive breast carcinomas and 10 benign breast lesions were selected for the study. of the 10 carcinomas, 5 showed a strong and early contrast enhancement, and 5 did not. of the 10 benign lesions, 5 showed a strong and early contrast enhancement, and 5 showed no enhancement. the following morphometric variables were evaluated: proliferation cell index of neoplastic parenchymal cells, S-phase fraction, nuclear ploidy analysed by image DNA-cytometry, microvessel density, and the percentage proportion of the interstitial area Results: Contrast enhancement was related to the proliferating activity of the hyperplastic or neoplastic parenchymal cells and was inversely correlated with the interstitial area in carcinomas as well as in benign tumours and non-neo-plastic lesions of the breast Conclusion: Morphometric variables play an important role in the general mechanism of MR contrast enhancement in examinations of the breast and explain the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions

Benign and Malignant Breast Lesions: Diagnosis with Multiparametric MR Imaging

Radiology ◽  
2003 ◽  
Vol 229 (1) ◽  
pp. 225-232 ◽  
Author(s):  
Michael A. Jacobs ◽  
Peter B. Barker ◽  
David A. Bluemke ◽  
Cindy Maranto ◽  
Cheryl Arnold ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast

Differentiation of benign and malignant breast lesions: MR imaging versus Tc-99m sestamibi scintimammography.

Radiology ◽  
1997 ◽  
Vol 202 (2) ◽  
pp. 421-429 ◽  
Author(s):  
T H Helbich ◽  
A Becherer ◽  
S Trattnig ◽  
T Leitha ◽  
P Kelkar ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Malignant Breast

Discrimination between benign and malignant breast lesions using volumetric quantitative dynamic contrast-enhanced MR imaging

2017 ◽  
Vol 28 (3) ◽  
pp. 982-991 ◽  
Author(s):  
Ziliang Cheng ◽  
Zhuo Wu ◽  
Guangzi Shi ◽  
Zhilong Yi ◽  
Mingwei Xie ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced ◽  
Malignant Breast
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