scholarly journals Correlation between Behavioural and Psychological Symptoms of Alzheimer Type Dementia and Plasma Homocysteine Concentration

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Zhanjie Zheng ◽  
Jindong Wang ◽  
Lei Yi ◽  
Hui Yu ◽  
Lingli Kong ◽  
...  
Keyword(s):  
Psychological Symptoms ◽  
Plasma Homocysteine ◽  
Healthy Controls ◽  
Alzheimer Type ◽  
Homocysteine Concentration ◽  
Alzheimer Type Dementia ◽  
Plasma Homocysteine Concentration ◽  
First Time ◽  
The Relationship ◽  
Behavioral And Psychological Symptoms

The relationship between plasma homocysteine and behavioral and psychological symptoms of dementia (BPSD) has not been specifically investigated in previous research. In this study, we compared plasma homocysteine (Hcy) among 40 Alzheimer’s disease (AD) patients with BPSD, 37 AD patients without BPSD, and 39 healthy controls. Our results evidenced that the plasma homocysteine levels in AD patients with BPSD and without BPSD were higher than healthy controls and that the plasma homocysteine concentration in AD patients with BPSD was the highest among the three groups. Significant correlation between plasma homocysteine concentration and cognitive decline and duration of dementia was observed, but there was no correlation between BPSD and cognitive dysfunction or duration of dementia. In conclusion, this study showed for the first time that BPSD were associated with plasma homocysteine concentration in Alzheimer's dementia, and the results supported that hyperhomocysteine may take part in the pathogenesis of BPSD.

Effect of 4-Week Treatment with Oral N-Acetylcysteine on Plasma Homocysteine Concentration and Antioxidant Activity of Patients on Chronic Hemodialysis

Kidney ◽  
2008 ◽  
Vol 17 (3) ◽  
pp. 122-125 ◽  
Author(s):  
Simin Dashti-Khavidaki ◽  
Hossein Khalili ◽  
Elmira Barzegar ◽  
Mahboob Lessan-Pezeshki ◽  
Mohammad Reza Khoshayand ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Plasma Homocysteine ◽  
Chronic Hemodialysis ◽  
Homocysteine Concentration ◽  
Plasma Homocysteine Concentration

scholarly journals Plasma Homocysteine Concentration in Acute Coronary Syndromes

2020 ◽  
Vol 12 (18) ◽  
pp. 14-19
Author(s):  
A. T. Pardesi ◽  
Dilip P. Patil ◽  
Nitin B. Jadav ◽  
Pramod Kulkarni ◽  
Dany John
Keyword(s):  
Acute Coronary Syndromes ◽  
Plasma Homocysteine ◽  
Homocysteine Concentration ◽  
Plasma Homocysteine Concentration ◽  
Coronary Syndromes

scholarly journals Association Between Plasma Homocysteine Concentration and Carotid Atherosclerosis in Hemodialysis Patients

1999 ◽  
Vol 63 (9) ◽  
pp. 692-696 ◽  
Author(s):  
Tai Sakurabayashi ◽  
Makoto Fujimoto ◽  
Yoshiji Takaesu ◽  
Susumu Haginoshita ◽  
Shin Goto ◽  
...  
Keyword(s):  
Carotid Atherosclerosis ◽  
Hemodialysis Patients ◽  
Plasma Homocysteine ◽  
Homocysteine Concentration ◽  
Plasma Homocysteine Concentration

scholarly journals Caregiver distress associated with behavioral and psychological symptoms in mild Alzheimer's disease

2010 ◽  
Vol 4 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Ari Pedro Balieiro Jr. ◽  
Emmanuelle Silva Tavares Sobreira ◽  
Marina Ceres Silva Pena ◽  
José Humberto Silva-Filho ◽  
Francisco de Assis Carvalho do Vale
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Psychological Symptoms ◽  
Time Behavior ◽  
Caregiver Distress ◽  
Night Time ◽  
The Mean ◽  
The Individual ◽  
The Relationship ◽  
Behavioral And Psychological Symptoms

Abstract The aim of this study was to analyze the relationship between Caregiver Distress and Behavioral and Psychological Symptoms in Dementias (BPSD) in mild Alzheimer's disease. Methods: Fifty patients and caregivers were interviewed using the Neuropsychiatric Inventory (NPI). Results: 96.0% of the patients had at least one BPSD. The mean NPI total score was 19.6 (SD=18.05; range=0-78) whereas the mean Caregiver Distress Index (CDI) total score was 11.5 (SD=10.41; range=0-40). For the individual symptoms, the weighted mean CDI was 2.8 (SD=1.58). All symptom CDI means were higher than 2.0 except for euphoria/elation (m=1.8; SD=1.49). There were correlations between CDI and derived measures (Frequency, Severity, FxS, and Amplitude) for all symptoms, except Disinhibition and Night-time behavior. Correlations ranged between 0.443 and 0.894, with significance at p<0.05. Conclusions: All the derived measures, including amplitude, were useful in at least some cases. The data suggests that CDI cannot be inferred from symptom presence or profile. Symptoms should be systematically investigated.

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