Cocaine and Alcohol Co-Ingestion-Induced Severe Rhabdomyolysis With Acute Kidney Injury Culminating in Hemodialysis-Dependent End-Stage Renal Disease: A Case Report and Literature Review

AbstractCurrent acute kidney injury (AKI) diagnostic criteria are restricted to the inpatient setting. We proposed a new AKI diagnostic algorithm for the outpatient setting and evaluate whether outpatient AKI (AKIOPT) modifies the disease course among patients with chronic kidney disease (CKD) enrolled in the national predialysis registry. AKIOPT was detected when a 50% increase in serum creatinine level or 35% decline in eGFR was observed in the 180-day period prior to enrollment in the predialysis care program. Outcomes were progression to end-stage renal disease (ESRD) and all-cause mortality. Association analyses were performed using multiple Cox regression and coarsened exact matching (CEM) analysis. Among 6,046 patients, 31.5% (1,905 patients) had developed AKIOPT within the 180-day period before enrollment. The adjusted hazard ratios of the 1-year and overall risk of ESRD among patients with preceding AKIOPT compared with those without AKIOPT were 2.61 (95% CI: 2.15–3.18) and 1.97 (1.72–2.26), respectively. For 1-year and overall risk of all-cause mortality, patients with AKIOPT had respectively a 141% (95% CI: 89–209%) and 84% (56–117%) higher risk than those without AKIOPT. This statistical inference remained robust in CEM analysis. We also discovered a complete reversal in the eGFR slope before and after the AKIOPT from −10.61 ± 0.32 to 0.25 ± 0.30 mL/min/1.73 m2 per year; however, the loss of kidney function is not recovered. The new AKIOPT diagnostic algorithm provides prognostic insight in patients with CKD.

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Early Postoperative Acute Kidney Injury and End Stage Renal Disease in Lung Transplant Recipients

10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2832 ◽

2020 ◽

Author(s):

M. Botros ◽

J. Kenneth ◽

P. Singh ◽

B. Keller

Keyword(s):

Acute Kidney Injury ◽

Renal Disease ◽

End Stage Renal Disease ◽

Lung Transplant ◽

Kidney Injury ◽

Transplant Recipients ◽

Lung Transplant Recipients ◽

Stage Renal Disease ◽

End Stage

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A Case of Immunotactoid Glomerulopathy with Rapid Progression to End-Stage Renal Disease

The Scientific World JOURNAL ◽

10.1100/tsw.2009.164 ◽

2009 ◽

Vol 9 ◽

pp. 1348-1354 ◽

Cited By ~ 2

Author(s):

Shikha Jain ◽

Darshika Chhabra

Keyword(s):

Acute Kidney Injury ◽

Renal Disease ◽

End Stage Renal Disease ◽

Kidney Injury ◽

Initial Presentation ◽

Rapid Progression ◽

First Case ◽

Immunotactoid Glomerulopathy ◽

Stage Renal Disease ◽

End Stage

Immunotactoid glomerulopathy (IGN) is a rare immunoglobulin deposition disease. It is often mistaken for cryoglobulinemia or amyloidosis due to the similarities on biopsy findings. The disease progresses to end-stage renal disease (ESRD) within 7 months to 10 years. This is the first case reported of a patient with a diagnosis of IGN who developed acute kidney injury (AKI) and ESRD within 1 week of initial presentation.

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Acute Kidney Injury After Surgical AVR and Long-Term Risk of Death and End-Stage Renal Disease

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2015.08.883 ◽

2015 ◽

Vol 66 (20) ◽

pp. 2263-2264 ◽

Cited By ~ 3

Author(s):

Linda C. Rydén ◽

Ulrik Sartipy ◽

Martin J. Holzmann

Keyword(s):

Acute Kidney Injury ◽

Renal Disease ◽

End Stage Renal Disease ◽

Kidney Injury ◽

Risk Of Death ◽

Stage Renal Disease ◽

End Stage

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Non‐Vitamin K Antagonist Oral Anticoagulants Provide Less Adverse Renal Outcomes Than Warfarin In Non‐Valvular Atrial Fibrillation: A Systematic Review and MetaAnalysis

Journal of the American Heart Association ◽

10.1161/jaha.120.019609 ◽

2021 ◽

Author(s):

Patita Sitticharoenchai ◽

Kullaya Takkavatakarn ◽

Smonporn Boonyaratavej ◽

Kearkiat Praditpornsilpa ◽

Somchai Eiam‐Ong ◽

...

Keyword(s):

Atrial Fibrillation ◽

Acute Kidney Injury ◽

Renal Disease ◽

End Stage Renal Disease ◽

Oral Anticoagulants ◽

Kidney Injury ◽

Incidence Rates ◽

Renal Outcomes ◽

Stage Renal Disease ◽

End Stage

Background Non‐vitamin K antagonist oral anticoagulants (NOACs) have better pharmacologic properties than warfarin and are recommended in preference to warfarin in most patients with non‐valvular atrial fibrillation. Besides lower bleeding complications, other advantages of NOACs over warfarin particularly renal outcomes remain inconclusive. Methods and Results Electronic searches were conducted through Medline, Scopus, Cochrane Library databases, and ClinicalTrial.gov. Randomized controlled trials and observational cohort studies reporting incidence rates and hazard ratio (HR) of renal outcomes (including acute kidney injury, worsening renal function, doubling serum creatinine, and end‐stage renal disease) were selected. The random‐effects model was used to calculate pooled incidence and HR with 95% CI. Eighteen studies were included. A total of 285 201 patients were enrolled, 118 863 patients with warfarin and 166 338 patients with NOACs. The NOACs group yielded lower incidence rates of all renal outcomes when compared with the warfarin group. Patients treated with NOACs showed significantly lower HR of risk of acute kidney injury (HR, 0.70, 95% CI, 0.64–0.76; P <0.001), worsening renal function (HR, 0.83; 95% CI, 0.73–0.95; P =0.006), doubling serum creatinine (HR, 0.58; 95% CI, 0.41–0.82; P =0.002), and end‐stage renal disease (HR, 0.82; 95% CI, 0.78–0.86; P <0.001). Conclusions In non‐valvular atrial fibrillation, patients treated with NOACs have a lower risk of both acute kidney injury and end‐stage renal disease when compared with warfarin.

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