scholarly journals Ramsay Hunt Syndrome in a Patient with Rheumatoid Arthritis after Treatment with Infliximab

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Yoshio Nagayama ◽  
Naoki Matsushiro ◽  
Akihide Nampei ◽  
Hideo Hashimoto ◽  
Kenrin Shi
Keyword(s):  
Rheumatoid Arthritis ◽  
Adverse Effect ◽  
Virus Infection ◽  
Complete Recovery ◽  
Varicella Zoster Virus Infection ◽  
Geniculate Ganglion ◽  
Infliximab Treatment ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome

A 39-year-old female patient with rheumatoid arthritis developed Ramsay Hunt syndrome after infliximab treatment. This condition is caused by the reactivation of varicella zoster virus infection in the geniculate ganglion of facial nerve in the host’s immunosuppression. She was treated immediately with valaciclovir and hydrocortisone, and the complete recovery was achieved at 6 months after the onset. This is the first report of Ramsay Hunt syndrome as an adverse effect of infliximab in rheumatoid arthritis.

scholarly journals Ramsay Hunt Syndrome Complicated by Brainstem Encephalitis in Varicella-zoster Virus Infection

2015 ◽  
Vol 128 (23) ◽  
pp. 3258-3259 ◽  
Author(s):  
Yao-Yao Shen ◽  
Ting-Min Dai ◽  
Hai-Ling Liu ◽  
Wei Wu ◽  
Jiang-Long Tu
Keyword(s):  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Varicella Zoster Virus Infection ◽  
Brainstem Encephalitis ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome

scholarly journals Ramsay hunt syndrome- expect the unexpected: A case report

2021 ◽  
Vol 7 (3) ◽  
pp. 172-175
Author(s):  
Poorva Saxena ◽  
G. V. Ramachandra Reddy ◽  
Hina Handa ◽  
Ajita Singh
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Neurological Diseases ◽  
Rare Complication ◽  
Varicella Zoster Virus Infection ◽  
Post Herpetic Neuralgia ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Vesicular Rash

Herpes zoster represents a latent reactivation of the varicella zoster virus infection with a dermatomal pattern of eruption and complicated by post-herpetic neuralgia. Ramsay hunt syndrome is a rare complication of herpes zoster and it is not just a syndrome but it's rather an infectious disease. This syndrome is characterized by peripheral facial nerve palsy associated with an erythematous vesicular rash on the ear. It is characterized by unilateral pattern of facial involvement and presence of vesicles helps in early diagnosis and distinguish the syndrome with diseases mimicking other severe neurological diseases. This article reports a case of 56-year-old male patient who reported with a complaint of severe toothache, which serves as severe prodrome for reactivation of herpes zoster virus which later leads to Ramsay Hunt syndrome. This case report highlights about the management of herpes zoster and its complication and emphasizes on prevention of post herpetic neuralgia complication.

scholarly journals Facial paralysis due to Ramsay Hunt syndrome - A rare condition

2017 ◽  
Vol 63 (4) ◽  
pp. 301-302 ◽  
Author(s):  
Aline Lariessy Campos Paiva ◽  
João Luiz Vitorino Araujo ◽  
Vinicius Ricieri Ferraz ◽  
José Carlos Esteves Veiga
Keyword(s):  
Herpes Zoster ◽  
Facial Paralysis ◽  
Rare Complication ◽  
Rare Condition ◽  
Varicella Zoster Virus Infection ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Condition Diagnosis ◽  
Symptoms And Signs

Summary Ramsay Hunt syndrome (or herpes zoster oticus) is a rare complication of herpes zoster in which reactivation of latent varicella zoster virus infection in the geniculate ganglion occurs. Usually, there are auricular vesicles and symptoms and signs such otalgia and peripheral facial paralysis. In addition, rarely, a rash around the mouth can be seen. Immunodeficient patients are more susceptible to this condition. Diagnosis is essentially based on symptoms. We report the case of a diabetic female patient who sought the emergency department with a complaint of this rare entity.

