An Osmium(VI) Nitride Triggers Mitochondria-induced Oncosis and Apoptosis

We report a new osmium(VI) nitrido complex bearing a nonplanar tetradentate ligand with potent anticancer activity. It causes mitochondrial damage, which induces liver cancer cell death via oncosis and apoptosis....

A Highly Durable, Self-Photosensitized Mononuclear Ruthenium Catalyst for CO2 Reduction

A novel mononuclear ruthenium (Ru) complex bearing a PNNP-type tetradentate ligand is introduced here as a self-photosensitized catalyst for the reduction of carbon dioxide (CO2). When the pre-activation of the Ru complex by reaction with a base was carried out, an induction period of catalyst almost disappeared and the catalyst turnover numbers (TONs) over a reaction time of 144 h reached 307 and 489 for carbon monoxide (CO) and for formic acid (HCO2H), respectively. The complex has a long lifespan as a dual photosensitizer and reduction catalyst, due to the sterically bulky and structurally robust (PNNP)Ru framework. Isotope labeling experiments under 13CO2 atmosphere indicate that CO and HCO2H were both produced from CO2.