scholarly journals Giant Hepatic Hemangioma With Kasabach–Merritt Syndrome: Is the Appropriate Treatment Enucleation or Liver Transplantation?

HPB Surgery ◽  
2000 ◽  
Vol 11 (6) ◽  
pp. 413-419 ◽  
Author(s):  
Steven N. Hochwald ◽  
Leslie H. Blumgart
Keyword(s):  
Liver Transplantation ◽  
Hepatic Hemangioma ◽  
Preoperative Preparation ◽  
Abdominal Girth ◽  
Disseminated Intravascular Coagulopathy ◽  
Postoperative Course ◽  
Appropriate Treatment ◽  
Intravascular Coagulopathy ◽  
Giant Hepatic Hemangioma ◽  
Hepatic Hemangiomas

We present a case of giant cavernous hemangioma of the liver with disseminated intravascular coagulopathy (Kasabach–Merritt syndrome) which was cured by enucleation. The 51 year old woman presented with increased abdominal girth and easy bruisability. Workup elsewhere revealed a massive hepatic hemangioma and she was started on radiation therapy to the lesion and offered an orthotopic liver transplant. After careful preoperative preparation, we felt that resection was possible and she underwent a successful enucleation. The operation and postoperative course were complicated by bleeding but she recovered and remains well in followup after 6 months. All coagulation parameters have returned to normal. Enucleation should be considered the treatment of choice for hepatic hemangiomas, including those presenting with Kasabach–Merritt syndrome. The benefits of enucleation as compared to liver transplantation for these lesions are discussed.

scholarly journals Giant Hepatic Hemangioma Regressed Significantly Without Surgical Management: A Case Report and Literature Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Jingcong Zhang ◽  
Zuyang Ye ◽  
Lei Tan ◽  
Jinmei Luo
Keyword(s):  
Cell Proliferation ◽  
Liver Transplantation ◽  
Case Report ◽  
Literature Review ◽  
Lymphatic Vessels ◽  
Vascular Anomaly ◽  
Endothelial Cell Proliferation ◽  
Hepatic Hemangioma ◽  
Specific Drug ◽  
Giant Hepatic Hemangioma

Hepatic hemangioma (HH) is a congenital vascular anomaly comprising networks of abnormal blood and/or lymphatic vessels with endothelial cell proliferation. Their pathophysiology is not fully understood, and no specific drug is available to treat them. Conservative management, which limits observation, is preferred for most patients. A HH larger than 4 cm is considered a giant HH that may be treated using surgery ranging from embolization to hepatic resection or liver transplantation. Here, we describe a case with multiple and giant HHs that regressed significantly after treatment with azithromycin (AZM). A systematic literature review of HH and the effects of AZM on angiogenesis was then conducted.

scholarly journals Orthotophic Liver Transplantation in Giant Hepatic Hemangioma: A Case Report and Literature Review

2013 ◽  
Vol 03 (03) ◽  
pp. 47-49
Author(s):  
Jessica Casella ◽  
Carla Lemos Gottgroy ◽  
Carlos Rocha Maia ◽  
Felipe Pedreira Tavares de Mello ◽  
Samanta Teixeira Basto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Literature Review ◽  
Hepatic Hemangioma ◽  
Giant Hepatic Hemangioma

Liver Transplantation for Rapidly Progressive Giant Hepatic Hemangioma With Diffuse Hemangiomatosis

2021 ◽  
Author(s):  
Sadhana Shankar ◽  
Ashwin Rammohan ◽  
Venugopal H. Kulaseharan ◽  
Rathnavel Kanagavelu ◽  
Mettu S. Reddy ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatic Hemangioma ◽  
Giant Hepatic Hemangioma

scholarly journals Giant Pedunculated Hepatic Hemangioma: A Case Report and Literature Review

