Thoracoabdominal restriction in supine men: CT and lung function measurements

Thoracoabdominal restriction was brought on by means of a corset, and the subsequent effects on thoracic dimensions and lung tissue were studied by computerized tomography (CT) and by various lung function tests in supine healthy volunteers (mean age 30 yr). Restriction caused reductions in total lung capacity (helium equilibration) from mean 6.84 to 4.80 liters, in functional residual capacity (FRC) from 2.65 to 2.08 liters, and in vital capacity from 5.16 to 3.45 liters. Closing capacity (single-breath N2 washout) fell from 2.42 to 1.88 liters, thus matching the reduction in FRC. The static pressure-lung volume curve was shifted to the right by 1.5 cmH2O at 50% of total lung capacity. However, no change in the slope of the curve was observed. The diaphragm was moved cranially by 1.2 cm, and the thoracic cross-sectional area was reduced by a mean 32 cm2 at a level just above the diaphragm. No changes in the lung tissue were seen on CT scanning. Gas exchange, as assessed by multiple inert gas elimination technique and arterial blood gas analysis, was unaffected by restriction. It is concluded that in supine subjects, thoracoabdominal restriction that reduces FRC by 0.6 liter is not accompanied by atelectasis (normal CT scan). In this respect the result differs from that found in anesthetized supine subjects who show the same fall in FRC and atelectasis in dependent lung regions.

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Comparison of oxygen saturation measured by pulse oximetry and arterial blood gas analysis in neonates

Paediatrica Indonesiana ◽

10.14238/pi43.6.2003.211-5 ◽

2016 ◽

Vol 43 (6) ◽

pp. 211

Author(s):

Srie Yanda ◽

Munar Lubis ◽

Yoyoh Yusroh

Keyword(s):

Oxygen Saturation ◽

Pulse Oximetry ◽

Heart Defects ◽

Blood Gas Analysis ◽

Gas Analysis ◽

Blood Oxygenation ◽

Blood Gas ◽

Cross Sectional ◽

Arterial Blood Gas ◽

Arterial Blood

Background Arterial blood gas is usually beneficial to discern thenature of gas exchange disturbances, the effectiveness of com-pensation, and is required for adequate management. AlthoughPaO 2 is the standard measurement of blood oxygenation, oxygensaturation measured by pulse oximetry (SapO 2 ) is now a custom-ary noninvasive assessment of blood oxygenation in newborn in-fants.Objective To compare oxygen saturation measured by pulse oxi-metry (SapO 2 ) and arterial blood gas (SaO 2 ), its correlation withother variables, and to predict arterial partial pressure of oxygen(PaO 2 ) based on SapO 2 values.Methods A cross sectional study was conducted on all neonatesadmitted to Pediatric Intensive Care Unit (PICU) during February2001 to May 2002. Neonates were excluded if they had impairedperipheral perfusion and/or congenital heart defects. Paired t-testwas used to compare SapO 2 with SaO 2 . Correlation between twoquantitative data was performed using Pearson’s correlation. Re-gression analysis was used to predict PaO 2 based on SapO 2 val-ues.Results Thirty neonates were included in this study. The differ-ence between SaO 2 and SapO 2 was significant . There were sig-nificant positive correlations between heart rate /pulse rate andTCO 2 , HCO 3 ; respiratory rate and TCO 2 , HCO 3 , base excess (BE);core temperature and HCO 3 , BE; surface temperature and pH,TCO 2, HCO 3, BE; SapO 2 and pH, PaO 2 ; and significant negativecorrelation between SapO 2 and PaCO 2 ; the correlations were weak.The linear regression equation to predict PaO 2 based on SapO 2values was PaO 2 = -79.828 + 1.912 SapO 2 .Conclusion Pulse oximetry could not be used in place of arterialblood gas analysis available for clinical purpose

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Residual Lung Function Impairment Is Associated with Hyperventilation in Patients Recovered from Hospitalised COVID-19: A Cross-Sectional Study

Journal of Clinical Medicine ◽

10.3390/jcm10051036 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1036

Author(s):

Ernesto Crisafulli ◽

Daniele Gabbiani ◽

Giulia Magnani ◽

Gianluigi Dorelli ◽

Fabiana Busti ◽

...

