scholarly journals Rhabdomyolysis and Dengue Fever: A Case Report and Literature Review

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Tanya Sargeant ◽  
Tricia Harris ◽  
Rohan Wilks ◽  
Sydney Barned ◽  
Karen Galloway-Blake ◽  
...  

The medical literature contains only a few reports of rhabdomyolysis occurring in patients with dengue fever. We report the case of a 25-year-old Jamaican man who was admitted to a private hospital four days after the onset of an acute febrile illness with fever, myalgia, and generalized weakness. Dengue fever was confirmed with a positive test for the dengue antigen, nonstructural protein 1. He remained well and was discharged on day 6 of his illness. On day 8, he started to pass red urine and was subsequently admitted to the University Hospital of the West Indies. On admission he was found to have myoglobinuria and an elevated creatine phosphokinase (CPK) of 325,600 U/L, leading to a diagnosis of rhabdomyolysis. Dengue IgM was positive. He was treated with aggressive hydration and had close monitoring of his urine output, creatinine, and CPK levels. His hospital course was uneventful without the development of acute renal failure and he was discharged after 14 days in hospital, with a CPK level of 2463 U/L. This case highlights that severe rhabdomyolysis may occur in patients with dengue fever and that early and aggressive treatment may prevent severe complications such as acute renal failure and death.

2019 ◽  
Vol 09 (03) ◽  
pp. 253-272
Author(s):  
Engoba Moyen ◽  
Verlem Bomelefa-Bomel ◽  
Gaston Ekouya-Bowassa ◽  
Tony Eyeni Sinomono ◽  
Aymar Pierre Gildas Oko ◽  
...  

2020 ◽  
Vol 66 (5) ◽  
pp. 504-510
Author(s):  
Kamolwish Laoprasopwattana ◽  
Wannee Limpitikul ◽  
Alan Geater

Abstract Background and aims After the 2009–11 outbreak of typhoid and chikungunya (CHIK) in Thailand, an effort was made to use complete blood counts and clinical profiles to differentiate these diseases to facilitate earlier specific treatment. Methods Patients aged 2–15 years having fever on first visit ≤3 days without localizing signs were enrolled retrospectively. Typhoid fever was confirmed by hemoculture, dengue by nonstructural protein-1 or polymerase chain reaction (PCR), and CHIK by PCR. Febrile children with negative results for these infections were classified as other acute febrile illness (AFI). Results Of the 264 cases, 56, 164, 25 and 19 had typhoid fever, dengue viral infection (DVI), CHIK and other AFI, respectively. Arthralgia had sensitivity, specificity, positive predictive value (PPV) and negative predictive value of 0.96, 0.97, 0.80 and 0.99, respectively, to differentiate CHIK from the others. After excluding CHIK by arthralgia, the PPV of the WHO 1997 and 2009 criteria for DVI increased from 0.65 and 0.73 to 0.95 and 0.84, respectively. Children with one of myalgia, headache or leukopenia had sensitivity of 0.84, specificity of 0.76 and PPV of 0.92 to differentiate DVI from typhoid and other AFIs. Patients with one of abdominal pain, diarrhea or body temperature >39.5°C were more likely to have typhoid fever than another AFI with PPV of 0.90. Conclusion Using this flow chart can help direct physicians to perform more specific tests to confirm the diagnosis and provide more specific treatment. Nevertheless, clinical follow-up is the most important tool in unknown causes of febrile illness.


Nephron ◽  
1999 ◽  
Vol 83 (2) ◽  
pp. 183-183 ◽  
Author(s):  
Didier Hommel ◽  
Antoine Talarmin ◽  
Jean-Marc Reynes ◽  
Alain Hulin

2017 ◽  
Vol 40 (5) ◽  
pp. 219-223 ◽  
Author(s):  
Andon Chibishev ◽  
Lidija Petkovska ◽  
Liljana Tozija ◽  
Milka Zdravkovska ◽  
Emilija Shikole

Introduction The aim of this study is to show the importance of hemodialysis as an active method in treatment of acute acetic acid poisonings. Its main role is to support the renal function during the state of the intoxication when patients develop acute renal failure. Methods We analyzed data from a 10-year period, a total of 71 patients who ingested acetic acid, either intentionally or accidentally. Patients with a need of hemodialysis (HD) treatment underwent 3- to 4-hour HD sessions every day or every second day, according to clinical assessment, as needed, until recovery of kidney function. Results In the period between 2006 and 2015 at the university clinic for toxicology and urgent internal medicine, we hospitalized 6,106 patients with different kinds of intoxication, of which 1.162% ingested concentrated acetic acid; 47 patients were female and 24 were male. The minimal age of patients was 18 and the maximal 74 years. A total of 28 (39.43%) of the patients developed acute renal failure and in 10 patients (14.08%) we used hemodialysis as a part of the treatment. The maximum number of performed sessions in one patient was five and the minimal number of performed sessions in one patents was only one session. The use of heparin led to fatal bleeding in 4 patients. The mortality rate was 7% and most of the cases resulted in fatalities during the first 96 hours after ingestion. Conclusions Acetic acid poisonings are one of the most dangerous intoxications seen in clinical toxicology. The use of hemodialysis in some of the patients who develop acute renal failure can be of great importance and it should be put into official treatment protocols due to its great number of advantages in renal function support.


2005 ◽  
Vol 13 (3) ◽  
pp. 142-143 ◽  
Author(s):  
Vinuchandran Ramachandran Nair ◽  
Dilip Unnikrishnan ◽  
B. Satish ◽  
M.I. Sahadulla

2020 ◽  
Vol 10 (01) ◽  
pp. 41-48
Author(s):  
Magara Samaké ◽  
Seydou Sy ◽  
Hamadoun Yattara ◽  
Moctar Coulibaly ◽  
Mamadou Badou Sanogo ◽  
...  

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