scholarly journals Random Whole Body Vibration over 5 Weeks Leads to Effects Similar to Placebo: A Controlled Study in Parkinson’s Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Heiko Gaßner ◽  
Annette Janzen ◽  
Ansgar Schwirtz ◽  
Petra Jansen

Background. Random whole body vibration (WBV) training leads to beneficial short-term effects in patients with Parkinson’s disease (PD). However, the effect of WBV lasting several weeks is not clear.Objectives. The aim of this study was to assess a random WBV training over 5 weeks in PD.Methods.Twenty-one participants with PD were allocated to either an experimental or a placebo group matched by age, gender, and Hoehn&Yahr stage. The WBV training consisted of 5 series, 60 s each. In the placebo group, vibration was simulated. The primary outcome was the change of performance in Functional reach test (FRT), step-walk-turn task, biomechanical Gait Analysis, Timed up and go test (TUG), and one leg stance.Findings. In most of the parameters, there was no significant interaction of “time*group.” Both groups improved significantly in Gait parameters, TUG, and one leg stance. Only in the FRT [F(1,15)=8.397;P<0.05] and in the TUG [F(1,15)=4.971;P<0.05] the experimental group performed significantly better than the placebo group.Conclusions. Random WBV training over 5 weeks seems to be less effective than reported in previous studies performing short-term training. The slight improvements in the FRT and TUG are not clinically relevant.

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Oliver Kaut ◽  
Daniel Brenig ◽  
Milena Marek ◽  
Niels Allert ◽  
Ullrich Wüllner

Background.Postural instability in Parkinson’s disease (PD) increases the risk of falls and is not improved by pharmacological therapy.Objective.We performed a double-blind, randomized sham-controlled study to test the effects of stochastic resonance (whole body vibration) therapy on postural stability in PD.Methods.Fifty-six PD participants were allocated to either experimental or sham groups. The experimental group received four series of vibration over eight days, with each series consisting of six stimulus trains of 60-second duration using a randomized whole body vibration. Participants allocated to the control group received a sham treatment.Results.Within-group analysis revealed that postural stability in the experimental group improved by 17.5% (p=0.005) comparing experimental and sham groups. The between-group analysis of change after treatment comparing both groups also showed a significant improvement of postural stability (p=0.03). Only in the within-group analysis several items were improved after Bonferroni correction, too, rigor 41.6% (p=0.001), bradykinesia 23.7% (p=0.001), tremor 30.8% (p=0.006), andUPDRSIIIsum score 23.9% (p=0.000), but did not reach the level of significance in the between-group analysis.Conclusions.Stochastic resonance therapy significantly enhanced postural stability even in individuals with increased risk of falling. Thus it offers a potential supplementation to canonical treatments of PD.


2009 ◽  
Vol 24 (6) ◽  
pp. 891-898 ◽  
Author(s):  
Pablo Arias ◽  
Marcelo Chouza ◽  
Jamile Vivas ◽  
Javier Cudeiro

Author(s):  
Eduardo Guadarrama-Molina ◽  
Carlos Enrique Barrón-Gámez ◽  
Ingrid Estrada-Bellmann ◽  
Jesús D. Meléndez-Flores ◽  
Paola Ramírez-Castañeda ◽  
...  

2020 ◽  
pp. 1-12
Author(s):  
Chuan He ◽  
Caixia Su ◽  
Wentong Zhang ◽  
Qi Wan

Abstract Objective: To review the effects of whole body vibration for patients with Parkinson’s disease. Design: Randomized clinical trials comparing whole body vibration with no vibration or conventional physical therapy for patients with Parkinson’s disease were searched up to July 31, 2019. Results: Seven studies with 196 patients were included for quantitative analysis. No significant difference was found between groups in motor score of unified Parkinson’s disease rating scale (UPDRS-III) (WMD [weighted mean difference] = −1.75, 95% CI, −5.40 to 1.90, I2 = 45.8%), functional reach test (SMD [standardized mean difference] = 0.21, 95% CI, −0.29 to 0.71; I2 = 0%), and other balance tests (including Berg balance test and Tinetti score) (SMD = 0.39, 95% CI, −0.01 to 0.80; I2 = 0%). No statistical difference was detected in walking velocity as well (WMD = −0.05, 95% CI, −0.17 to 0.06; I2 = 0%). In contrast, the pooled analysis from four studies on the Time Up and Go test showed favorable results for whole body vibration (WMD = −1.59, 95% CI, −2.90 to −0.28, I2 = 0%). Conclusion: Whole body vibration may not be beneficial over placebo or conventional physical therapy in overall motor function, balance, and walking velocity in patients with Parkinson’s disease. However, it might have positive effects on sit to stand transitions or turning.


2018 ◽  
Vol 39 (12) ◽  
pp. 2159-2168 ◽  
Author(s):  
Silvia Corbianco ◽  
Gabriella Cavallini ◽  
Giacomo Baldereschi ◽  
Maria Chiara Carboncini ◽  
Francesca Lidia Fiamingo ◽  
...  

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