scholarly journals Synthesis, Characterization and Antifungal Activity of Novel Quinazolin-4-one Derivatives Containing 8-Hydroxyquinazoline Ligand and its Various Metal Complexes

2009 ◽  
Vol 6 (s1) ◽  
pp. S445-S451
Author(s):  
R. T. Vashi ◽  
S. B. Patel
Keyword(s):  
Antifungal Activity ◽  
Elemental Analysis ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Distorted Octahedral Geometry ◽  
Hydroxyl Groups ◽  
Tetrahedral Geometry ◽  
Distorted Octahedral ◽  
Metal Ligand ◽  
Methyl Phenyl

Novel ligands containing quinazoline-4-one-8-hydroxyquinoline (QQ) merged moieties were prepared and characterized. For this anthranilic acid and 5-bromoanthranilic acid were converted respectively into 2-chloromethyl–3-(4-methyl phenyl)-3(H)-quinazoline-4-one and 2-chloromethyl–3-(methyl phenyl)-6-bromo-3(H)-quinazoline-4-one. Both these compounds were condensed with 5-amino-8-hydroxyquinoline. The so called resulted compounds were named respectively as 2-[(8-hydroxy-quinolinyl) –5- amino methyl] -3-(4-methylphenyl)- 3(H)- quinazoline -4- one and 2-[(8-hydroxyquinolinyl)-5-aminomethyl] -3(methyl phenyl)-6-bromo-3(H)-quinazoline-4-one. Both the compounds were designated respectively as HL1and HL2ligands. The transition metal (Cu2+, Ni2+, Zn2+, Mn2+and Co2+) complexes of both these ligands were prepared. The ligands and their complexes as case may be were characterized by elemental analysis, spectral studies and number of hydroxyl groups. The stoichiometry of the complexes has been found to be 1:2 (metal: ligand). An octahedral geometry around Co2+, Ni2+and Mn2+, distorted octahedral geometry around Cu2+and tetrahedral geometry of around Zn2+have been proposed. These complexes also been tested for their antifungal activities.

scholarly journals Synthesis, Spectroscopic Studies and Antifungal Activity of 2-[(4(3-Chlorophenyl) piperazine-1-yl)methyl]-3-[8-hydroxy quinolin-5-yl]-3(H)-quinazolin-4-one Ligand and its Chelates

2010 ◽  
Vol 7 (s1) ◽  
pp. S163-S168 ◽  
Author(s):  
R. T. Vashi ◽  
C. D. Shelat ◽  
Himanshu Patel
Keyword(s):  
Antifungal Activity ◽  
Spectroscopic Studies ◽  
Metal Chelates ◽  
Octahedral Geometry ◽  
Distorted Octahedral Geometry ◽  
Tetrahedral Geometry ◽  
Transition Metal Chelates ◽  
Distorted Octahedral ◽  
Ft Ir ◽  
Physicochemical Methods

The novel ligand HL6was synthesized using anthranilic acid and it was undergo the chelating reaction with Cu(II), Ni(II), Co(II), Mn(II) and Zn(II) to prepare transition metal chelates. These chelates were characterized by physicochemical methods such as elemental analysis, conductometric studies, magnetic susceptibility, FT-IR, NMR and electronic spectra. The stoichiometry of the complexes has been found to be 1: 2 (Metal: ligand). An octahedral geometry around Co(II), Ni(II) and Mn(II), distorted octahedral geometry around Cu(II) and tetrahedral geometry around Zn(II) have been proposed. The antifungal activity of ligand and its metal chelates were conducted against various fungi.

scholarly journals Bis[tetrakis(pyridin-2-yl)methane-κ3N,N′,N′′]cobalt(II) tetrakis(thiocyanato-κN)cobaltate(II) methanol monosolvate

2014 ◽  
Vol 70 (3) ◽  
pp. m96-m97 ◽  
Author(s):  
Yuya Tsunezumi ◽  
Kouzou Matsumoto ◽  
Shinya Hayami ◽  
Akira Fuyuhiro ◽  
Satoshi Kawata
Keyword(s):  
Complex Anion ◽  
Complex Cation ◽  
Solvent Molecule ◽  
Octahedral Geometry ◽  
Title Complex ◽  
Distorted Octahedral Geometry ◽  
Weak Hydrogen Bond ◽  
Tetrahedral Geometry ◽  
Distorted Tetrahedral Geometry ◽  
Distorted Octahedral