A CASE OF MRI-NEGATIVE HERPES VIRUS ENCEPHALITIS PRESENTED BY RAMSAY HUNT SYNDROME

2020 ◽  
Vol 73 (11) ◽  
pp. 2555-2556
Author(s):  
Pavel A. Dyachenko ◽  
Anatoly G. Dyachenko
Keyword(s):  
Clinical Symptoms ◽  
Clinical Findings ◽  
Brain Parenchyma ◽  
Geniculate Ganglion ◽  
Cranial Nerve Involvement ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
The Brain ◽  
Multiple Cranial Nerve

Ramsay Hunt syndrome (RHS) occurs due to reactivation of latent Varicella Zoster Virus (VZV) infection in the geniculate ganglion of the facial nerve. Major clinical symptoms include ipsilateral facial paralysis, otic pain, and herpetic vesicles (rashes) along the nerve with accompanying ear pain. Rarely clinical findings include retrograde transaxonal spread of the virus from the ganglion into the brain parenchyma with developing the encephalitis or multiple cranial nerve involvement. We describe here a patient with both RHS along with complicating brains

Tofacitinib-induced Ramsay- Hunt Syndrome in a Patient with Rheumatoid Arthritis

2020 ◽  
Vol 15 ◽  
Author(s):  
Senol Kobak
Keyword(s):  
Rheumatoid Arthritis ◽  
Hearing Loss ◽  
Facial Nerve ◽  
Varicella Zoster Virus ◽  
Facial Nerve Paralysis ◽  
Nerve Paralysis ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Intravenous Acyclovir

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint and systemic involvement. Tofacitinib is a JAK- inhibitor that is an effective agent in the treatment of active RA. Varicella zoster virus (VZV) reactivation is among the most important advers effects of tofacitinib. Ramsay-Hunt syndrome (RHS) is a rare clinical condition that develop as a result of VZV reactivation and progresses with hearing loss, dizziness and facial nerve paralysis. Objective: To present a case with Ramsay-Hunt syndrome due to varicella zoster reactivation in RA patient using tofacitinib Case report: A 63-year-old female RA patient under tofacitinib treatment was admitted to the rheumatology outpatient clinic due to widespread skin rashes on her face and ear, and hearing loss. On inspection widespread erythematous, vesicular rashes on the left side of the face, lips, around the eye and in the ear, and mild facial paralysis on the left side were detected. On laboratory investigations acute phase reactants were increased. Serological study for specific antibodies against varicella zoster virus showed higher titers. Dermatology and ear nose throat specialist consultations was performed, varicella zoster lesions on the left inner ear, face and mild facial paresis were considered. According to clinical and laboratory findings the patient was diagnosed with RHS triggered by tofacitinib. Tofacitinib and methotrexate was discontinued, and intravenous acyclovir was started. On the control examination the patient's skin lesions and facial nerve paralysis regressed. Conclusion: Herein we reported the fırst case of tofacitinib-induced RHS in a patient with RA. This is may be the another side effect of biologic treatment. New studies are needed in this subject.

scholarly journals Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Vijay Letchuman ◽  
Charles D. Donohoe
Keyword(s):  
Varicella Zoster Virus ◽  
Facial Paralysis ◽  
Cerebral Peduncle ◽  
Geniculate Ganglion ◽  
Abducens Nucleus ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Intravenous Acyclovir ◽  
Clinical Awareness

We present a case of a 62-year-old Caucasian male with laryngeal cancer and Ramsay Hunt Syndrome otherwise known as herpes zoster oticus due to reactivation of the varicella zoster virus. Classic findings include the triad of ipsilateral facial paralysis, otic pain, and herpetic lesions in the sensory supply of the facial nerve. The common pathogenesis is associated with anterograde axonal reactivation of the varicella zoster virus in the geniculate ganglion. Unique features of our case include retrograde transaxonal spread of the varicella-zoster virus from the geniculate ganglion into the brainstem and cerebellum including involvement of the abducens nucleus, facial nucleus, middle cerebral peduncle, and inferior cerebellar peduncle. This presented as left facial paralysis, left sixth nerve palsy, horizontal diplopia to the left lateral gaze, profound truncal ataxia, and left-sided dysmetria. Clinical awareness that Ramsay Hunt syndrome may also involve the brainstem and cerebellum is critical in evaluating the clinical neurologic findings and expanding the diagnostic workup to include brain magnetic resonance imaging and cerebrospinal fluid analysis, including varicella zoster polymerase chain reaction. Encephalitis requires longer duration administration of high-dose intravenous acyclovir in conjunction with steroids. Delays in treatment are often associated with unsatisfactory outcomes with extensive residual deficits.

