scholarly journals Hyperchloremic Metabolic Acidosis due to Cholestyramine: A Case Report and Literature Review

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Fareed B. Kamar ◽  
Rory F. McQuillan
Keyword(s):  
Acute Kidney Injury ◽  
Renal Failure ◽  
Case Report ◽  
Metabolic Acidosis ◽  
Bile Acid ◽  
Literature Review ◽  
Adult Male ◽  
Kidney Injury ◽  
Bile Acid Malabsorption ◽  
Hyperchloremic Metabolic Acidosis

Cholestyramine is a bile acid sequestrant that has been used in the treatment of hypercholesterolemia, pruritus due to elevated bile acid levels, and diarrhea due to bile acid malabsorption. This medication can rarely cause hyperchloremic nonanion gap metabolic acidosis, a complication featured in this report of an adult male with concomitant acute kidney injury. This case emphasizes the caution that must be taken in prescribing cholestyramine to patients who may also be volume depleted, in renal failure, or taking spironolactone.

scholarly journals Venom Induced Toxic Ventriculitis Resulting in Acute Reversible Communicating Internal Hydrocephalus, Acute Pituitary Haemorrhage, Acute Hypopituitarism, Acute Kidney Injury, Septicaemia, Cellulitis and DIC Due to Viper Bite in a Young Farmer: A Case Report

2021 ◽  
Vol 2 (8) ◽  
pp. 654-659
Author(s):  
Khin Phyu Pyar ◽  
Soe Win Hlaing ◽  
Aung Aung ◽  
Zar Ni Htet Aung ◽  
Nyan Lin Maung ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Failure ◽  
Cerebrospinal Fluid ◽  
Case Report ◽  
Renal Replacement Therapy ◽  
Ct Scan ◽  
Kidney Injury ◽  
Free T4 ◽  
Enhanced Ct ◽  
Internal Hydrocephalus

A young farmer, tenth standard student, helping his grandfather during holiday, developed anuria after viper bite. Because of headache, non-enhanced CT scan head was done on admission which showed a small pituitary haemorrhage with normal ventricles. Later, he had generalized fits and second non-enhanced CT scan head was repeated which revealed a small pituitary haemorrhage with dilated ventricles. He also had acute kidney injury, septicaemia, cellulitis and DIC. The serum level of TSH, free T3 & free T4 were low; thus, replacement was done. Cerebrospinal fluid study (protein, sugar, cells) including culture was normal. Renal replacement therapy (haemodialysis), platelets transfusion and antibiotics were given. He had torrential polyuria (urine output 12 liter per day) when he recovered from renal failure and it improved dramatically with desmopressin replacement. There was improvement in third non-enhanced CT scan head and fourth one was consistent with normal ventricle and reduction in size of pituitary haemorrhage.

scholarly journals Zhenju Jiangya Tablet-induced Acute Kidney Injury: A Case Report and Literature Review

2016 ◽  
Author(s):  
B Li ◽  
Q Wen ◽  
Z Gao ◽  
Z Hu ◽  
X Yang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Case Report ◽  
Literature Review ◽  
Kidney Injury

scholarly journals Rifampicin-induced Acute Kidney Injury During the Initial Treatment for Pulmonary Tuberculosis: A Case Report and Literature Review

2013 ◽  
Vol 52 (21) ◽  
pp. 2457-2460 ◽  
Author(s):  
Sahoko Chiba ◽  
Kimitake Tsuchiya ◽  
Hiroyuki Sakashita ◽  
Eisaku Ito ◽  
Naohiko Inase
Keyword(s):  
Acute Kidney Injury ◽  
Case Report ◽  
Literature Review ◽  
Pulmonary Tuberculosis ◽  
Initial Treatment ◽  
Kidney Injury

scholarly journals Ethylene Glycol Intoxication Requiring ECMO Support

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Raphael Rosen ◽  
Shelief Robbins-Juarez ◽  
Jacob Stevens
Keyword(s):  
Acute Kidney Injury ◽  
Renal Failure ◽  
Metabolic Acidosis ◽  
Ethylene Glycol ◽  
Extracorporeal Membrane Oxygenation ◽  
Kidney Injury ◽  
Neurological Injury ◽  
Severe Metabolic Acidosis ◽  
Toxic Metabolites ◽  
Ethylene Glycol Intoxication

Ethylene glycol is commonly used in antifreeze, and ingestion of even a small amount can result in acute kidney injury, severe metabolic acidosis, and neurological injury. When cases are recognized early, treatment involves administration of alcohol dehydrogenase inhibitors to prevent conversion to toxic metabolites of glycolate, glyoxolate, and oxalate. In later presentations with more severe renal injury, hemodialysis may be required for clearance of toxic metabolites and supportive care for renal failure. We present the first reported case of severe ethylene glycol intoxication requiring support of extracorporeal membrane oxygenation (ECMO) due to refractory cardiopulmonary collapse.

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