Needle Track Seeding of Primary and Secondary Liver Carcinoma After Percutaneous Liver Biopsy

Seeding of tumour in the needle track following percutaneous needle biopsy of liver neoplasms is rarely reported. We describe two such cases following the needle biopsy of an hepatocellular carcinoma and secondary colorectal carcinoma respectively. The risk of needle track recurrence of liver tumours should not be regarded as insignificant. The diagnosis of liver neoplasms may be achieved by non-invasive modalities, and their needle biopsy should be reserved for cases not amenable to surgical resection.

Download Full-text

Post liver transplant presentation of needle-track metastasis of hepatocellular carcinoma following percutaneous liver biopsy

BMJ Case Reports ◽

10.1136/bcr-2013-010076 ◽

2014 ◽

Vol 2014 (jun09 1) ◽

pp. bcr2013010076-bcr2013010076

Author(s):

D. Joyce ◽

G. A. Falk ◽

N. Gandhi ◽

K. Hashimoto

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Biopsy ◽

Liver Transplant ◽

Percutaneous Liver Biopsy ◽

Needle Track

Download Full-text

Needle tract implantation of hepatocellular carcinoma after percutaneous liver biopsy

The American Journal of Surgical Pathology ◽

10.1097/00000478-198303000-00010 ◽

1983 ◽

Vol 7 (2) ◽

pp. 191-196 ◽

Cited By ~ 54

Author(s):

Masami Sakurai ◽

Kouichi Seki ◽

Jun Okamura ◽

Chikazumi Kuroda

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Biopsy ◽

Percutaneous Liver Biopsy ◽

Needle Tract ◽

Needle Tract Implantation

Download Full-text

COMPARISON OF IMAGE FINDINGS WITH HISTOPATHOLOGICAL DIAGNOSIS ON ULTRASOUND GUIDED PERCUTANEOUS LIVER BIOPSY IN RELATION TO HEPATOCELLULAR CARCINOMA

Khyber Medical University Journal ◽

10.35845/kmuj.2018.18102 ◽

2018 ◽

pp. 192-195

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Biopsy ◽

Histopathological Diagnosis ◽

Percutaneous Liver Biopsy ◽

Ultrasound Guided

Download Full-text

RENAL SCARRING SECONDARY TO PERCUTANEOUS NEEDLE BIOPSY

PEDIATRICS ◽

10.1542/peds.38.3.444 ◽

1966 ◽

Vol 38 (3) ◽

pp. 444-447

Author(s):

Yutaka Kikkawa ◽

Ira Greifer ◽

Jay Bernstein ◽

Chester M. Edelmann

Keyword(s):

Late Effects ◽

Needle Biopsy ◽

Renal Scarring ◽

Percutaneous Needle Biopsy ◽

Contralateral Kidney ◽

Needle Track ◽

Vascular Spasm

Focal scarring has been observed in two patients in a second biopsy of the same kidney. It has been attributed to the trauma of the initial puncture, especially to the late effects of vascular spasm and disruption in a zone surrounding the needle track. To prevent confusion in histologic interpretation, the contralateral kidney should be used for a second biopsy.

Download Full-text

Successful Treatment of Dissemination of Hepatocellular Carcinoma to the Pleura and Diaphragm after Percutaneous Liver Biopsy

Digestive Surgery ◽

10.1159/000050137 ◽

2001 ◽

Vol 18 (3) ◽

pp. 225-227 ◽

Cited By ~ 8

Author(s):

Takahiro Uenishi ◽

Shoji Kubo ◽

Kazuhiro Hirohashi ◽

Hiromu Tanaka ◽

Kazuki Ohba ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Biopsy ◽

Successful Treatment ◽

Percutaneous Liver Biopsy

Download Full-text

Lack of Tumor Seeding of Hepatocellular Carcinoma After Percutaneous Needle Biopsy Using Coaxial Cutting Needle Technique

American Journal of Roentgenology ◽

10.2214/ajr.05.1347 ◽

2006 ◽

Vol 187 (5) ◽

pp. 1184-1187 ◽

Cited By ~ 91

Author(s):

Katherine E. Maturen ◽

Hanh V. Nghiem ◽

Jorge A. Marrero ◽

Hero K. Hussain ◽

Ellen G. Higgins ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Needle Biopsy ◽

Percutaneous Needle Biopsy ◽

Tumor Seeding ◽

Needle Technique ◽

Cutting Needle

Download Full-text

Complications and seeding risk after percutaneous liver biopsy in an oncological setting.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.4_suppl.246 ◽

2018 ◽

Vol 36 (4_suppl) ◽

pp. 246-246 ◽

Cited By ~ 1

Author(s):

Katja De Paepe ◽

Lawrence Bonne ◽

Nicos Fotiadis ◽

Naureen Starling ◽

Ian Chau ◽

...

Keyword(s):

Liver Biopsy ◽

Percutaneous Biopsy ◽

Minimal Risk ◽

Percutaneous Liver Biopsy ◽

Ct Guided ◽

Non Invasive ◽

Needle Tract ◽

Invasive Method ◽

Tumor Types

246 Background: Percutaneous biopsy of suspected liver metastases is a common practice for diagnostic purposes. Particularly, in the setting of oncological clinical trials, it is a relatively non-invasive method to obtain sufficient tissue for molecular analyses at regular set time points. However, various complications may occur, including seeding of the tumour along the biopsy tract. Only few reports exist on the actual incidence of seeding, on a limited number of tumor types. The aim of this study was to evaluate the technique’s safety and risk of seeding. Methods: All patients with an ultrasound or CT-guided liver biopsy between 2012-2016 were included. Medical records were reviewed retrospectively for post-biopsy complications and all follow-up imaging was re-assessed for the presence of seeding, defined as tumoral deposits in the biopsy needle tract. Results: In total 782 biopsies were performed in 550 patients (282 women, 268 men; mean age of 61 years), 43.9% (343/782) for trials and 56.1% (439/782) for diagnostic/molecular purposes, 93.7% (733/782) were diagnostic, revealing malignancy in 96.9% (710/733). Number of biopsies per patient ranged between 1 (n=387) to 7 (n=1), a co-axial system was used in 70.6% (552/782) and multiple passes in 29.4% (230/782). Complications were reported in 8.8% (69/782), more often pain (4.7%) and hypotension/vasovagal (2.3%). Admission and/or re-intervention were needed for more severe complications as bleeding (1.0%), sepsis/fever (1.1%), pulmonary embolism (0.3%) and pneumothorax (0.4%). Seeding was seen in 1.1% (8/782) of cases (2/44 melanoma, 1/11 GIST, 1/39 cholangiocarcinoma, 1/247 colorectal, 1/14 oesophagus, 1/97 breast, 1/31 prostate). Mean time for seeding was 208 days (range 43-469 d); mean post-biopsy survival time was 495 days in the seeding and 349 days in the non-seeding group. Conclusions: Percutaneous liver biopsy is a highly effective and safe method for tissue collection, with only a minimal risk of seeding.

Download Full-text