scholarly journals A Pediatric Case of Ramsay Hunt Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Serhan Derin ◽  
Hatice Derin ◽  
Murat Sahan ◽  
Hüseyin Çaksen
Keyword(s):  
Facial Nerve ◽  
Facial Paralysis ◽  
Rare Case ◽  
Geniculate Ganglion ◽  
Peripheral Facial Paralysis ◽  
Pediatric Case ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Inner Ear Dysfunction

Ramsay Hunt syndrome (RHS) is characterized by facial paralysis, inner ear dysfunction, periauricular pain, and herpetiform vesicles. The reported incidence in children is 2.7/100,000. The pathogenesis involves the reactivation of latent varicella zoster virus (VZV) in the geniculate ganglion of the facial nerve. The recovery rate is better in children than in adults. This paper discusses a 12-year-old girl with a rare case of peripheral facial paralysis caused by RHS and reviews the literature.

scholarly journals Ramsay hunt syndrome- expect the unexpected: A case report

2021 ◽  
Vol 7 (3) ◽  
pp. 172-175
Author(s):  
Poorva Saxena ◽  
G. V. Ramachandra Reddy ◽  
Hina Handa ◽  
Ajita Singh
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Neurological Diseases ◽  
Rare Complication ◽  
Varicella Zoster Virus Infection ◽  
Post Herpetic Neuralgia ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
Vesicular Rash

Herpes zoster represents a latent reactivation of the varicella zoster virus infection with a dermatomal pattern of eruption and complicated by post-herpetic neuralgia. Ramsay hunt syndrome is a rare complication of herpes zoster and it is not just a syndrome but it's rather an infectious disease. This syndrome is characterized by peripheral facial nerve palsy associated with an erythematous vesicular rash on the ear. It is characterized by unilateral pattern of facial involvement and presence of vesicles helps in early diagnosis and distinguish the syndrome with diseases mimicking other severe neurological diseases. This article reports a case of 56-year-old male patient who reported with a complaint of severe toothache, which serves as severe prodrome for reactivation of herpes zoster virus which later leads to Ramsay Hunt syndrome. This case report highlights about the management of herpes zoster and its complication and emphasizes on prevention of post herpetic neuralgia complication.

scholarly journals Ramsay Hunt syndrome presenting as simple otitis externa

CJEM ◽  
2008 ◽  
Vol 10 (03) ◽  
pp. 247-250 ◽  
Author(s):  
Daniel Kim ◽  
Munsif Bhimani
Keyword(s):  
Otitis Externa ◽  
Clinical Presentation ◽  
Rare Complication ◽  
Varicella Zoster Virus Infection ◽  
Facial Weakness ◽  
Peripheral Facial Paralysis ◽  
Varicella Zoster ◽  
Ramsay Hunt Syndrome ◽  
Hunt Syndrome ◽  
History Of

ABSTRACTRamsay Hunt syndrome is a rare complication of herpes zoster in which reactivation of latent varicella zoster virus infection occurs in the geniculate ganglion, causing otalgia, auricular vesicles and peripheral facial paralysis. Because these symptoms do not always present at the onset, this syndrome can be misdiagnosed. We report the case of a patient who was diagnosed with simple otitis externa after presenting to the emergency department (ED) with a 3-day history of right-sided otalgia. Her condition subsequently evolved to include right-sided auricular vesicles and right-sided facial weakness. She presented to the ED again after 2 days and was correctly diagnosed with Ramsay Hunt syndrome. We describe the clinical presentation, diagnostic findings and management of this uncommon but important entity.

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