scholarly journals Pneumatosis Cystoides Intestinalis after Cetuximab Chemotherapy for Squamous Cell Carcinoma of Parotid Gland

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Christos Petrides ◽  
Neofytou Kyriakos ◽  
Ioannou Andreas ◽  
Parpounas Konstantinos ◽  
Georgiou Chrysanthos ◽  
...  

Pneumatosis intestinalis, defined as gas in the bowel wall, is often first identified on abdominal radiographs or computed tomography (CT) scans. It is a radiographic finding and not a diagnosis, as the etiology varies from benign conditions to fulminant gastrointestinal disease. We report here a case of pneumatosis intestinalis associated with cetuximab therapy for squamous cell carcinoma of head and neck. The patient underwent laparotomy based on the CT scan and the result was pneumatosis intestinalis without any signs of necrotizing enterocolitis.

2006 ◽  
Vol 123 (4) ◽  
pp. 144-147
Author(s):  
M. Wiltgen ◽  
A. Holzinger ◽  
R. Groell ◽  
G. Wolf ◽  
W. Habermann

2021 ◽  
Vol 3 (3) ◽  
pp. e200131
Author(s):  
Derek Hsu ◽  
Tanya J. Rath ◽  
Barton F. Branstetter ◽  
Yoshimi Anzai ◽  
C. Douglas Phillips ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
pp. 29-36
Author(s):  
A.  A. Lyanova ◽  
L.  Yu. Vladimirova ◽  
E.  M. Frantsiyants ◽  
I.  V. Neskubina ◽  
M.  A. Engibaryan ◽  
...  

Objective. Studying the blood levels of type 1 and 2 insulin-like growth factors in patients with squamous cell carcinoma of the tongue and mouth floor mucosa depending on the therapy effect.Materials and Methods. The study included data from 30 patients with squamous cell carcinoma of the tongue and mouth floor mucosa T3–4N0–1M0 who received chemotherapy cycles together with targeted therapy with cetuximab. Twenty non-cancer donors were examined as well. Depending on the therapy effect, patients were divided into two groups: sensitive and resistant ones.Results. Initial levels of IGF-1 and IGF-2 in the blood serum of patients prior to chemotherapy and targeted therapy with cetuximab were lower than the levels in donors by 53.5 % and 20.3 %, respectively. After chemotherapy and cetuximab therapy, patients with sensitivity to the treatment showed normalization of IGF-1 and its significant increase compared to the initial levels — by 87 %. Levels of IGF-2 were not statistically significantly different from the initial levels and were 32.5 % lower than in donors. The IGF-1 / IGF-2 coefficient was 58 % higher than the initial value.Conclusions. Chemotherapy and cetuximab therapy normalized levels of IGF-1 in patients with sensitivity to the treatment which was demonstrated by an increase in IGF-1 up to the normal blood levels in effective treatment.


1988 ◽  
Vol 99 (5) ◽  
pp. 455-464 ◽  
Author(s):  
John H. Isaacs ◽  
Anthony A. Mancuso ◽  
William M. Mendenhall ◽  
James T. Parsons

In addition to clinical examination and less sophisticated radiographic techniques, high-resolution computerized tomography (CT) can help to stage squamous cell carcinoma of the larynx. This study was undertaken to identify findings on CT scans that might predict the likelihood of radiation therapy (RT) alone, controlling the primary site disease without significant irradiation-related complications. Of 30 patients with T2–4 cancers of the larynx, 13 were classified as favorable and 17 were classified as unfavorable candidates for RT based on the CT criteria of transglottic spread, more than 25% pre-epiglottic space involvement, extensive paralaryngeal space spread, or cartilage involvement. Seven of 17 (41%) unfavorable patients had local recurrences, two are alive with cancer, three patients are dead of disease (DOD), and five had significant complication, but there was no evidence of recurrent cancer. In the favorable group, there were two local recurrences (15%), one distant metastasis, one patient is DOD, and one had a significant complication, but no recurrent cancer. These data may be used to more adequately select and inform patients with T2–4 squamous cell carcinoma of the larynx before RT.


2011 ◽  
Vol 144 (5) ◽  
pp. 676-684 ◽  
Author(s):  
Travis D. Reeves ◽  
Elizabeth G. Hill ◽  
Kent E. Armeson ◽  
M. Boyd Gillespie

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