Keyword(s):

Carbon Monoxide ◽

Lung Function ◽

Clinical Symptoms ◽

Gas Analysis ◽

Cross Sectional ◽

Arterial Blood Gas ◽

Persistent Symptoms ◽

Arterial Blood ◽

Function Impairment ◽

Lung Function Impairment

Patients who have recovered from COVID-19 show persistent symptoms and lung function alterations with a restrictive ventilatory pattern. Few data are available evaluating an extended period of COVID-19 clinical progression. The RESPICOVID study has been designed to evaluate patients’ pulmonary damage previously hospitalised for interstitial pneumonia due to COVID-19. We focused on the arterial blood gas (ABG) analysis variables due to the initial observation that some patients had hypocapnia (arterial partial carbon dioxide pressure-PaCO2 ≤ 35 mmHg). Therefore, we aimed to characterise patients with hypocapnia compared to patients with normocapnia (PaCO2 > 35 mmHg). Data concerning demographic and anthropometric variables, clinical symptoms, hospitalisation, lung function and gas-analysis were collected. Our study comprised 81 patients, of whom 19 (24%) had hypocapnia as compared to the remaining (n = 62, 76%), and defined by lower levels of PaCO2, serum bicarbonate (HCO3−), carbon monoxide diffusion capacity (DLCO), and carbon monoxide transfer coefficient (KCO) with an increased level of pH and arterial partial oxygen pressure (PaO2). KCO was directly correlated with PaCO2 and inversely with pH. In our preliminary report, hypocapnia is associated with a residual lung function impairment in diffusing capacity. We focus on ABG analysis’s informativeness in the follow-up of post-COVID patients.

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Faal Paru Statis

Jurnal Respirasi ◽

10.20473/jr.v2-i.3.2016.91-98 ◽

2019 ◽

Vol 2 (3) ◽

pp. 91

Author(s):

Arief Bakhtiar ◽

Wirya Sastra Amran

Keyword(s):

Lung Function ◽

Functional Residual Capacity ◽

Total Lung Capacity ◽

Normal Lung ◽

Residual Volume ◽

Arterial Blood Gas ◽

Lung Capacity ◽

Arterial Blood ◽

Normal Lung Function ◽

Residual Capacity

Respiration or breathing is the body’s attempt to meet the needs of O2 in the metabolic process and emit CO2 as a result of intermediary metabolism by lung and respiratory organs together so that the resulting cardiovascular oxygen rich blood. Respiration has three phases: ventilation, diffusion, perfusion. The situation is said to somebody normal lung function if the work process of ventilation, diffusion, perfusion, and the relationship between ventilation to perfusion of the person is in a relaxed state resulted in the partial pressure of arterial blood gas (PaO2 and PaCO2) were normal. Examination of lung function has an important role in assessing a lung function. However, the thing to know that these checks are supporting and quite helpful in making a specific diagnosis. With spirometry examination can be known or determined all the static volume except residual volume and respiratory capacity than the capacity of residual volume that contains components such as total lung capacity and functional residual capacity. Functional residual capacity measured by special methods such as by using the inert gas helium (helium dilution test), N2 washout and bodyplethysmograph. Some static pulmonary function parameters can interpret any kind of disturbance in the lungs. In restrictive disorders in general decreased static lung volumes. While the obstruction interference parameters are quite significant, namely an increase in residual volume (RV), functional residual capacity (FRC) and the ratio of residual volume and total lung capacity (RV/TLC)

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Arterial Blood Gas Analysis and the Outcome of Treatment in Tricyclic Antidepressants Poisoned Patients with Benzodiazepine Coingestion

Anesthesiology Research and Practice ◽

10.1155/2015/232401 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Ahmad Yaraghi ◽

Nastaran Eizadi-Mood ◽

Maryam Katani ◽

Shadi Farsaei ◽

Mahrang Hedaiaty ◽

...

Keyword(s):

Tricyclic Antidepressants ◽

Tertiary Care ◽

Blood Gas Analysis ◽

Gas Analysis ◽

University Hospital ◽

Blood Gas ◽

Cross Sectional ◽

Arterial Blood Gas ◽

Arterial Blood ◽

Arterial Ph

Background. Poisoning with tricyclic antidepressants (TCAs) is still a major concern for emergency physicians and intensivists. Concomitant ingestion of other psychoactive drugs especially benzodiazepines with TCAs may make this clinical situation more complex. This study aimed to compare the arterial blood gas (ABG) values and the outcome of treatment in patients with coingestion of TCA and benzodiazepine (TCA + BZD) poisoning and TCA poisoning alone.Methods. In this cross-sectional study which was carried out in a tertiary care university hospital in Iran, clinical and paraclinical characteristics of one hundred forty TCA only or TCA + BZD poisoned patients (aged 18–40 years) were evaluated. ABG analysis was done on admission in both groups. Outcomes were considered as survival with or without complication (e.g., intubation) and the frequency of TCA poisoning complications.Results. Arterial pH was significantly lower in TCA + BZD poisoning group compared with TCA only poisoning group (7.34 ± 0.08 and 7.38 ± 0.08, resp.;P=0.02). However, other complications such as seizure, and the need for the endotracheal intubation were not significantly different. All patients in both groups survived.Conclusions. Concomitant TCA plus BZD poisoning may make the poisoned patients prone to a lower arterial pH level on hospital admission which may potentially increases the risk of cardiovascular complications in TCA poisoning.

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