scholarly journals Functional Magnetic Resonance Imaging for Language Mapping in Temporal Lobe Epilepsy

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
An Wang ◽  
Terry M. Peters ◽  
Sandrine de Ribaupierre ◽  
Seyed M. Mirsattari
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Wada Test ◽  
Language Mapping ◽  
Noninvasive Technique

Functional magnetic resonance imaging (fMRI) is a noninvasive technique that is increasingly used to understand the cerebral cortical networks and organizations. In this paper, we describe the role of fMRI for mapping language networks in the presurgical workup of patients with medically intractable temporal lobe epilepsy (TLE). Studies comparing fMRI with the intracarotid sodium amobarbital (Wada) test and fMRI with intraoperative cortical stimulation mapping for language lateralization and/or localization in medically intractable TLE are discussed.

scholarly journals Dissociating Confidence and Accuracy: Functional Magnetic Resonance Imaging Shows Origins of the Subjective Memory Experience

2004 ◽  
Vol 16 (7) ◽  
pp. 1131-1142 ◽  
Author(s):  
Elizabeth F. Chua ◽  
Erin Rand-Giovannetti ◽  
Daniel L. Schacter ◽  
Marilyn S. Albert ◽  
Reisa A. Sperling
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Objective Measures ◽  
Correct Identification ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
High Confidence

Successful memory typically implies both objective accuracy and subjective confidence, but there are instances when confidence and accuracy diverge. This dissociation suggests that there may be distinct neural patterns of activation related to confidence and accuracy. We used event-related functional magnetic resonance imaging to study the encoding of novel face–name associations, assessed with a postscan memory test that included objective measures of accuracy and subjective measures of confidence. We showed specific neural activity in the left inferior prefrontal cortex associated with trials when subjects expressed high confidence that they had chosen the correct name for the face and made a correct identification. Moreover, we found that this region was also associated with imparting high confidence when subjects chose the incorrect name. However, medial temporal lobe regions showed activity only for high-confidence correct trials. Many functional magnetic resonance imaging studies have shown that the medial temporal lobe and left prefrontal regions are particularly important for the successful formation of memories by using a combination of subjective and objective measures. Our findings suggest that these regions may be differentially involved in the objective and subjective components of memory and that the origins of confidence–accuracy dissociations may be related to incomplete activation of the neural pattern seen in successful encoding. These findings may also aid understanding of eyewitness misidentifications and memory distortions.

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