Somatosensory and Brainstem Auditory Evoked Potentials Assessed between 4 and 7 Days after Severe Stroke Onset Predict Unfavorable Outcome

Our objective was to explore the best predictive timing of short-latency somatosensory evoked potentials (SLSEP) and brainstem auditory evoked potentials (BAEP) for unfavorable outcomes in patients with early stage severe stroke. One hundred fifty-six patients with acute severe supratentorial stroke were monitored according to SLSEP, BAEP, and the Glasgow Coma Scale (GCS) at 1–3 days and 4–7 days after the onset of stroke. All patients were followed up for outcomes at 6 months after onset using the modified Rankin Scale (mRS), with a score of 5-6 considered unfavorable. The predictive values of SLSEP, BAEP, and the GCS at 1–3 days were compared with 4–7 days after onset. Our results show that, according to the analysis of prognostic authenticity, the predictive values of SLSEP and BAEP at 4–7 days after stroke onset improved when compared with the values at 1–3 days for unfavorable outcomes. Most of the patients with change of worsening evoked potentials from 1–3 days to 4–7 days after onset had unfavorable outcomes. In conclusion, SLSEP and BAEP assessed at 4–7 days after onset predicted unfavorable outcomes for acute severe stroke patients. The worsening values of SLSEP and BAEP between 1–3 days and 4–7 days also present a prognostic value.

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Prognostic value of brainstem auditory evoked potentials in pediatric patients with traumatic coma

Resuscitation ◽

10.1016/0300-9572(88)90077-9 ◽

1988 ◽

Vol 16 (2) ◽

pp. 127-131 ◽

Cited By ~ 2

Author(s):

S. Nataloni ◽

M. Gentili ◽

R. Pagni ◽

M. Valente ◽

S. Gentili ◽

...

Keyword(s):

Evoked Potentials ◽

Prognostic Value ◽

Auditory Evoked Potentials ◽

Pediatric Patients ◽

Brainstem Auditory Evoked Potentials ◽

Traumatic Coma

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Predictive values of maximum changes of brainstem auditory evoked potentials during microvascular decompression for hemifacial spasm

Acta Neurochirurgica ◽

10.1007/s00701-020-04379-6 ◽

2020 ◽

Vol 162 (11) ◽

pp. 2823-2832

Author(s):

Yulian Zhang ◽

Hongxiang Ren ◽

Ge Jia ◽

Li Zhang ◽

Guohui Fan ◽

...

Keyword(s):

Evoked Potentials ◽

Hemifacial Spasm ◽

Microvascular Decompression ◽

Auditory Evoked Potentials ◽

Brainstem Auditory Evoked Potentials ◽

Predictive Values

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Search for clinical and neurophysiological prognostic patterns of brain coma outcomes in children

Medicina ◽

10.3390/medicina44040035 ◽

2008 ◽

Vol 44 (4) ◽

pp. 273 ◽

Cited By ~ 3

Author(s):

Rūta Liesienė ◽

Rimantas Kėvalas ◽

Ingrida Ulozienė ◽

Eglė Gradauskienė

Keyword(s):

Glasgow Coma Scale ◽

Evoked Potentials ◽

Computerized Tomography ◽

Auditory Evoked Potentials ◽

Treatment Protocol ◽

Pediatric Intensive Care ◽

Lung Ventilation ◽

Brainstem Auditory Evoked Potentials ◽

Predictive Values ◽

Coma Scale

Objective. The aim of the study was to evaluate the possible predictive values of clinical examinations combined with the recordings of electroencephalography and brainstem auditory-evoked potentials in traumatic coma of pediatric patients. Material and methods. A total of 43 children in coma with severe acute head trauma were included in the study. They were investigated and treated in pediatric intensive care unit using standard evaluation and treatment protocol. Evaluation of coma was performed using Glasgow Coma Scale. Electroencephalography for 35 patients and brainstem auditory-evoked potentials for 24 patients were recorded. Results. Glasgow coma scale statistic pool median was equal to 4 points as measured in presence of brain edema, meanwhile it was 6 as measured in absence of edema. In case of supratentorial damage, median duration of consciousness recovery was 10 days. In absence of above-mentioned supratentorial damage, recovery of the consciousness was earlier – median was 5 days. Determined duration of artificial lung ventilation was statistically significantly shorter for those who had edema (P=0.048). In 20 patients (57% of all cases), constant or alternating slow wave activity was observed during the first electroencephalographic recording. In other cases, “alpha coma” or low amplitude of arrhythmic activity and local slowing activity corresponding to brain damage seen on computerized tomography were recorded. For 24 patients, brainstem auditory-evoked potentials were recorded. In 9 cases, they were abnormal; in these cases, the consciousness of the patients recovered after 44 days or did not recover. Conclusions. Glasgow coma scale results alone may have limited prognostic value in absence of other objective neurophysiologic investigation data concerning the coma outcome in children. Prognosis may be worse if pathological brainstem auditory-evoked potentials correlate with pathological dynamic changes in electroencephalography and brain lesions, diagnosed during computerized tomography scan.

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