The title complex, [Co(C21H16N4)2][Co(NCS)4]·CH3OH, consists of one [Co{C(py)4}2]2+complex cation [C(py)4= tetrakis(pyridin-2-yl)methane], one [Co(NCS)4]2−complex anion and a methanol solvent molecule. In the cation, the CoIIatom is coordinated by six N atoms of two C(py)4ligands in a distorted octahedral geometry. In the anion, the CoIIatom is coordinated by the N atoms of four NCS−ligands in a distorted tetrahedral geometry. The methanol molecule is disordered and was modelled over three orientations (occupancies 0.8:0.1:0.1). There are two weak hydrogen-bond-like interactions between the methanol solvent molecule and NCS−ligands of the anion [O...S = 3.283 (3) and 3.170 (2) Å].

scholarly journals Synthesis, Characterization and Antifungal Studies of Adducts of p- Ethylphenyldithiocarbonates of Copper(II)

2019 ◽  
Vol 31 (8) ◽  
pp. 1819-1824
Author(s):  
Shivangi Sharma ◽  
Renu Sachar ◽  
G.D. Bajju ◽  
Vikas Sharma
Keyword(s):  
Magnetic Susceptibility ◽  
Electron Spin Resonance ◽  
Room Temperature ◽  
Molar Conductance ◽  
Octahedral Geometry ◽  
Molar Ratio ◽  
Spectral Studies ◽  
Distorted Octahedral Geometry ◽  
Distorted Octahedral ◽  
Spin Resonance

A series of adducts of p-ethylphenyldithiocarbonates of copper(II) [(p-C2H5C6H4OCS2)2Cu] with ethyl pyridines and chloro pyridines have been synthesized in 1:2 molar ratio. They were characterized by elemental analysis, magnetic susceptibility and molar conductance measurements, infrared, electronic, electron spin resonance and mass spectroscopy, NMR and thermogravimetric analysis. In addition, antifungal studies of these adducts were also performed. The results revealed that the adducts have 1:2 stoichiometry, non-electrolytic and paramagnetic at room temperature. On the basis of spectral studies, a distorted octahedral geometry is proposed around copper(II) ion. ESR studies depicted elongated axial symmetry of Cu(II)adducts with nitrogen donors. Moreover, the adducts also showed potential antifungal activity against Fusarium oxysporium.

SYNTHESIS AND CHARACTERIZATION OF TI (III), V (III),VO (IV), MOO (V),FE (II) AND FE (III) COMPLEXES OF BENZIL- 2,4-DINITROPHENYL HYDRAZONE P-BROMO ANILINE

2016 ◽  
Vol 2 (4) ◽  
pp. 177
Author(s):  
Raj Kamal Rastogi ◽  
Sonu Sharma ◽  
Gulshan Rastogi ◽  
Alok K. Singh
Keyword(s):  
Elemental Analysis ◽  
Magnetic Measurement ◽  
Measurement Data ◽  
Molar Conductance ◽  
Octahedral Geometry ◽  
Synthesis And Characterization ◽  
Distorted Octahedral Geometry ◽  
Distorted Octahedral ◽  
Uv Visible

The complexes of Benzil-2, 4-dinitrophenyl hydrazone-p- bromo aniline with Ti(III),V(III), VO(IV),MoO (V), Fe(II), Fe(III) have synthesized and characterized by elemental analysis, magnetic measurement data, molar conductance, TGA,UV-visible and IR spectra data. The complexes of Ti (III), V (III), Fe (II) and Fe (III) have octahedral geometry while VO (IV) and MoO(V) have distorted octahedral geometry due to the presence of M=O moiety.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Metal Chelates of 5-[1(H)-Benzotriazole methylene]-8-quinolinol

