Hepatitis C and Kidney Disease

Multiple extrahepatic manifestations have been associated with chronic hepatitis C, the most important among them being cryoglobulinemia, glomerulonephritis, porphyria cutanea tarda, lichen planus, seronegative arthritis, and lymphoproliferative disorders as in the sudies of Bonkovsky and Mehta (2001) and El-Serag et al. (2002). We will discuss in this paper chronic hepatitis C- related kidney disease and course and management of patients with chronic hepatitis C in special circumstances like hemodialysis and kidney transplantation.

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Therapy with DAAs in patients with chronic hepatitis C and advanced chronic kidney disease: Real-world experience of the German Hepatitis C Registry

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612875 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

J Wiegand ◽

P Buggisch ◽

S Mauss ◽

K Böker ◽

H Klinker ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Chronic Hepatitis ◽

Hepatitis C ◽

Kidney Disease ◽

Chronic Hepatitis C ◽

Real World ◽

Advanced Chronic Kidney Disease

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The Effects of Interferon and Ribavirin in Chronic Hepatite C

Revista de Chimie ◽

10.37358/rc.17.9.5844 ◽

2017 ◽

Vol 68 (9) ◽

pp. 2147-2150

Author(s):

Liliana Coldea ◽

Florin Grosu ◽

Alina Liliana Pintea ◽

Sebastian Ioan Cernusca Mitariu ◽

Nicolae Grigore ◽

...

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Chronic Hepatitis C ◽

Antiviral Treatment ◽

Public Health Problem ◽

Complete Response ◽

Extrahepatic Manifestations ◽

Hépatite C ◽

Response Versus

The chronic hepatitis C is a frequently problem in worldwide, the number of infected individuals is high and go on, getting a public health problem [1]. In Romania there are nearly 1 million persons infected with hepatitis C virus, the scope of spreading is related with specific risk factors. An important number of infection with hepatitis C virus present simultaneous extrahepatic manifestations proved to be alone manifestation tracing; its important for diagnosis and treatment. We analyzed the effects of interferon and ribavirin in chronic hepatitis C in General C.F. Hospital Sibiu, between 2008 � 2012. The association between infection with hepatitis C virus and extrahepatic manifestations is important to be recognized for adequate diagnosis tests. By comparing the results of therapy in patients with hepatic and extrahepatic manifestations, the study found that 30 patients (58.83 %) with liver manifestations had an incomplete response versus 10 patients (26.32 %) with extrahepatic manifestations; 11 patients (21.54 %) with hepatic manifestations had a complete response versus 3 patients (7.89 %) with extrahepatic manifestations; and 10 patients (19.63 %) with hepatic manifestations did not respond to treatment versus 25 patients (65.79 %) with extrahepatic manifestations. Analyzing the results of antiviral therapy in patients with hepatic manifestations and those with extrahepatic manifestations, antiviral treatment appears to be more advantageous in cases with only hepatic manifestations.

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