2018 ◽  
Vol 11 (2) ◽  
pp. 476-484 ◽  
Author(s):  
Abdallah  Al Farai ◽  
Lénaïg Mescam ◽  
Valeria De Luca ◽  
Audrey Monneur ◽  
Delphine Perrot ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Preoperative Diagnosis ◽  
English Literature ◽  
Hepatic Hemangioma ◽  
Hepatic Lobectomy ◽  
Pathological Analysis ◽  
Left Hepatic Lobectomy ◽  
Giant Hepatic Hemangioma ◽  
Hepatic Hemangiomas

Hepatic hemangioma is the most common benign hepatic tumor, and most of them are small in size and asymptomatic. Giant hepatic hemangiomas are uncommon, but pedunculated giant hemangiomas are even rarer and often difficult to diagnose because of their exophytic development. We report here on a 48-year-old man with a symptomatic pedunculated giant hepatic hemangioma and hepatic angiomatosis, mimicking a gastric gastrointestinal stromal tumor with liver metastases. The preoperative diagnosis was suspected on imaging including CT scan and MRI. The patient was successfully operated (left hepatic lobectomy), without any complication, and the pathological analysis confirmed the diagnosis. We reviewed the English literature, and to our knowledge, our case represents the largest case reported so far when compared with the 19 other informative cases.

scholarly journals Treatment of a Giant Haemangioma of the Liver With Kasabach-Merritt Syndrome by Orthotopic Liver Transplant

HPB Surgery ◽  
1997 ◽  
Vol 10 (3) ◽  
pp. 159-162 ◽  
Author(s):  
J-H. Longeville ◽  
P. De La M. Hall ◽  
P. Dolan ◽  
A. W. Holt ◽  
P. E. Lillie ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Resection ◽  
Liver Transplant ◽  
Initial Treatment ◽  
Tooth Extraction ◽  
Orthotopic Liver Transplant ◽  
Cavernous Haemangioma ◽  
Disseminated Intravascular Coagulopathy ◽  
Intravascular Coagulopathy ◽  
Hepatic Haemangioma

We describe a case of giant cavernous haemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by orthotopic liver transplant.A 47 year old man presented with bleeding and tender massive hepatomegaly after tooth extraction. Investigations showed disseminated intravascular coagulopathy and a giant hepatic haemangioma involving both lobes of the liver. Initial treatment failed to resolve the coagulopathy and liver resection was attempted. At laparotomy the turnout was unresectable and the only option for cure was to offer a liver transplantation. The orthotopic liver transplant was performed 20 days after initial laparotomy. Subsequently, all coagulation parameters returned to normal and the patient remains well after 12 months. Orthotopic liver transplant can be considered for giant hepatic haemangioma with Kasabach-Merritt syndrome when resection is necessary and a partial hepatectomy is not technically feasible.

scholarly journals Totally Laparoscopic Resection of an Extremely Giant Hepatic Hemangioma

2019 ◽  
Vol 05 (03) ◽  
pp. e110-e112 ◽  
Author(s):  
Fadl H. Veerankutty ◽  
Shiraz Ahmad Rather ◽  
Varghese Yeldho ◽  
Bincy M. Zacharia ◽  
Shabeer Ali TU ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Anterior Approach ◽  
Laparoscopic Resection ◽  
Hepatic Hemangioma ◽  
Laparoscopic Treatment ◽  
Open Resection ◽  
Totally Laparoscopic ◽  
Giant Hepatic Hemangioma ◽  
Hepatic Hemangiomas

AbstractRisk of massive intraoperative hemorrhage and the difficulty to control it makes the laparoscopic treatment of giant hepatic hemangiomas (GH) a challenge for minimally invasive hepatobiliary surgeons. Symptomatic GHs of more than 20 cm (extremely giant hepatic hemangiomas) are typically treated with an open resection. There is a paucity of literature on laparoscopic resection of extremely giant hepatic hemangiomas. We describe (with video), here, the technical nuances of pure laparoscopic resection of an extremely giant hepatic hemangioma using modified port positions and the anterior approach.

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