scholarly journals Primary Splenic Angiosarcoma Presenting as Idiopathic Thrombocytopenic Purpura: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
S. Christopher N. Frontario ◽  
Anna Goldenberg-Sandau ◽  
Darshan Roy ◽  
Roy Sandau

Angiosarcoma of the spleen is a rare malignancy that arises from vascular endothelial origin. This neoplasm is highly malignant and diagnosis is often delayed due to the vague presentation of clinical symptoms. A case report and concise review of the current diagnostic criteria and surgical treatment are provided to aid in the detection and treatment of this malignancy. We present a case of a 56-year-old female who presented with massive splenomegaly secondary to angiosarcoma of the spleen. The patient suffered from longstanding symptomatic anemia and thrombocytopenia. Diagnosis of a splenic angiosarcoma can be difficult due to the vague presentation and lack of concrete risk factors. Early identification and splenectomy are paramount. However, it is an aggressive malignancy with poor prognosis. We reviewed the literature of the current diagnostic and surgical treatment of primary splenic angiosarcoma.

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Anders Kindberg Boysen ◽  
Paw Jensen ◽  
Preben Johansen ◽  
Karen Dybkær ◽  
Mette Nyegaard

Aggressive NK-cell leukemia is a rare malignancy with neoplastic proliferation of natural killer cells. It often presents with constitutional symptoms, a rapid declining clinical course, and a poor prognosis with a median survival of a few months. The disease is usually resistant to cytotoxic agents, and no treatment has emerged as the standard of care for these patients. We report a case of an 18-year-old male who obtains complete remission following two lines of combination chemotherapy. We describe in details our regimens for induction chemotherapy and perform a review of existing literature concerning treatment of aggressive NK-cell leukemia.


Author(s):  
Marcelo L. P. Sobral ◽  
Luis A. S. Santos ◽  
Gilmar G. Santos ◽  
Noedir A. G. Stolf

The Foot ◽  
2021 ◽  
pp. 101796
Author(s):  
Elias S. Vasiliadis ◽  
Christos Vlachos ◽  
Angelos Antoniades ◽  
Eftychios Papagrigorakis ◽  
Matthaios Bakalakos ◽  
...  

Author(s):  
Núria Carreras ◽  
Cristian de Guirior ◽  
Meritxell Munmany ◽  
Mariona Rius ◽  
Roser Nonell ◽  
...  

2003 ◽  
Vol 127 (9) ◽  
pp. e371-e373 ◽  
Author(s):  
Hong Qi Peng ◽  
Albert E. Stanek ◽  
Saul Teichberg ◽  
Barry Shepard ◽  
Ellen Kahn

Abstract Malignant rhabdoid tumor of the kidney is an uncommon renal tumor in children. The tumor has aggressive behavior and a poor prognosis and is extremely rare in adults; only 3 cases of renal rhabdoid tumors have been reported in adults. We describe here the microscopic, immunohistochemical, and electron microscopic characteristics of another case in a 38-year-old woman. This case reinforces the importance of recognizing this entity in the adult population.


2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Diana Olsen ◽  
Charlene Molloy ◽  
P. S. Sriram

Angiosarcoma is a rare but highly malignant tumor arising from vascular endothelial cells. Angiosarcoma commonly arises from the heart, liver, breast, and skin including the scalp. Angiosarcoma metastasizing to the lungs can present as either pneumothorax, hemothorax, or pleural effusions. They can rarely present as rapidly enlarging thin-walled pulmonary cysts. A review of the literature is included.


Neurosurgery ◽  
1991 ◽  
Vol 29 (4) ◽  
pp. 599-602 ◽  
Author(s):  
B. Aesch ◽  
E. Lioret ◽  
B. de Toffol ◽  
M. Jan

Abstract A 25-year-old man was hospitalized after suffering a subarachnoid hemorrhage. Arteriograms disclosed two arteriovenous malformations, one of which was asymptomatic. Rendu-Osler-Weber disease was suspected because of the concomitant existence of cutaneous telangiectases, Review of the literature shows that in 12 previously published cases involving multiple arteriovenous malformations, this diagnosis was established five times. The indications for surgical treatment are discussed.


Author(s):  
Jose F. Dominguez ◽  
Smit Shah ◽  
Eric Feldstein ◽  
Christina Ng ◽  
Boyi Li ◽  
...  

AbstractSinus pericranii (SP) are abnormal vascular connections between extracranial scalp venous channels and intracranial dural sinuses. This vascular abnormality rarely results in significant sequelae, but in select cases, it can be symptomatic. We describe the case of a 7-year-old girl with an SP who experienced intermittent visual, motor, and sensory symptoms not previously described in the literature. Her symptoms resolved after surgical treatment of the SP. We propose a mechanism for her symptoms and the rationale for the role of neurosurgical intervention along with a review of the literature.


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