Role of the Lateral Prefrontal Cortex in Executive Behavioral Control

2008 ◽  
Vol 88 (1) ◽  
pp. 37-57 ◽  
Author(s):  
Jun Tanji ◽  
Eiji Hoshi
Keyword(s):  
Prefrontal Cortex ◽  
Behavioral Control ◽  
Lateral Prefrontal Cortex ◽  
Behavioral Rules ◽  
Neuronal Mechanisms ◽  
Action Sequences ◽  
Cortical Association Areas ◽  
General Aspects ◽  
Prepotent Responses

The lateral prefrontal cortex is critically involved in broad aspects of executive behavioral control. Early studies emphasized its role in the short-term retention of information retrieved from cortical association areas and in the inhibition of prepotent responses. Recent studies of subhuman primates and humans have revealed the role of this area in more general aspects of behavioral planning. Novel findings of neuronal activity have specified how neurons in this area take part in selective attention for action and in selecting an intended action. Furthermore, the involvement of the lateral prefrontal cortex in the implementation of behavioral rules and in setting multiple behavioral goals has been discovered. Recent studies have begun to reveal neuronal mechanisms for strategic behavioral planning and for the development of knowledge that enables the planning of macrostructures of event-action sequences at the conceptual level.

scholarly journals Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Regina C. Lapate ◽  
Jason Samaha ◽  
Bas Rokers ◽  
Bradley R. Postle ◽  
Richard J. Davidson
Keyword(s):  
Prefrontal Cortex ◽  
Metacognitive Awareness ◽  
Social Stimuli ◽  
Lateral Prefrontal Cortex ◽  
Optimal Behavior ◽  
Face Stimuli ◽  
And Function ◽  
Human Faces ◽  
Causal Intervention

AbstractMetacognitive awareness—the ability to know that one is having a particular experience—is thought to guide optimal behavior, but its neural bases continue to be the subject of vigorous debate. Prior work has identified correlations between perceptual metacognitive ability and the structure and function of lateral prefrontal cortex (LPFC); however, evidence for a causal role of this region in promoting metacognition is controversial. Moreover, whether LPFC function promotes metacognitive awareness of perceptual and emotional features of complex, yet ubiquitous face stimuli is unknown. Here, using model-based analyses following a causal intervention to LPFC in humans, we demonstrate that LPFC function promotes metacognitive awareness of the orientation of faces—although not of their emotional expressions. Collectively, these data support the causal involvement of the prefrontal cortex in metacognitive awareness, and indicate that the role of LPFC in metacognition encompasses perceptual experiences of naturalistic social stimuli.

scholarly journals The role of the lateral prefrontal cortex in inhibitory motor control

Cortex ◽  
2013 ◽  
Vol 49 (3) ◽  
pp. 837-849 ◽  
Author(s):  
Ulrike M. Krämer ◽  
Anne-Kristin Solbakk ◽  
Ingrid Funderud ◽  
Marianne Løvstad ◽  
Tor Endestad ◽  
...  
Keyword(s):  
Motor Control ◽  
Prefrontal Cortex ◽  
Lateral Prefrontal Cortex ◽  
Inhibitory Motor Control

T21. Causal Role of the Dorsal-Lateral Prefrontal Cortex in Approach-Avoidance Conflict

2019 ◽  
Vol 85 (10) ◽  
pp. S137
Author(s):  
Noriah Johnson ◽  
Camarin Rolle ◽  
Trevor Caudle ◽  
Marvin Yan ◽  
Amit Etkin
Keyword(s):  
Prefrontal Cortex ◽  
Causal Role ◽  
Lateral Prefrontal Cortex ◽  
Approach Avoidance

Role of the lateral prefrontal cortex in visual object-based selective attention

2009 ◽  
Vol 194 (2) ◽  
pp. 191-196 ◽  
Author(s):  
Scott Sinnett ◽  
Janice J. Snyder ◽  
Alan Kingstone
Keyword(s):  
Prefrontal Cortex ◽  
Selective Attention ◽  
Visual Object ◽  
Lateral Prefrontal Cortex ◽  
Object Based

Life stress, sleep disturbance and depressive symptoms: The moderating role of prefrontal activation during emotion regulation

2021 ◽  
pp. 000486742110257
Author(s):  
Kyung Hwa Lee ◽  
Ha Young Lee ◽  
Inkyung Park ◽  
Jeong Eun Jeon ◽  
Nambeom Kim ◽  
...  
Keyword(s):  
Emotion Regulation ◽  
Prefrontal Cortex ◽  
Depressive Symptoms ◽  
Sleep Disturbance ◽  
Life Stress ◽  
Sleep Problems ◽  
Lateral Prefrontal Cortex ◽  
Moderated Mediation Model ◽  
Moderating Role

Objectives: Evidence suggests that emotion regulation difficulty may play an important role in the association between life stress, sleep disturbance and depressive symptoms. We proposed two models depicting the possible moderating roles of prefrontal cortex activation during emotion regulation in the associations among these variables and tested them. We hypothesized that (1) the association between stress and sleep disturbance would differ across prefrontal cortex activation during emotion regulation (moderation model) and (2) the indirect effects of stress on depressive symptoms through sleep disturbance would depend on prefrontal cortex activation during emotion regulation (moderated mediation model). Methods: Forty-eight healthy adults without sleep disorders based on nocturnal polysomnography participated in this study. They received functional magnetic resonance imaging scans while performing an emotion regulation task. They also completed questionnaires assessing life stress, sleep disturbance and depressive symptoms. The proposed models were tested using the PROCESS macro for SPSS. Results: As hypothesized, there was a significant moderating effect of prefrontal cortex activation during emotion regulation on the association between life stress and sleep disturbance. Furthermore, right lateral prefrontal cortex activation had a moderating role in the indirect effect of life stress on depressive symptoms through sleep disturbance. Conclusion: These findings highlight the important role of prefrontal cortex function during emotion regulation in the associations between stress, sleep disturbance and depressive symptoms. Increasing lateral prefrontal cortex recruitment when regulating the emotional response to negative life events may be critical for the prevention and intervention of depression as well as sleep problems.

scholarly journals Causal role of lateral prefrontal cortex in mental effort and fatigue

2020 ◽  
Vol 41 (16) ◽  
pp. 4630-4640
Author(s):  
Alexander Soutschek ◽  
Philippe N. Tobler
Keyword(s):  
Prefrontal Cortex ◽  
Mental Effort ◽  
Causal Role ◽  
Lateral Prefrontal Cortex
Sign in / Sign up

Export Citation Format

Share Document