scholarly journals Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Fayçal Lakhdar ◽  
El Mehdi Hakkou ◽  
Rachid Gana ◽  
Rachid My Maaqili ◽  
Fouad Bellakhdar

Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.

Neurographics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 59-62
Author(s):  
A.M. Romesberg ◽  
A.A. Roney ◽  
D.E. Lukins

Intracranial epidermoid cysts represent a group of relatively common, benign, indolent tumors most frequently encountered at the cerebellopontine angle. Presentation is usually secondary to compressive neurologic symptoms. Treatment is surgical debulking and generally is curative. As with other epidermoid cysts throughout the body, the risk of degeneration into squamous cell carcinoma is a rare complication that is typically fatal within the CNS.


Author(s):  
Abhinav Srivastava ◽  
Ranjan Agrawal ◽  
Prashant Bhardwaj

ABSTRACT Epidermoid cysts are common lesions, but malignant transformation of their epithelium is rare. There are few case reports in the literature concerning malignant transformation of an epidermal cyst into squamous cell carcinoma. Two epidermoid cysts occurring simultaneously in the neck is rare and not a single case report is available in the literature. One of the cysts transforming into squamous cell carcinoma and the other showing atypical changes is still the rarest and not reported till date. We present a case of two epidermal inclusion cysts in a patient out of which there were atypical changes in one cyst and other cyst showed squamous cell carcinoma. How to cite this article Mohan C, Srivastava A, Agrawal R, Bhardwaj P. A Rare Case of Epidermoid Cyst in Neck. Int J Adv Integ Med Sci 2016;1(1):15-17.


2019 ◽  
Vol 9 ◽  
Author(s):  
Joshua A. Cuoco ◽  
Cara M. Rogers ◽  
Christopher M. Busch ◽  
Lisa S. Apfel ◽  
John J. Entwistle ◽  
...  

2019 ◽  
Vol 161 (9) ◽  
pp. 1829-1834 ◽  
Author(s):  
Mina M. Gerges ◽  
Saniya S. Godil ◽  
Kavelin Rumalla ◽  
Benjamin Liechty ◽  
David J. Pisapia ◽  
...  

2010 ◽  
Vol 2 (3) ◽  
pp. 259-261
Author(s):  
Jagadish Tubachi ◽  
Arsheed Hussain Hakeem ◽  
Rajay Ramesh Kumar ◽  
Satish Pawar

Abstract Very few cases of spontaneous malignant transformation of nonirradiated recurrent juvenile laryngeal papillomatosis (JLP) have been reported in literature. We document a case of invasive laryngeal carcinoma arising in pre-existing juvenile laryngeal papillomatosis. After multiple CO2 Laser resections, a 29-year-old female, non-smoker, who had never received radiation therapy, developed a florid exophytic transglottic squamous cell carcinoma. Therefore, regular extensive biopsies and careful histopathological examination are required in cases of JLP. We also emphasize the need to maintain a high index of suspicion for malignant transformation in long standing cases.


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