2009 ◽  
Vol 6 (2) ◽  
pp. 371-376 ◽  
Author(s):  
H. S. Patel ◽  
K. K. Oza
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Properties ◽  
Antifungal Activity ◽  
Elemental Analysis ◽  
Potassium Carbonate ◽  
Antifungal Agents ◽  
Metal Chelates ◽  
Spectral Studies ◽  
Transition Metal Chelates ◽  
Metal Ligand

5-Chloromethyl-8-quinolinol was condensed stoichiometrically with benzotriazole in presence of potassium carbonate. The resulting 5-[1(H)-benzo triazole methylene]-8-quinolinol (BTMQ) was characterized by elemental analysis and spectral studies. The transition metal chelatesviz. Cu2+, Ni2+, Co3+, Mn2+and Zn2+of BTMQ were prepared and characterized by metal-ligand (M:L) ratio, IR and reflectance spectral studies and magnetic properties. The antifungal activity of BTMQ and its metal chelates was screened against various fungi. The results show that all these samples are good antifungal agents.

scholarly journals Molybdenum(VI) Complexes with Schiff Base Containing N-Hetero Atom

2020 ◽  
Vol 10 (1) ◽  
pp. 1816-1824
Keyword(s):  
Schiff Base ◽  
Octahedral Geometry ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Distorted Octahedral Geometry ◽  
Tetradentate Ligand ◽  
Molybdenum Complex ◽  
Molybdenum Complexes ◽  
Distorted Octahedral ◽  
Elemental Analyses

Parent dioxomolybdenum(VI) complex formation by the reaction of MoO2(acac)2 with Schiff base tetradentate ligand, described in this paper. Schiff base tetradentate ligand [H2NCH2CH2 N=CC4H3S-CC4H3S=NCH2CH2NH2] obtained from the condensation of di-2-thienylethanedione with 1,2-diaminoethane. Macrocyclic molybdenum complexes were obtained from the cyclization of a synthesized complex with different 1,3 – diketones. The general formula of parent molybdenum complex is given as [MoO2( H2NCH2CH2 N=CC4H3S – CC4H3S=N CH2CH2NH2)](acac)2 and for macrocyclic molybdenum complex is [MoO2{(CH2CH2 N=CC4H3S – CC4H3S=N CH2CH2) N=C(R)CH2C(R’)=N}](acac)2. Ligand and all molybdenum complexes were characterized by elemental analyses(EA), molar conductivity(ΛM), ultraviolet(UV-Vis), and infrared (IR) spectral studies. The distorted octahedral geometry of element Mo in the parent as well as in macrocyclic molybdenum complexes is completed by two oxo O-atoms, four N-atoms from derived Schiff ligand.

Bis(2,2′-bipyridine-κ2 N,N′)bis(4-hydroxybenzoato-κO)manganese(II)

2006 ◽  
Vol 62 (4) ◽  
pp. m712-m713 ◽  
Author(s):  
Zi-Qiang Hu ◽  
Lian-Bin Wu ◽  
Guo-Qiao Lai
Keyword(s):  
Hydrogen Bonding ◽  
Octahedral Geometry ◽  
Distorted Octahedral Geometry ◽  
Hydroxyl Groups ◽  
Twofold Axis ◽  
Distorted Octahedral

The title MnII complex, [Mn(C7H5O3)2(C10H8N2)2], has twofold symmetry, with the MnII atom located on a twofold axis. Two 4-hydroxybenzoate anions and two 2,2′-bipyridine coordinate to the MnII atom which has a distorted octahedral geometry. Hydrogen bonding between the carboxylate and hydroxyl groups forms a sheet perpendicular to the a axis.

scholarly journals STUDIES ON N-[2-THIENYLMETHYLIDENE)-2-AMINOPYRIDINE COMPLEXES OF Fe(II), Co(II), Ni(II), Cu(II), Zn(II) AND Cd(II)

2001 ◽  
Vol 9 (10) ◽  
pp. 17-22
Author(s):  
Cezar Spinu ◽  
Angela Kriza ◽  
Aurelia Meghea ◽  
Cristian Tigae
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Nmr Spectra ◽  
Thiophene Ring ◽  
Spectral Studies ◽  
Octahedral Structure ◽  
Tetrahedral Geometry ◽  
Ir And Nmr Spectra ◽  
Distorted Octahedral

Metal complexes ML2Cl2, where M is Fe(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) and L is Schiff base formed by condensation of 2-thiophenecarboxaldehyde and 2-aminopyridine, N-[2-thienylmethylidene]-2-arninopyridine (TNAPY), have been prepared and characterized by elemental analysis, magnetic and spectroscopic measurements. IR and NMR spectra show that the nitrogen of the azomethyne group and the sulphur of the thiophene ring take part in coordination. Magnetic, ESR and electronic spectral studies show a distorted octahedral structure for the Fe(II), Co(II), Ni(II) and Cu(II) complexes and a tetrahedral geometry for the Zn(II) and Cd(II) complexes. Conductance measurements suggest the non-electrolytic nature of the complexes, with the exception of the Zn(TNAPY)2Cl2 and Cd(TNAPY)2Cl2 compounds which are 1:2 electrolytes.

scholarly journals Bis[trans-difluoridotetrakis(pyridine-κN)chromium(III)] sodium tetrachloridozincate perchlorate from synchrotron data

2014 ◽  
Vol 70 (7) ◽  
pp. m280-m280 ◽  
Author(s):  
Dohyun Moon ◽  
Keon Sang Ryoo ◽  
Jong-Ha Choi
Keyword(s):  
Hydrogen Bonds ◽  
Crystal Packing ◽  
Octahedral Geometry ◽  
Distorted Octahedral Geometry ◽  
Tetrahedral Geometry ◽  
Bond Lengths ◽  
Distorted Tetrahedral Geometry ◽  
Distorted Octahedral ◽  
The Mean ◽  
Supramolecular Chains

The title salt, Na[CrF2(C5H5N)4]2[ZnCl4]ClO4, consists of two cationic CrIIIcomplexes, an Na+cation, one [ZnCl4]2−anion and one ClO4−anion. The CrIIIatoms are coordinated by four pyridine (py) N atoms and two F atoms in atransarrangement, displaying a distorted octahedral geometry. The mean Cr—N(py) and Cr—F bond lengths are 2.086 (8) and 1.864 (14) Å, respectively. The [ZnCl4]2−anion has a distorted tetrahedral geometry. The most notable feature of the crystal packing is the formation of weak pyridine–perchlorate C—H...O hydrogen bonds, resulting in supramolecular chains along theb-axis direction. The perchlorate anion was disordered over two sets of sites in a 0.868 (3):0.132 (3) ratio.

scholarly journals Crystal structure of bis[trans-(ethane-1,2-diamine-κ2N,N′)bis(thiocyanato-κN)chromium(III)] tetrachloridozincate from synchrotron data

2015 ◽  
Vol 71 (1) ◽  
pp. 100-103 ◽  
Author(s):  
Dohyun Moon ◽  
Jong-Ha Choi
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Octahedral Geometry ◽  
Distorted Octahedral Geometry ◽  
Inversion Symmetry ◽  
Asymmetric Unit ◽  
Intermolecular Hydrogen Bonds ◽  
Tetrahedral Geometry ◽  
Distorted Tetrahedral Geometry ◽  
Distorted Octahedral

The structure of the title compound, [Cr(NCS)2(C2H8N2)2]2[ZnCl4], has been determined from synchrotron data. In the asymmetric unit, there are four independent halves of the CrIIIcomplex cations, each of which lies on an inversion centre, and one tetrachloridozincate anion in a general position. The CrIIIatoms are coordinated by the four N atoms of two ethane-1,2-diamine (en) ligands in the equatorial plane and two N-bound NCS−anions in atransarrangement, displaying a slightly distorted octahedral geometry with crystallographic inversion symmetry. The Cr—N(en) and Cr—N(NCS) bond lengths range from 2.0653 (10) to 2.0837 (10) Å and from 1.9811 (10) to 1.9890 (10) Å, respectively. The five-membered metalla-rings are in stablegaucheconformations. The [ZnCl4]2−anion has a distorted tetrahedral geometry. The crystal structure is stabilized by intermolecular hydrogen bonds involving the en NH2or CH2groups as donors and chloride ligands of the anion and S atoms of NCS−ligands as acceptors.

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